1GJ7: ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS

PDB ID: 1GJ7Download
MMDB ID: 19157
PDB Deposition Date: 2001/4/27
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 1GJ7: dimeric; determined by author and by software (PISA)
Molecular Components in 1GJ7
Label Count Molecule
Proteins (2 molecules)
1
Urokinase-type Plasminogen Activator
(Gene symbol: PLAU)
Molecule annotation
1
Urokinase-type Plasminogen Activator
(Gene symbol: PLAU)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CITRIC ACIDCITRIC ACID
2
1
6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303