1IZI: Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants

PDB ID: 1IZIDownload
MMDB ID: 21362
PDB Deposition Date: 2002/10/2
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 1IZI: dimeric; determined by author and by software (PISA)
Molecular Components in 1IZI
Label Count Molecule
Proteins (2 molecules)
2
Proteinase
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
1
{(1S)-1-BENZYL-4-[3-CARBAMOYL-1-(1-CARBAMOYL-2-PHENYL-ETHYLCARBAMOYL)-(S)-PROPYLCARBAMOYL]-2-OXO-5-PHENYL-PENTYL}-CARBAMIC ACID TERT-BUTYL ESTER{(1S)-1-BENZYL-4-[3-CARBAMOYL-1-(1-CARBAMOYL-2-PHENYL-ETHYLCARBAMOYL)-(S)-PROPYLCARBAMOYL]-2-OXO-5-PHENYL-PENTYL}-CARBAMIC ACID TERT-BUTYL ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303