1NZ8: Solution Structure of the N-utilization substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus

Citation:
Abstract
NusG is an essential bacterial protein modulator of transcriptional elongation and termination events, and interacts directly with RNA polymerase and Rho protein. Found also in Archaea, NusG shows stretches of sequence similarity to the eukaryotic transcription elongation factor Spt5. Herein, the three-dimensional solution structure of the bacterial NusG from Thermus thermophilus, which shows 43% amino acid sequence similarity to the Escherichia coli NusG, is described, and a survey of NusG and Spt5 amino acid sequences is presented. Although there is a clear evolutionary and functional relationship between these proteins, it is evident from the structural, sequence, and biochemical data that their binding specificities to both nucleic acids and other proteins differ.
PDB ID: 1NZ8Download
MMDB ID: 26769
PDB Deposition Date: 2003/2/17
Updated in MMDB: 2007/11
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Biological Unit for 1NZ8: monomeric; determined by author
Molecular Components in 1NZ8
Label Count Molecule
Protein (1 molecule)
1
Transcription Antitermination Protein Nusg(Gene symbol: TTHA0248)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB
.