1AH1: CTLA-4, NMR, 20 STRUCTURES

Citation:
Abstract
The structure of human CTLA-4 reveals that residues Met 99, Tyr 100 and Tyr 104 of the M99YPPPY104 motif are adjacent to a patch of charged surface residues on the A'GFCC' face of the protein. Mutation of these residues, which are conserved in the CTLA-4/CD28 family, significantly reduces binding to CD80 and/or CD86, implicating this patch as a ligand binding site.
PDB ID: 1AH1Download
MMDB ID: 55194
PDB Deposition Date: 1997/4/11
Updated in MMDB: 2011/10
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Biological Unit for 1AH1: monomeric; determined by author
Molecular Components in 1AH1
Label Count Molecule
Protein (1 molecule)
1
Ctla-4(Gene symbol: CTLA4)
Molecule annotation
Chemicals (8 molecules)
1
4
2
1
3
2
4
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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