7LJU: Porcine Dihydropyrimidine Dehydrogenase (DPD) crosslinked with 5-Ethynyluracil (5EU)

PDB ID: 7LJUDownload
MMDB ID: 200755
PDB Deposition Date: 2021/1/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.87  Å
Source Organism:
Similar Structures:
Biological Unit for 7LJU: dimeric; determined by author and by software (PISA)
Molecular Components in 7LJU
Label Count Molecule
Proteins (2 molecules)
2
Dihydropyrimidine Dehydrogenase [nadp(+)]
(Gene symbol: DPYD)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
8
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
2
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
3
2
5-ethynylpyrimidine-2,4(1H,3H)-dione5-ethynylpyrimidine-2,4(1H,3H)-dione
4
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
5
2
1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303