transducin-like enhancer protein 2 isoform X31 [Mus musculus]
WD40 repeat domain-containing protein( domain architecture ID 1000017)
WD40 repeat domain-containing protein similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
WD40 super family | cl29593 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
70-320 | 8.88e-32 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. The actual alignment was detected with superfamily member cd00200: Pssm-ID: 453027 [Multi-domain] Cd Length: 289 Bit Score: 122.44 E-value: 8.88e-32
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Name | Accession | Description | Interval | E-value | |||||
WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
70-320 | 8.88e-32 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 122.44 E-value: 8.88e-32
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
76-334 | 1.22e-24 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 105.94 E-value: 1.22e-24
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
203-238 | 3.08e-06 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 43.84 E-value: 3.08e-06
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WD40 | pfam00400 | WD domain, G-beta repeat; |
203-238 | 3.20e-05 | |||||
WD domain, G-beta repeat; Pssm-ID: 425662 [Multi-domain] Cd Length: 39 Bit Score: 40.79 E-value: 3.20e-05
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Name | Accession | Description | Interval | E-value | |||||
WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
70-320 | 8.88e-32 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 122.44 E-value: 8.88e-32
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WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
77-321 | 1.13e-29 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 116.67 E-value: 1.13e-29
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
76-334 | 1.22e-24 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 105.94 E-value: 1.22e-24
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
70-319 | 7.32e-24 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 103.63 E-value: 7.32e-24
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
124-334 | 8.76e-17 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 82.06 E-value: 8.76e-17
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
77-254 | 7.05e-16 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 79.36 E-value: 7.05e-16
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WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
202-324 | 2.63e-10 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 60.81 E-value: 2.63e-10
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
174-327 | 1.93e-09 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 59.33 E-value: 1.93e-09
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
203-238 | 3.08e-06 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 43.84 E-value: 3.08e-06
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WD40 | pfam00400 | WD domain, G-beta repeat; |
203-238 | 3.20e-05 | |||||
WD domain, G-beta repeat; Pssm-ID: 425662 [Multi-domain] Cd Length: 39 Bit Score: 40.79 E-value: 3.20e-05
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
157-196 | 4.63e-03 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 34.60 E-value: 4.63e-03
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Blast search parameters | ||||
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