5WE9: Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 7b (SRI-29731)

PDB ID: 5WE9Download
MMDB ID: 157726
PDB Deposition Date: 2017/7/7
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.804  Å
Source Organism:
Similar Structures:
Biological Unit for 5WE9: monomeric; determined by author
Molecular Components in 5WE9
Label Count Molecule
Protein (1 molecule)
1
Polymerase Acidic Protein
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
2-[(2S)-1-(2,6-difluorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide2-[(2S)-1-(2,6-difluorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303