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Search for Conserved Domains within a protein or coding nucleotide sequence

Enter protein or nucleotide query as accession, gi, or sequence in FASTA format. For multiple protein queries, use Batch CD-Search.


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  • Shennan Lu et al. (2020), "CDD/SPARCLE: the conserved domain database in 2020.", Nucleic Acids Res.48(D1)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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