1NOW: Human Lysosomal Beta-Hexosaminidase Isoform B In Complex With (2r,3r, 4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium Chloride (Galnac-Isofagomine)

PDB ID: 1NOWDownload
MMDB ID: 22700
PDB Deposition Date: 2003/1/16
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1NOW: dimeric; determined by author and by software (PISA)
Molecular Components in 1NOW
Label Count Molecule
Proteins (2 molecules)
2
Beta-hexosaminidase Beta Chain
(Gene symbol: HEXB)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
2
(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidine(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidine
3
4
GlycerolGlycerin; Propane-1,2,3-triol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303