1RIW: Thrombin in complex with natural product inhibitor Oscillarin

PDB ID: 1RIWDownload
MMDB ID: 30270
PDB Deposition Date: 2003/11/18
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.04  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 1RIW: tetrameric; determined by author and by software (PISA)
Molecular Components in 1RIW
Label Count Molecule
Proteins (4 molecules)
1
Thrombin Light Chain
Molecule annotation
1
Thrombin Heavy Chain, B
Molecule annotation
1
Thrombin Heavy Chain, C
Molecule annotation
1
Hirudin IIB
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
SODIUM IONSODIUM ION
3
1
(2R,3AS,6R,7AS)-N-(2-{1-[AMINO(IMINO)METHYL]-2,5-DIHYDRO-1H-PYRROL-3-YL}ETHYL)-6-HYDROXY-1-{N-[(2S)-2-HYDROXY-3-PHENYLPROPANOYL]PHENYLALANYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE(2R,3AS,6R,7AS)-N-(2-{1-[AMINO(IMINO)METHYL]-2,5-DIHYDRO-1H-PYRROL-3-YL}ETHYL)-6-HYDROXY-1-{N-[(2S)-2-HYDROXY-3-PHENYLPROPANOYL]PHENYLALANYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303