4EB8: Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with DADMe-ImmG and phosphate

PDB ID: 4EB8Download
MMDB ID: 107298
PDB Deposition Date: 2012/3/23
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4EB8: trimeric; determined by author and by software (PISA)
Molecular Components in 4EB8
Label Count Molecule
Proteins (3 molecules)
3
Purine Nucleoside Phosphorylase
(Gene symbol: PNP)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
PHOSPHATE IONPHOSPHATE ION
2
3
2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303