1M7K: Solution Structure of the SODD BAG Domain

The solution structure of an N-terminally extended construct of the SODD BAG domain was determined by nuclear magnetic resonance spectroscopy. A homology model of the SODD-BAG/HSP70 complex reveals additional possible interactions that are specific for the SODD subfamily of BAG domains while the overall geometry of the complex remains the same. Relaxation rate measurements show that amino acids N358-S375 of SODD which were previously assigned to its BAG domain are not structured in our construct. The SODD BAG domain is thus indeed smaller than the homologous domain in Bag1 defining a new subfamily of BAG domains.
PDB ID: 1M7KDownload
MMDB ID: 20310
PDB Deposition Date: 2002/7/22
Updated in MMDB: 2007/11
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Molecular Components in 1M7K
Label Count Molecule
Protein (1 molecule)
Silencer of Death Domains(Gene symbol: BAG4)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB