1A1D: YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY

Citation:
Abstract
RNA polymerase II subunit RPB8 is an essential subunit that is highly conserved throughout eukaryotic evolution and is present in all three types of nuclear RNA polymerases. We report the first high resolution structural insight into eukaryotic RNA polymerase architecture with the solution structure of RPB8 from Saccharomyces cerevisiae. It consists of an eight stranded, antiparallel beta-barrel, four short helical regions and a large, unstructured omega-loop. The strands are connected in classic Greek-key fashion. The overall topology is unusual and contains a striking C2 rotational symmetry. Furthermore, it is most likely a novel associate of the oligonucleotide/oligosaccharide (OB) binding protein class.
PDB ID: 1A1DDownload
MMDB ID: 55017
PDB Deposition Date: 1997/12/10
Updated in MMDB: 2007/10
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Biological Unit for 1A1D: monomeric; determined by author
Molecular Components in 1A1D
Label Count Molecule
Protein (1 molecule)
1
RNA Polymerase(Gene symbol: RPB8)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

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