1C4U: SELECTIVE NON ELECTROPHILIC THROMBIN INHIBITORS WITH CYCLOHEXYL MOIETIES

PDB ID: 1C4UDownload
MMDB ID: 14291
PDB Deposition Date: 1999/9/25
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1C4U: trimeric; determined by author
Molecular Components in 1C4U
Label Count Molecule
Proteins (3 molecules)
1
Thrombin
Molecule annotation
1
Thrombin
Molecule annotation
1
Protein (Hirugen)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
SODIUM IONSODIUM ION
2
1
2-[2-(4-BROMO-BENZENESULFONYL)-ETHYL]-1-3-DIOXO-2,3,5,8-TETRAHYDRO-1H-[1,2,4]TRIAZOLO[1,2-A]PYRIDAZINE-5-CARBOXYLIC ACID(4-CARBAMIMIDOYL-CYCLOHEXYLMETHYL)-AMIDE2-[2-(4-BROMO-BENZENESULFONYL)-ETHYL]-1-3-DIOXO-2,3,5,8-TETRAHYDRO-1H-[1,2,4]TRIAZOLO[1,2-A]PYRIDAZINE-5-CARBOXYLIC ACID(4-CARBAMIMIDOYL-CYCLOHEXYLMETHYL)-AMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303