1JDQ: Solution Structure of TM006 Protein from Thermotoga maritima

The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMR. Although there was variability among proteomes, overall 20% of these proteins were found to be readily amenable to NMR structure determination. NMR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.
PDB ID: 1JDQDownload
MMDB ID: 18811
PDB Deposition Date: 2001/6/14
Updated in MMDB: 2007/11
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Molecular Components in 1JDQ
Label Count Molecule
Protein (1 molecule)
Hypothetical Protein Tm0983(Gene symbol: TM0983)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB