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1DDS:
Molecule: Dihydrofolate Reductase (E.C.1.5.1.3) Complexed With Methotrexate
PDB ID:
1DDS
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MMDB ID:
4188
PDB Deposition Date:
1995/6/29
Updated in MMDB:
1998/11
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Escherichia coli
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1DDS: dimeric; determined by author
Molecular Components in 1DDS
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Dihydrofolate Reductase
(Gene symbol:
folA
)
Chemicals and Non-standard biopolymers (5 molecules)
1
2
Chloride Ion
2
1
Calcium Ion
3
2
Methotrexate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303