1N1L: CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND INHIBITOR (GW472467X)

PDB ID: 1N1LDownload
MMDB ID: 24947
PDB Deposition Date: 2002/10/18
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Orthohepacivirus hominis▼
Similar Structures:
Biological Unit for 1N1L: dimeric; determined by author and by software (PISA)
Molecular Components in 1N1L
Label Count Molecule
Proteins (2 molecules)
1
HCV NS3 Serine Protease
Molecule annotation
1
Ns4a Cofactor
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
{1-[2-(1-FORMYL-PROPYL)-3-METHANESULFONYLAMINO-PYRROLIDINE-1-CARBONYL]-2-METHYL-PROPYL}-CARBAMIC ACID TERT-BUTYL ESTER{1-[2-(1-FORMYL-PROPYL)-3-METHANESULFONYLAMINO-PYRROLIDINE-1-CARBONYL]-2-METHYL-PROPYL}-CARBAMIC ACID TERT-BUTYL ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303