1DWC: CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS

PDB ID: 1DWCDownload
MMDB ID: 811
PDB Deposition Date: 1992/8/19
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 1DWC: trimeric; determined by author and by software (PISA)
Molecular Components in 1DWC
Label Count Molecule
Proteins (3 molecules)
1
Alpha-thrombin (Small Subunit)
Molecule annotation
1
Alpha-thrombin (Large Subunit)
Molecule annotation
1
Hirudin Iiia
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
amino{[(4S)-5-[(2R,4R)-2-carboxy-4-methylpiperidin-1-yl]-4-({[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}amino)-5-oxopentyl]amino}methaniminiumamino{[(4S)-5-[(2R,4R)-2-carboxy-4-methylpiperidin-1-yl]-4-({[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}amino)-5-oxopentyl]amino}methaniminium
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303