1PY2: Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2

PDB ID: 1PY2Download
MMDB ID: 26101
PDB Deposition Date: 2003/7/7
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 1PY2: monomeric; determined by author and by software (PQS)
Molecular Components in 1PY2
Label Count Molecule
Protein (1 molecule)
1
Interleukin-2
(Gene symbol: IL2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-PENTANOYLAMINO)-ACETYL]-PIPERIDIN-4-YL}-1-METHYL-1H-PYRAZOL-3-YL)-PHENOXYMETHYL]-FURAN-2-CARBOXYLIC ACID5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-PENTANOYLAMINO)-ACETYL]-PIPERIDIN-4-YL}-1-METHYL-1H-PYRAZOL-3-YL)-PHENOXYMETHYL]-FURAN-2-CARBOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303