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1K4S:
HUMAN DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
PDB ID:
1K4S
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MMDB ID:
73740
PDB Deposition Date:
2001/10/8
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
3.2 Å
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
B, C, D
Homo sapiens
A
Similar Structures:
VAST+
Download sequence data
Molecular Components in 1K4S
Label
Count
Molecule
Protein (1 molecule)
A
1
DNA Topoisomerase I
Nucleotides(3 molecules)
B
1
5'-d(*ap*ap*ap*ap*ap*gp*ap*cp*(5iu)p*(5iu))-3'
C
1
5'-d(*(spt)p*gp*ap*ap*ap*ap*ap*(5iu)p*(5iu)p*(5iu)p*(5iu)p*t)-3'
D
1
5'-d(*ap*ap*ap*ap*ap*tp*(ido)up*(ido)up*(ido)up*(ido)up*cp*ap*ap*ap*gp*(ido)up*cp*(ido)up*(ido)up*(ido)up*(ido)up*t)-3'
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303