1H1B: Crystal structure of human neutrophil elastase complexed with an inhibitor (GW475151)

PDB ID: 1H1BDownload
MMDB ID: 20352
PDB Deposition Date: 2002/7/5
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 1H1B: dimeric; determined by author and by software (PISA)
Molecular Components in 1H1B
Label Count Molecule
Proteins (2 molecules)
2
Leukocyte Elastase
(Gene symbol: ELANE)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
alpha-L-fucopyranosealpha-L-fucopyranose
3
2
(2S)-3-METHYL-2-((2R,3S)-3-[(METHYLSULFONYL)AMINO]-1-{[2-(PYRROLIDIN-1-YLMETHYL)-1,3-OXAZOL-4-YL]CARBONYL}PYRROLIDIN-2-YL)BUTANOIC ACID(2S)-3-METHYL-2-((2R,3S)-3-[(METHYLSULFONYL)AMINO]-1-{[2-(PYRROLIDIN-1-YLMETHYL)-1,3-OXAZOL-4-YL]CARBONYL}PYRROLIDIN-2-YL)BUTANOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303