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6QXU:
Human TNKS1 in complex with 6,8-Difluoro-2-[4-(1-hydroxy-1-methyl-ethyl)-phenyl]-3H-quinazolin-4-one
PDB ID:
6QXU
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MMDB ID:
178532
PDB Deposition Date:
2019/3/8
Updated in MMDB:
2019/09
Experimental Method:
x-ray diffraction
Resolution:
1.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6QXU: monomeric; determined by author and by software (PISA)
Molecular Components in 6QXU
Label
Count
Molecule
Protein (1 molecule)
A
1
Poly [adp-ribose] Polymerase Tankyrase-1
(Gene symbol:
TNKS
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
BETA-MERCAPTOETHANOL
2
1
6,8-bis(fluoranyl)-2-[4-(2-oxidanylpropan-2-yl)phenyl]-3~{H}-quinazolin-4-one
3
1
ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303