1P45: Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data

PDB ID: 1P45Download
MMDB ID: 24741
PDB Deposition Date: 2003/4/21
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 1P45: tetrameric; determined by author and by software (PISA,PQS)
Molecular Components in 1P45
Label Count Molecule
Proteins (4 molecules)
4
Enoyl-[acyl-carrier-protein] Reductase [nadh]
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
6
TRICLOSANTRICLOSAN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303