2XNG: Structure of Aurora-A bound to a selective imidazopyrazine inhibitor

PDB ID: 2XNGDownload
MMDB ID: 84981
PDB Deposition Date: 2010/8/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.605  Å
Source Organism:
Similar Structures:
Biological Unit for 2XNG: monomeric; determined by author and by software (PISA)
Molecular Components in 2XNG
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 6
(Gene symbol: AURKA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamideN-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303