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1FBZ:
Structure-based design of a novel, osteoclast-selective, nonpeptide Src SH2 inhibitor with in vivo anti-resorptive activity
PDB ID:
1FBZ
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MMDB ID:
14099
PDB Deposition Date:
2000/7/17
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
2.4 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 1FBZ: monomeric; determined by author
Molecular Components in 1FBZ
Label
Count
Molecule
Protein (1 molecule)
A
1
Proto-oncogene Tyrosine-protein Kinase LCK
(Gene symbol:
LCK
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
{4-[2-ACETYLAMINO-2-(3-CARBAMOYL-2-CYCLOHEXYLMETHOXY-6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTEN-5YLCARBAMOYL)-ETHYL]-2-PHOSPHONO-PHENYL}-PHOSPHONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303