1O0D: Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor

PDB ID: 1O0DDownload
MMDB ID: 24979
PDB Deposition Date: 2003/2/21
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.44  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1O0D: trimeric; determined by author and by software (PISA)
Molecular Components in 1O0D
Label Count Molecule
Proteins (3 molecules)
1
Thrombin Light Chain
Molecule annotation
1
Thrombin Heavy Chain
Molecule annotation
1
Decapeptide Hirudin Analogue
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2-{2-[(5-CARBAMIMIDOYL-1-METHYL-1H-PYRROL-2-YLMETHYL)-CARBAMOYL]-PYRROL-1-YL}- 1-CYCLOHEXYLMETHYL-2-OXO-ETHYLAMINO)-ACETIC ACID(2-{2-[(5-CARBAMIMIDOYL-1-METHYL-1H-PYRROL-2-YLMETHYL)-CARBAMOYL]-PYRROL-1-YL}- 1-CYCLOHEXYLMETHYL-2-OXO-ETHYLAMINO)-ACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303