1RTL: CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR

PDB ID: 1RTLDownload
MMDB ID: 30831
PDB Deposition Date: 2003/12/10
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Hepacivirus hominis▼
Similar Structures:
Biological Unit for 1RTL: tetrameric; determined by author and by software (PISA)
Molecular Components in 1RTL
Label Count Molecule
Proteins (4 molecules)
2
NS3 Protease/helicase
Molecule annotation
2
Ns4a Cofactor
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC IONZINC ION
2
1
N-[(2R,3S)-1-((2S)-2-{[(CYCLOPENTYLAMINO)CARBONYL]AMINO}-3-METHYLBUTANOYL)-2-(1-FORMYL-1-CYCLOBUTYL)PYRROLIDINYL]CYCLOPROPANECARBOXAMIDEN-[(2R,3S)-1-((2S)-2-{[(CYCLOPENTYLAMINO)CARBONYL]AMINO}-3-METHYLBUTANOYL)-2-(1-FORMYL-1-CYCLOBUTYL)PYRROLIDINYL]CYCLOPROPANECARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303