2WD2: a Chimeric Microtubule Disruptor With Efficacy on a Taxane Resistant Cell Line
MMDB ID: 81053help
PDB Deposition Date: 2009/3/19help
Updated in MMDB: 05/2011  help
Experimental Method:
X-Ray Diffraction help
Resolution: 1.49  Åhelp
Source Organism:
Similar Structures: help
Citation: help
Leese MP, Jourdan FL, Kimberley MR, Cozier GE, Thiyagarajan N, Stengel C, Regis-Lydi S, Foster PA, Newman SP, Acharya KR, Ferrandis E, Purohit A, Reed MJ, Potter BVL
Chem.Commun.(Camb.) (2010) 46 p.2907
Biological Unit: monomeric; determined by author, and by software (PISA)help
Molecules and interactionshelp
Label Count Molecule Interactions
Protein and interactions (1 molecule)
1
Carbonic Anhydrase 2
Show annotation
  • Formic Acid
  • MeTHOXYBENZYL)-6-O-SULFAMOYL-7-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE
  • Zinc Ion
Chemicals and interactions (6 molecules)
 -Click for PubChem compound information. 2
  • Carbonic Anhydrase 2
  • MeTHOXYBENZYL)-6-O-SULFAMOYL-7-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE
 -Click for PubChem compound information. 1
  • Carbonic Anhydrase 2
  • Zinc Ion
 -Click for PubChem compound information. 3
  • Carbonic Anhydrase 2
  • Formic Acid
* Click molecule labels to explore molecular sequence information.

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