1H7X: Dihydropyrimidine dehydrogenase (DPD) from pig, ternary complex of a mutant enzyme (C671A), NADPH and 5-fluorouracil

PDB ID: 1H7XDownload
MMDB ID: 15635
PDB Deposition Date: 2001/1/19
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.01  Å
Source Organism:
Similar Structures:
Biological Unit for 1H7X: dimeric; determined by author and by software (PQS)
Molecular Components in 1H7X
Label Count Molecule
Proteins (2 molecules)
2
Dihydropyrimidine Dehydrogenase
(Gene symbol: DPYD)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
12
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
2
3
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
4
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
5
2
5-FLUOROURACIL5-FLUOROURACIL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303