1MF8: Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin

PDB ID: 1MF8Download
MMDB ID: 20981
PDB Deposition Date: 2002/8/9
Updated in MMDB: 2002/11
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 1MF8: tetrameric; determined by author and by software (PISA)
Molecular Components in 1MF8
Label Count Molecule
Proteins (3 molecules)
1
Calmodulin-dependent Calcineurin a Subunit, Alpha Isoform
(Gene symbol: PPP3CA)
Molecule annotation
1
Calcineurin B Subunit Isoform 1
(Gene symbol: PPP3R1)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase a
(Gene symbol: PPIA)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
D
1
CYCLOSPORIN A
1
1
PHOSPHATE IONPHOSPHATE ION
2
4
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303