1DDS: Molecule: Dihydrofolate Reductase (E.C.1.5.1.3) Complexed With Methotrexate

PDB ID: 1DDSDownload
MMDB ID: 4188
PDB Deposition Date: 1995/6/29
Updated in MMDB: 1998/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1DDS: dimeric; determined by author
Molecular Components in 1DDS
Label Count Molecule
Proteins (2 molecules)
2
Dihydrofolate Reductase
(Gene symbol: folA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
Chloride IonChloride Ion
2
1
Calcium IonCalcium Ion
3
2
MethotrexateMethotrexate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303