1N9A: Farnesyltransferase complex with tetrahydropyridine inhibitors

PDB ID: 1N9ADownload
MMDB ID: 21856
PDB Deposition Date: 2002/11/22
Updated in MMDB: 2004/11
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1N9A: dimeric; determined by author and by software (PISA)
Molecular Components in 1N9A
Label Count Molecule
Proteins (2 molecules)
1
Protein Farnesyltransferase Alpha Subunit
(Gene symbol: Fnta)
Molecule annotation
1
Protein Farnesyltransferase Beta Subunit
(Gene symbol: Fntb)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
3
1
1-{2-[3-(4-CYANO-BENZYL)-3H-IMIDAZOL-4-YL]-ACETYL}-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE1-{2-[3-(4-CYANO-BENZYL)-3H-IMIDAZOL-4-YL]-ACETYL}-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303