1O7D: The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation

PDB ID: 1O7DDownload
MMDB ID: 22470
PDB Deposition Date: 2002/10/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 1O7D: pentameric; determined by author and by software (PQS)
Molecular Components in 1O7D
Label Count Molecule
Proteins (5 molecules)
1
Lysosomal Alpha-mannosidase
(Gene symbol: MAN2B1)
Molecule annotation
1
Lysosomal Alpha-mannosidase
(Gene symbol: MAN2B1)
Molecule annotation
1
Lysosomal Alpha-mannosidase
(Gene symbol: MAN2B1)
Molecule annotation
1
Lysosomal Alpha-mannosidase
(Gene symbol: MAN2B1)
Molecule annotation
1
Lysosomal Alpha-mannosidase
(Gene symbol: MAN2B1)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
6
alpha-D-mannopyranosealpha-D-mannopyranose
4
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
5
1
ZINC IONZINC ION
6
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303