1NCE: Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717

PDB ID: 1NCEDownload
MMDB ID: 21541
PDB Deposition Date: 2002/12/5
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 1NCE: dimeric; determined by author and by software (PISA)
Molecular Components in 1NCE
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303