1D6W: STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTROPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1

PDB ID: 1D6WDownload
MMDB ID: 14767
PDB Deposition Date: 1999/10/15
Updated in MMDB: 2000/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 1D6W: dimeric; determined by author
Molecular Components in 1D6W
Label Count Molecule
Proteins (2 molecules)
1
Thrombin
Molecule annotation
1
Decapeptide Inhibitor
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SODIUM IONSODIUM ION
2
1
(5S)-N-[trans-4-(2-amino-1H-imidazol-5-yl)cyclohexyl]-1,3-dioxo-2-[2-(phenylsulfonyl)ethyl]-2,3,5,8-tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazine-5-carboxamide(5S)-N-[trans-4-(2-amino-1H-imidazol-5-yl)cyclohexyl]-1,3-dioxo-2-[2-(phenylsulfonyl)ethyl]-2,3,5,8-tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazine-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303