1D8E: Zinc-depleted FTase complexed with K-RAS4B peptide substrate and FPP analog

PDB ID: 1D8EDownload
MMDB ID: 12912
PDB Deposition Date: 1999/10/22
Updated in MMDB: 2018/10
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1D8E: trimeric; determined by author and by software (PISA)
Molecular Components in 1D8E
Label Count Molecule
Proteins (3 molecules)
1
Farnesyltransferase (Alpha Subunit)
Molecule annotation
1
Farnesyltransferase (Beta Subunit)
Molecule annotation
1
K-ras4b Peptide Substrate
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ACETATE IONACETATE ION
2
1
[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303