1NWL: Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic

PDB ID: 1NWLDownload
MMDB ID: 22448
PDB Deposition Date: 2003/2/6
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 1NWL: monomeric; determined by author
Molecular Components in 1NWL
Label Count Molecule
Protein (1 molecule)
1
Protein-tyrosine Phosphatase, Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
3-(4-{2-[2-(2-BROMO-ACETYLAMINO)-ETHYLDISULFANYL]-ETHYLCARBAMOYL}-CYCLOHEXYLCARBAMOYL)-PYRAZINE-2-CARBOXYLIC ACID3-(4-{2-[2-(2-BROMO-ACETYLAMINO)-ETHYLDISULFANYL]-ETHYLCARBAMOYL}-CYCLOHEXYLCARBAMOYL)-PYRAZINE-2-CARBOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303