1DDR: MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND UREA

PDB ID: 1DDRDownload
MMDB ID: 4189
PDB Deposition Date: 1995/6/29
Updated in MMDB: 1998/11
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 1DDR: dimeric; determined by author and by software (PISA)
Molecular Components in 1DDR
Label Count Molecule
Proteins (2 molecules)
2
Dihydrofolate Reductase
(Gene symbol: folA)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
METHOTREXATEMETHOTREXATE
3
5
UREAUREA
4
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303