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Conserved domains on  [gi|1039751024|ref|XP_017172455|]
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golgin subfamily B member 1 isoform X4 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1789-2713 3.09e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 3.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1789 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1862
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1863 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1942
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1943 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2022
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2023 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2102
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2103 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2180
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2181 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2260
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2261 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2337
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2338 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2417
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2418 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2497
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2498 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2577
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2578 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2654
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2655 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2713
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-996 1.76e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.76e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  211 QTQAEQAaQKLRVMQRKLEEHEEALLgrAQVVDLLQKELtsaeqrnqvlsqqlqlleAEHNTLKNTMETERQESKTLMEK 290
Cdd:TIGR02168  206 ERQAEKA-ERYKELKAELRELELALL--VLRLEELREEL------------------EELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  291 VELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEKTACILSLQKNEQELQSACAALKE 367
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  368 EN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNEtasqtslpdvnnegdQAVMEETV 437
Cdd:TIGR02168  345 KLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE---------------IERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  438 ASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAGEADGTVCEVSTAGTTLLNRSDSS 508
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  509 peENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE--------------VLDRREVQLMESEG 573
Cdd:TIGR02168  488 --QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaieaalggrlqavVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  574 PPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV-DKSLAVSHVCQCHQGELERLKTq 652
Cdd:TIGR02168  565 LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAlSYLLGGVLVVDDLDNALELAKK- 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  653 vLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLlyqvkeLDV 718
Cdd:TIGR02168  641 -LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELEKALAELRKELEEL------EEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 LAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQS 798
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN 878
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  879 EEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKEL 958
Cdd:TIGR02168  870 ELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1039751024  959 LQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 996
Cdd:TIGR02168  942 QERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 689-1594 5.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 5.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  689 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 768
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  769 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 848
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  849 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 928
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  929 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1008
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1009 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1088
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1089 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1163
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1164 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1243
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1244 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1323
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1324 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1402
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1403 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1478
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1479 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1558
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751024 1559 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1594
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2378-3119 4.54e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2378 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2454
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2455 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2534
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2535 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2614
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2615 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2694
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2695 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2774
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2775 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2847
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2848 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2896
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2897 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 2975
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2976 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3053
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 3054 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3119
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-369 5.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIktqggaalp 126
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEEL--------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    322 -EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  207 TQLSQTQAEQAAQKLRV-MQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESK 285
Cdd:COG1196    401 QLEELEEAEEALLERLErLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  286 TLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQ------KNEQELQ 359
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqnivvEDDEVAA 560

                          330
                   ....*....|
gi 1039751024  360 SACAALKEEN 369
Cdd:COG1196    561 AAIEYLKAAK 570
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1669-1880 4.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1669 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1746
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1747 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1822
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 1823 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1880
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1789-2713 3.09e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 3.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1789 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1862
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1863 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1942
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1943 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2022
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2023 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2102
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2103 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2180
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2181 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2260
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2261 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2337
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2338 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2417
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2418 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2497
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2498 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2577
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2578 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2654
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2655 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2713
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-996 1.76e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.76e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  211 QTQAEQAaQKLRVMQRKLEEHEEALLgrAQVVDLLQKELtsaeqrnqvlsqqlqlleAEHNTLKNTMETERQESKTLMEK 290
Cdd:TIGR02168  206 ERQAEKA-ERYKELKAELRELELALL--VLRLEELREEL------------------EELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  291 VELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEKTACILSLQKNEQELQSACAALKE 367
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  368 EN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNEtasqtslpdvnnegdQAVMEETV 437
Cdd:TIGR02168  345 KLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE---------------IERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  438 ASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAGEADGTVCEVSTAGTTLLNRSDSS 508
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  509 peENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE--------------VLDRREVQLMESEG 573
Cdd:TIGR02168  488 --QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaieaalggrlqavVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  574 PPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV-DKSLAVSHVCQCHQGELERLKTq 652
Cdd:TIGR02168  565 LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAlSYLLGGVLVVDDLDNALELAKK- 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  653 vLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLlyqvkeLDV 718
Cdd:TIGR02168  641 -LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELEKALAELRKELEEL------EEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 LAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQS 798
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN 878
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  879 EEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKEL 958
Cdd:TIGR02168  870 ELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1039751024  959 LQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 996
Cdd:TIGR02168  942 QERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 689-1594 5.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 5.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  689 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 768
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  769 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 848
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  849 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 928
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  929 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1008
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1009 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1088
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1089 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1163
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1164 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1243
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1244 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1323
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1324 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1402
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1403 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1478
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1479 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1558
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751024 1559 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1594
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 717-1359 5.57e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 5.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  717 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 796
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  797 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 876
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  877 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 956
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  957 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1036
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1037 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1116
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1117 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1196
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1197 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1276
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1277 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1356
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1039751024 1357 NYL 1359
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1362-1935 8.43e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 8.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1362 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1437
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1438 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1517
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1518 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1597
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1598 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1675
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1676 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1754
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1755 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1834
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1835 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1912
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1039751024 1913 ------SELEEEKQQLVKEKTKVESEIRK 1935
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 643-1217 1.14e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  643 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 722
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  723 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 802
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  803 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 882
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  883 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 961
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  962 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1041
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1042 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1121
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1122 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1201
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1039751024 1202 PGTGQQEPGPPAPSLE 1217
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2378-3119 4.54e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2378 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2454
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2455 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2534
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2535 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2614
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2615 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2694
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2695 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2774
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2775 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2847
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2848 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2896
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2897 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 2975
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2976 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3053
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 3054 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3119
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1870-2440 1.94e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.54  E-value: 1.94e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1870 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1946
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1947 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2026
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2027 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2101
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2102 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2162
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2163 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2242
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2243 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2315
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2316 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2395
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751024 2396 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2440
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 693-1179 6.07e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.16  E-value: 6.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  693 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 771
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  772 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 839
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  840 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 915
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  916 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 990
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  991 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1068
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1069 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1147
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039751024 1148 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1179
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1782-2553 1.26e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1782 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1861
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1862 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1938
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1939 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2018
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2019 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2098
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2099 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2178
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2179 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2258
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2259 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2338
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2339 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2418
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2419 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2498
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2499 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2553
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 924-1652 2.43e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  924 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1003
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1004 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1080
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1081 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1157
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1158 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1237
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1238 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1317
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1318 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1397
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1398 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1477
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1478 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1557
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1558 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1637
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1039751024 1638 lELEEENDRLRAEAQ 1652
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-369 5.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIktqggaalp 126
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEEL--------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    322 -EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  207 TQLSQTQAEQAAQKLRV-MQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESK 285
Cdd:COG1196    401 QLEELEEAEEALLERLErLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  286 TLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQ------KNEQELQ 359
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqnivvEDDEVAA 560

                          330
                   ....*....|
gi 1039751024  360 SACAALKEEN 369
Cdd:COG1196    561 AAIEYLKAAK 570
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1290-1732 1.37e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1290 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1365
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1366 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1445
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1446 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1522
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1523 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1602
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1603 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1682
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1683 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1732
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
PTZ00121 PTZ00121
MAEBL; Provisional
 673-1188 5.52e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 5.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  673 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 752
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  753 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 829
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  830 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 906
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  907 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 986
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  987 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1066
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1067 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1146
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1039751024 1147 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1188
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2735-3013 1.63e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2735 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2814
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2815 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2894
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2895 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 2974
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039751024 2975 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3013
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2436-3016 4.47e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2436 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2510
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2511 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2577
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2578 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2651
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2652 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2728
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2729 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2808
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2809 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2888
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2889 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 2966
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 2967 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3016
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1669-1880 4.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1669 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1746
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1747 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1822
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 1823 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1880
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2510-2995 2.89e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2510 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2588
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2589 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2668
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2669 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2748
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2749 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2820
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2821 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2892
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2893 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 2961
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1039751024 2962 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 2995
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
PLN02939 PLN02939
transferase, transferring glycosyl groups
 27-255 4.39e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.97  E-value: 4.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   27 ASSDADSSQETAMESNNRIMESTQEDALHRLAEAEKLVVELkdiiSQKDVQLQQKDEALQEEKKAAENKIK--------- 97
Cdd:PLN02939   107 AIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLL----NQARLQALEDLEKILTEKEALQGKINilemrlset 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   98 --KIKLHAKAKI----------MSLNKHMEEIKTQGGAALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSL 165
Cdd:PLN02939   183 daRIKLAAQEKIhveileeqleKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKL 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  166 QAQ---LDQS--EQASQLDKSSAEMEDFVLMKQQ-LQEKEElisTLQTQLSQT--QAEQAA------QKLRVMQRKLEEH 231
Cdd:PLN02939   263 EKErslLDASlrELESKFIVAQEDVSKLSPLQYDcWWEKVE---NLQDLLDRAtnQVEKAAlvldqnQDLRDKVDKLEAS 339

                          250       260
                   ....*....|....*....|....*..
gi 1039751024  232 -EEALLGR--AQVVDLLQKELTSAEQR 255
Cdd:PLN02939   340 lKEANVSKfsSYKVELLQQKLKLLEER 366
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1789-2713 3.09e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 3.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1789 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1862
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1863 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1942
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1943 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2022
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2023 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2102
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2103 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2180
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2181 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2260
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2261 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2337
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2338 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2417
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2418 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2497
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2498 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2577
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2578 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2654
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2655 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2713
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-996 1.76e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.76e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  211 QTQAEQAaQKLRVMQRKLEEHEEALLgrAQVVDLLQKELtsaeqrnqvlsqqlqlleAEHNTLKNTMETERQESKTLMEK 290
Cdd:TIGR02168  206 ERQAEKA-ERYKELKAELRELELALL--VLRLEELREEL------------------EELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  291 VELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEKTACILSLQKNEQELQSACAALKE 367
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  368 EN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNEtasqtslpdvnnegdQAVMEETV 437
Cdd:TIGR02168  345 KLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE---------------IERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  438 ASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAGEADGTVCEVSTAGTTLLNRSDSS 508
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  509 peENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE--------------VLDRREVQLMESEG 573
Cdd:TIGR02168  488 --QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaieaalggrlqavVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  574 PPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV-DKSLAVSHVCQCHQGELERLKTq 652
Cdd:TIGR02168  565 LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAlSYLLGGVLVVDDLDNALELAKK- 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  653 vLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLlyqvkeLDV 718
Cdd:TIGR02168  641 -LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELEKALAELRKELEEL------EEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 LAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQS 798
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN 878
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  879 EEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKEL 958
Cdd:TIGR02168  870 ELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1039751024  959 LQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 996
Cdd:TIGR02168  942 QERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2059-2871 3.23e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 3.23e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2059 IKSQIKQKDEDLL-RRLEQAEEKHR---KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQL 2134
Cdd:TIGR02168  218 LKAELRELELALLvLRLEELREELEelqEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2135 AAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEevrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK 2214
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDE----LAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2215 aqtelqhhqkaydklqeeNKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckEHENNLEGIIKQQEA 2294
Cdd:TIGR02168  374 ------------------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER--LQQEIEELLKKLEEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2295 DIQNCKFSCEQLETDLAasrELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELhQQHSKEIKELENLLSQEEEENVAL 2374
Cdd:TIGR02168  434 ELKELQAELEELEEELE---ELQEEL-ERLEEALEELREELEEAEQALDAAEREL-AQLQARLDSLERLQENLEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2375 EEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD----RIVSDYRQLEERHLSAILEKDQLIQDAAA 2450
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2451 ENNKLKEEMRGLRSHMDDLNSENAKLDAeLVQYRrdLNEVIAIKDsqqkqlLDAQLQQNKELRnectkLEERLKGLEAE- 2529
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRK-ALSYL--LGGVLVVDD------LDNALELAKKLR-----PGYRIVTLDGDl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2530 ---KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGvyHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQ 2606
Cdd:TIGR02168  655 vrpGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL--EKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2607 KEATRKVSEIEdQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQds 2686
Cdd:TIGR02168  733 KDLARLEAEVE-QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR-- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2687 rdhatEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESS 2765
Cdd:TIGR02168  810 -----AELTLLNEEAANLRERLESLeRRIAATERRLEDLEE------QIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2766 HNQVQSISKAMTSLQNERDrlwsELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ 2845
Cdd:TIGR02168  879 LNERASLEEALALLRSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*.
gi 1039751024 2846 MSQEMTELRPlkAQLQESQDQTKALQ 2871
Cdd:TIGR02168  955 EAEALENKIE--DDEEEARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 689-1594 5.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 5.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  689 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 768
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  769 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 848
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  849 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 928
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  929 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1008
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1009 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1088
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1089 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1163
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1164 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1243
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1244 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1323
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1324 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1402
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1403 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1478
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1479 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1558
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751024 1559 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1594
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1290-2123 2.22e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1290 LQDQINEQGLEIQNLKAASVEAQAHTELlKQELESSQLKVAGLEhLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQT 1369
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKAERYKEL-KAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1370 LTTVQTEMVEQERLIKALHTQL----------EMQAKEHEERL-------KQAQVEICELKKKPTELEEETNAKQQLQRK 1432
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELyalaneisrlEQQKQILRERLanlerqlEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1433 LQAALISRKEALKE-----------NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1501
Cdd:TIGR02168  349 LKEELESLEAELEEleaeleelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1502 EMDRflLENQSLSGSCESLKLALggltedkeklmeelesvrsskmaestewqekhKELQKEYEVLLQSYENVSNEAERIQ 1581
Cdd:TIGR02168  429 KLEE--AELKELQAELEELEEEL--------------------------------EELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1582 HVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQkiLELEEENDRLRAEAqpvggTGESM 1661
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL--ISVDEGYEAAIEAA-----LGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1662 EALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVV 1741
Cdd:TIGR02168  548 QAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1742 GKSQErDALSDSAKLEDSEAI------------LMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDREL 1809
Cdd:TIGR02168  628 VDDLD-NALELAKKLRPGYRIvtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1810 SQALENE-------KNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNG 1882
Cdd:TIGR02168  707 LEELEEEleqlrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE----ELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1883 SIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLR 1962
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1963 EKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVT-------KGNLAQAVEHRKKAQAELSSFKILLDDTQ 2035
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2036 SEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQ-------AEEKHRKEKknmqEKLDALHREKAHVEETLAE 2108
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELK----ERYDFLTAQKEDLTEAKET 1018

                          890
                   ....*....|....*
gi 1039751024 2109 IQVSLTRKDQEMKEL 2123
Cdd:TIGR02168 1019 LEEAIEEIDREARER 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1785-2554 8.34e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 8.34e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1785 YLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEE 1864
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1865 EKDDLEerlmNQLAELNGSIgnyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiqga 1944
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL---- 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1945 qkgPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEfvhTESQKDLDVTKGNLAQAVEHRKKA-QAE 2023
Cdd:TIGR02168  368 ---EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2024 LSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKS------QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKL----- 2092
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2093 -----DALHREK---AHVEETLAE-IQVSLTRKDQEMKELQGSLDSTLAQLAAF------------------TKSMSSLQ 2145
Cdd:TIGR02168  522 lgvlsELISVDEgyeAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFlpldsikgteiqgndreiLKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2146 DDRDRVIDEAKKWERRFG---------DAIQTKEEEVRL--KEENCIALKDQL--RQMAIHMEELKITVSRLEHDKEIWE 2212
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKlrPGYRIVTLDGDLvrPGGVITGGSAKTNSSILERRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2213 SKAQTElqhhqkaydKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2292
Cdd:TIGR02168  682 LEEKIE---------ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2293 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEE 2370
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEelKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2371 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIvsdyRQLEERHLSAILEKDQLIQDAAA 2450
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL----EEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2451 ENNKLKEEMRGLRSHMDDLNSENAKLDAEL--------VQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKL--- 2519
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIdnlqerlsEEYSLTLEEAEALENKIEDDEEEAR-RRLKRLENKIKELgpv 987

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751024 2520 -----------EERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNL 2554
Cdd:TIGR02168  988 nlaaieeyeelKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1370-2273 8.81e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.73  E-value: 8.81e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1370 LTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKqaqVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKS 1449
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRREREKAER---YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1450 LQEQLSSARDAVERLTKSLADVESQVS-VQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLT 1528
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1529 EDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLrstESDKRER 1608
Cdd:TIGR02169  336 AEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI---NELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1609 EKqLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS----LKEELEKITLEHKT 1684
Cdd:TIGR02169  409 DR-LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQelydLKEEYDRVEKELSK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1685 LSKEFEALMAEKDALSEETRNLKLQVEaqvlkqasleatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAkledseailm 1764
Cdd:TIGR02169  488 LQRELAEAEAQARASEERVRGGRAVEE------------VLKASIQGVHGTVAQLGSVGERYATAIEVAA---------- 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1765 GDGAKPGVSETfssHDDIKNYLQQLDQLK-GRIAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEVTKRTT 1843
Cdd:TIGR02169  546 GNRLNNVVVED---DAVAKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGVI-------GFAVDLVEFDPKYEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1844 LNQQIQEelcrvTKLKETAEEEKDDLEERLMNQLA----ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEK 1919
Cdd:TIGR02169  616 FKYVFGD-----TLVVEDIEAARRLMGKYRMVTLEgelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKREL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1920 QQLVKEKTKVESEIrKEYMEKIQGAQKgpankshakelqeLLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTES 1999
Cdd:TIGR02169  691 SSLQSELRRIENRL-DELSQELSDASR-------------KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2000 QKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADnlKLKKELQSNkESIKSQIKQKDEDLLRRLEQAEe 2079
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLE- 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2080 khrKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgsldstlAQLAAFTKSMSSLQDDRDRVIDEAKKWE 2159
Cdd:TIGR02169  833 ---KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELE 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2160 RRfgdaIQTKEEEVRLKEENciaLKDQLRQMAIHMEELKITVSRLEHDKEIWES-----KAQTELQHHQKAYDKLQEENK 2234
Cdd:TIGR02169  903 RK----IEELEAQIEKKRKR---LSELKAKLEALEEELSEIEDPKGEDEEIPEEelsleDVQAELQRVEEEIRALEPVNM 975

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 1039751024 2235 ELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2273
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1782-2623 1.04e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.35  E-value: 1.04e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1782 IKNYLQQLDQLKGRIAELEMEKQKDRELSQA----LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK 1857
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1858 LKETAEEEKDDLEERLMNQLaelngsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEy 1937
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1938 mekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2017
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2018 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELqsnkESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNmQEKLDALHR 2097
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQEWKLEQL-AADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2098 EKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRV---IDEAKKWERRFGDAIQTK----- 2169
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2170 -----EEEVRLKEenCIALkdqLRQMAI---------HMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2235
Cdd:TIGR02169  550 nnvvvEDDAVAKE--AIEL---LKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTL 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2236 LTSQLEDARQLYhdSKNELTKLESELKSLKDQTTDLNNSlekckehENNLEGIIKQQEADIQNCKFSCEQLETDLAASRE 2315
Cdd:TIGR02169  625 VVEDIEAARRLM--GKYRMVTLEGELFEKSGAMTGGSRA-------PRGGILFSRSEPAELQRLRERLEGLKRELSSLQS 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2316 LTSRLHDEINAKEQKiISLLSGKEEAIQLAVEELHQQHSK---EIKELENLLSQEEEENVALEEENKRALEKTNQLTEAL 2392
Cdd:TIGR02169  696 ELRRIENRLDELSQE-LSDASRKIGEIEKEIEQLEQEEEKlkeRLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2393 EAIKKESFEQKA-----QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRS 2464
Cdd:TIGR02169  775 HKLEEALNDLEArlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2465 HMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2544
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLGDLKKER--------DELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2545 QGLSKEIKNLQTQLTALQEEG----TLGVYHAQLKAKEEELQRL---NMA----LSSSQKRTADLEEELVCVQKEATRKV 2613
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPeeelSLEDVQAELQRVEEEIRALepvNMLaiqeYEEVLKRLDELKEKRAKLEEERKAIL 1006

                          890
                   ....*....|..
gi 1039751024 2614 SEIE--DQLKKE 2623
Cdd:TIGR02169 1007 ERIEeyEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1440-2341 5.48e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 5.48e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1440 RKEALKenkslqeQLSSARDAVERLTKSLADVESQV-SVQNQEKDAVlgKLTILQEERDKLiaEMDRFLLENQSLSGSCE 1518
Cdd:TIGR02168  174 RKETER-------KLERTRENLDRLEDILNELERQLkSLERQAEKAE--RYKELKAELREL--ELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1519 SLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKL 1598
Cdd:TIGR02168  243 ELQEEL----KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1599 RSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKI 1678
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1679 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALS------D 1752
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEeaeqalD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1753 SAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1832
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1833 LLEEEVTKrttlnqqiQEELCRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnYYQDVTDAQIKNEQLESEMRNLQRCV 1912
Cdd:TIGR02168  559 KKAIAFLK--------QNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-VAKDLVKFDPKLRKALSYLLGGVLVV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1913 SELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHA---------KELQELLREKQQEVKQLQKDCIRYLERIS 1983
Cdd:TIGR02168  629 DDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELEEKIEELEEKIAELEKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1984 ALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQI 2063
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2064 KQKDEDLLRRLEQAeEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS 2143
Cdd:TIGR02168  785 EELEAQIEQLKEEL-KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2144 LQDDRDRVIDEAKKWerrfgdaiqtkEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQHHQ 2223
Cdd:TIGR02168  864 LEELIEELESELEAL-----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2224 KAYDKLQEENKELTSQL--------EDARQLYHDSKNELTKLESELKSLKDQTTDLNN----SLEKCKEHENNLEGIIKQ 2291
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 2292 QEaDIQNCKFSCEQLETDLaaSRELTSRLHD---EINAKEQKIISLLSGKEEA 2341
Cdd:TIGR02168 1009 KE-DLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 717-1359 5.57e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 5.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  717 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 796
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  797 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 876
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  877 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 956
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  957 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1036
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1037 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1116
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1117 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1196
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1197 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1276
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1277 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1356
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1039751024 1357 NYL 1359
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1362-1935 8.43e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 8.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1362 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1437
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1438 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1517
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1518 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1597
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1598 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1675
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1676 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1754
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1755 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1834
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1835 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1912
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1039751024 1913 ------SELEEEKQQLVKEKTKVESEIRK 1935
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 643-1217 1.14e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  643 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 722
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  723 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 802
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  803 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 882
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  883 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 961
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  962 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1041
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1042 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1121
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1122 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1201
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1039751024 1202 PGTGQQEPGPPAPSLE 1217
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1954-2554 2.08e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 2.08e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1954 AKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDD 2033
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR---------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2034 TQSEAARVLADNLKLKKELQSNKESIKSQikqkdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2113
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRREL-----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2114 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRvideakkwerrfgdaIQTKEEEVRLKEENCIALKDQLRQMAIH 2193
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2194 MEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2273
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2274 SLEKCKE-HENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKEEAIQLAVEELH 2350
Cdd:COG1196    506 FLEGVKAaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2351 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES-FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQ 2429
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2430 LEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQN 2509
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751024 2510 KELRNEctkleerlkglEAEKQSLQMSSDALQKEKQGLSKEIKNL 2554
Cdd:COG1196    746 ELLEEE-----------ALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 51-885 2.42e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   51 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAE------NKIKKIKLH-AKAKIMSLNKHMEEIKTQGGA 123
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAErykelkAELRELELAlLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  124 A------LPPEAQA--EELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLD-QSEQASQLDKSSAEMEDFVL-MKQ 193
Cdd:TIGR02168  251 AeeeleeLTAELQEleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQiLRERLANLERQLEELEAQLEeLES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  194 QLQEKEELISTLQTQLSQTQAEQAAQ---------KLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQ 264
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLeaeleeleaELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  265 LLEAEHNTLKNTMETERQE-SKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQrhktEMEE 343
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER----ELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  344 KTACILSLQKNEQELQSACAALKE--ENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSL 421
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  422 PdvNNEGDQAVMEETVAS---LQKRVVELENEKGALLLSSGELEELKAENEKLSSRI--------TLLEAQNRAGEADGT 490
Cdd:TIGR02168  567 Q--NELGRVTFLPLDSIKgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvdDLDNALELAKKLRPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  491 VCEVSTAGTTLLNRSDSSPEENGQavlENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKrpegdyevldRREVQLME 570
Cdd:TIGR02168  645 YRIVTLDGDLVRPGGVITGGSAKT---NSSILERRREIEELEEKIEELEEKIAELEKALAEL----------RKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  571 SEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAgplndagmelsspkldgvdkslavshvcqchQGELERLK 650
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL-------------------------------SKELTELE 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  651 TQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQllyqvkeldvLAELRARVQELE 730
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE----------AANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  731 SSLAEAEKQrgldYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREG 810
Cdd:TIGR02168  831 RRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024  811 TERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQK----DVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLG 885
Cdd:TIGR02168  907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2061-2879 2.43e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 2.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2061 SQIKQKDEDLLRRLEQAEEKHRKEKKNMQEK---LDALHREKAHVEETLAeiqVSLTRKDQEMKELQGSLDSTLAQLAAF 2137
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKrqqLERLRREREKAERYQA---LLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2138 TKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR----LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwes 2213
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE---- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2214 KAQTELQHHQKAYDKLQEENKELTSQLEDARQlyhdsknELTKLESELKSLKDQTTDLNNSLEkckehennlegiikqqe 2293
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERK-------RRDKLTEEYAELKEELEDLRAELE----------------- 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2294 adiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIqlaveELHQQHSKEIKELENLLsqeeeenva 2373
Cdd:TIGR02169  375 -----------EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ-----EELQRLSEELADLNAAI--------- 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2374 leeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENN 2453
Cdd:TIGR02169  430 -----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE----LSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2454 KLKEEMRGLRSHMDDLNSENA---KLDAELVQYRRD------------LNEVIAIKDSQQKQ----LLDAQLQQNKELRN 2514
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaagnrLNNVVVEDDAVAKEaielLKRRKAGRATFLPL 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2515 ECTKLEERLKGLEAEKQSLQMSSDALQKEKQ---------GLSKEIKNLQT--------QLTALQEE----------GTL 2567
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVDLVEFDPKyepafkyvfGDTLVVEDIEAarrlmgkyRMVTLEGElfeksgamtgGSR 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2568 GVYHAQLKAKE--EELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERV 2645
Cdd:TIGR02169  661 APRGGILFSRSepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD-ASRKIGEIEKEIEQLEQEEEKLKERL 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2646 AELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdsrdhatEELGDLKKKYDASlkelaqlkEWQDSSREgdvls 2725
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE-------EALNDLEARLSHS--------RIPEIQAE----- 799

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2726 qaafplstsenvlsrLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEE---GKQR 2802
Cdd:TIGR02169  800 ---------------LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKE 864

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751024 2803 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQEsqdqtkALQVMEEELRQ 2879
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 165-757 2.68e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 2.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  165 LQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQLSQTQA--EQAAQKLRVMQRKLEEHEEALLGRAQVV 242
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAelEELRLELEELELELEEAQAEEYELLAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  243 DLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLsfhnLQEEMHQLQGQLERAGQA 322
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  323 QADLETQYSALQQRHKTEMEEktacILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEIS 402
Cdd:COG1196    374 LAEAEEELEELAEELLEALRA----AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  403 QFVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQN 482
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  483 RAGEADGTVCEVSTAGTTLLNRSDSSPEENGQAVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLD 562
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  563 RREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCH 642
Cdd:COG1196    610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  643 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEarstLAAVTEERDQLLYQVKELDVLAEL 722
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL----LEEEELLEEEALEELPEPPDLEEL 765

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1039751024  723 RARVQELESSLAEAEK--QRGLD-YESQRAQHNLLTEQ 757
Cdd:COG1196    766 ERELERLEREIEALGPvnLLAIEeYEELEERYDFLSEQ 803
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 215-1043 3.26e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 3.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  215 EQAAQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELE 294
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  295 VAERKLSFHNLQEEMHQLQGQLEragQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQ 374
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLE---ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  375 EKHDQAAESAQAMRQLEDQLQQKSKEISQFVNkpnLQKNETASQTSLPDVNNEGDQAVMEetVASLQKRVVELENEKGAL 454
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAE---LKEELEDLRAELEEVDKEFAETRDE--LKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  455 LlssGELEELKAENEKLSSRITLLEAQNRAGEADgtVCEVSTAGTTLLNRSDSSPEENGQAV-----LENTFSQKHKELS 529
Cdd:TIGR02169  405 K---RELDRLQEELQRLSEELADLNAAIAGIEAK--INELEEEKEDKALEIKKQEWKLEQLAadlskYEQELYDLKEEYD 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  530 VLLVEMKEAQEEIAFLKSQLQGKRPEgdyeVLDRREVQLMESEGPPSV--------------------TAGDVLCAPSDE 589
Cdd:TIGR02169  480 RVEKELSKLQRELAEAEAQARASEER----VRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievAAGNRLNNVVVE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  590 SSGPAAEEEQagMKDRHRASEAG--PLN---DAGMELSSPKLDGVDKSL------------AVSHVCQ------------ 640
Cdd:TIGR02169  556 DDAVAKEAIE--LLKRRKAGRATflPLNkmrDERRDLSILSEDGVIGFAvdlvefdpkyepAFKYVFGdtlvvedieaar 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  641 --CHQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEvKESAEEARSTLAAVTEERDQLLYqvkeldv 718
Cdd:TIGR02169  634 rlMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRER-LEGLKRELSSLQSELRRIENRLD------- 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 laELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQS 798
Cdd:TIGR02169  706 --ELSQELSDASRKIGEIEKEI----EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKERevREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF---SMTEKMV 875
Cdd:TIGR02169  780 ALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEqikSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  876 QLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinr 955
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA----QLRELERKIEELEAQIEKKRKRLSELKAKLEA----- 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  956 keLLQKVSQLEEELAKVREDSRKEIPFG--ENERRKLEEDRENRDDPEEWGTSKWREVEASLKQtISEKEVELEGIRRDL 1033
Cdd:TIGR02169  929 --LEEELSEIEDPKGEDEEIPEEELSLEdvQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAI 1005

                          890
                   ....*....|
gi 1039751024 1034 KEKTAAEEEL 1043
Cdd:TIGR02169 1006 LERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1558-2340 3.86e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 3.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1558 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDaeqemeeMKEKMRKFAKSKQQKI 1637
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERL-----RREREKAERYQALLK-------EKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1638 LEleeendrlraeaqpvggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDAL--------SEETRNLKLQ 1709
Cdd:TIGR02169  235 LE-------------------RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEK 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1710 VEAQVLKQASLEAT--EKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILmgdgaKPGVSETFSSHDDIKNYL- 1786
Cdd:TIGR02169  296 IGELEAEIASLERSiaEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR-----RDKLTEEYAELKEELEDLr 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1787 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKrttLNQQIQEELCRVTKLKETAEEEK 1866
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1867 DDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKT--KVESEIRKEYMEKIQG- 1943
Cdd:TIGR02169  448 LEIKK-QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGt 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1944 -AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTESQKDLDVTKGNLAQAVEHR 2017
Cdd:TIGR02169  527 vAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDERRDLSILSEDGVIGFAVDLV 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2018 KKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQIKQKDEDLLRRLEQAEEKH 2081
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2082 RKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2161
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2162 FGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQTELQHHQKAYDKLQEENKEL 2236
Cdd:TIGR02169  767 IEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2237 TSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASREL 2316
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          810       820
                   ....*....|....*....|....
gi 1039751024 2317 TSRLHDEINAKEQKIISLLSGKEE 2340
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEE 949
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1785-2311 3.95e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 3.95e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1785 YLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEE 1864
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1865 EKDDLE---ERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKI 1941
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1942 qgaqkgpankshakELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQ 2021
Cdd:COG1196    390 --------------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2022 AELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLrRLEQAEEKHRKEKKNMQEKLDALHREKAH 2101
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-FLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2102 VEETLAE------IQVSLTRKDQEMKELQGSLDSTLAQLAAF-------------TKSMSSLQDDRDRVIDEAKKWERRF 2162
Cdd:COG1196    535 AYEAALEaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFlpldkiraraalaAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2163 GDAIQTKEEEVRLKEENCIA-------LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2235
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAalrravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 2236 LTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLA 2311
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2018-2583 5.22e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 5.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2018 KKAQAELSSFKI-LLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRrLEQAEEKHRKEKKNMQEKLDALH 2096
Cdd:COG1196    223 KELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-LELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2097 REKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLK 2176
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2177 EENCIALKDQLRQMAIHMEELKITVSRLEhdkeiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTK 2256
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEE--------ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2257 LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLS 2336
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA----------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2337 GKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEA----LEAIKKESFEQKAQLDSFVKS 2412
Cdd:COG1196    524 GAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpLDKIRARAALAAALARGAIGA 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2413 MSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIA 2492
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2493 IKDSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2572
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAE---EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570
                   ....*....|.
gi 1039751024 2573 QLKAKEEELQR 2583
Cdd:COG1196    757 PEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1379-1972 6.89e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 6.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1379 EQERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkptELEEETNAKQQLQRKLQAALISRKEALKEnksLQEQLSSAR 1458
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELE---------ELEAELEELEAELAELEAELEELRLELEE---LELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1459 DAVERLTKSLADVESQVSVQNQEKDAvlgkltiLQEERDKLIAEMDRfllenqslsgsceslklalggLTEDKEKLMEEL 1538
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRE-------LEERLEELEEELAE---------------------LEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1539 EsvrsskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQE 1618
Cdd:COG1196    340 E-----------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1619 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDA 1698
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEAL----EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1699 LSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVvgksqeRDALSDSAKLEDSEAILMGDGAKPGVSETFSS 1778
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV------AVLIGVEAAYEAALEAALAAALQNIVVEDDEV 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1779 HDDIKNYLQQldQLKGRIAELEMEKQKDRELSQALEnEKNALLTQISAKDSELKLLEEevtkRTTLNQQIQEELCRVTKL 1858
Cdd:COG1196    559 AAAAIEYLKA--AKAGRATFLPLDKIRARAALAAAL-ARGAIGAAVDLVASDLREADA----RYYVLGDTLLGRTLVAAR 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1859 KETAEEEKDDLEERLmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1938
Cdd:COG1196    632 LEAALRRAVTLAGRL--REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1039751024 1939 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQ 1972
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1529-2402 9.36e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 9.36e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1529 EDKEKLMEELESVRSSKMAESTEWQEKHKELQKeyevllqsYENVSNEAERIQHVVESVRQ-EKQELYAKLRSTESDKRE 1607
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLER--------LRREREKAERYQALLKEKREyEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1608 REKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEaqpvgGTGESMEallssnssLKEELEKITLEHKTLSK 1687
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-----GEEEQLR--------VKEKIGELEAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1688 EFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAilmgdg 1767
Cdd:TIGR02169  309 SIAEKERELEDAEERLAKLEAEIDKLLAEIEELE--REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF------ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1768 akpgvSETFSSHDDIKnylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQ 1847
Cdd:TIGR02169  381 -----AETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1848 IQEELCRVTKLKETAEEEKDDLEERLmnqlaelngsignyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKT 1927
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEY-------------------------DRVEKELSKLQRELAEAEAQARASEERVR 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1928 --KVESEIRKEYMEKIQG--AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTE 1998
Cdd:TIGR02169  508 ggRAVEEVLKASIQGVHGtvAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDER 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1999 SQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQ 2062
Cdd:TIGR02169  588 RDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGIL 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2063 IKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS 2142
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2143 SLQDDRDRVIDEAKKWERRFGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQT 2217
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2218 ELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2297
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE 906

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2298 NCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEA-----IQLAVEELHQQHSK----------EIKELEN 2362
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledVQAELQRVEEEIRAlepvnmlaiqEYEEVLK 986

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 1039751024 2363 LLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQ 2402
Cdd:TIGR02169  987 RLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2214-3015 2.70e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2214 KAQTELQHHQKAYDKLQEENKELTSQLE------DARQLYHDSKNELTKLESELksLKDQTTDLNNSLEKCKEHENNLEG 2287
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2288 IIKQQEADIQNCKfscEQLETDLAASRELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELHQQHsKEIKELENLLSQE 2367
Cdd:TIGR02168  254 ELEELTAELQELE---EKLEELRLEVSELEEEI-EELQKELYALANEISRLEQQKQILRERLANLE-RQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2368 EEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSA---ILEKDQL 2444
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnneIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2445 IQDAAAENNKLKEEMRGLRSHMDDlnsenakldAELVQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKLEERLK 2524
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEE---------AELKELQAELEELEEELEELQEELERLE-EALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2525 GLEAEKQSLQMSSDALQK---EKQGLSKEIKNLQtqLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS--QKRTADLE 2599
Cdd:TIGR02168  479 AAERELAQLQARLDSLERlqeNLEGFSEGVKALL--KNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqAVVVENLN 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2600 EELVCVQ---KEATRKVS----------EIEDQLKKELKHLHHDAGIMRNETETAE----------------ERVAELAR 2650
Cdd:TIGR02168  557 AAKKAIAflkQNELGRVTflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALE 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2651 DLVEMEQKLLTVTKENKDLMAQ-IQAFGR-----SMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREgdVL 2724
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGgVITGGSaktnsSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--EL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2725 SQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAA 2804
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2805 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTkALQVMEEELRQENLSW 2884
Cdd:TIGR02168  795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2885 QHELRQLRMEKNSWELHERRMKEQFLMA-ISDKDQQLGHLQSLLRELRSS--------SQAQILSTQYQRQASPETSASL 2955
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEeLRELESKRSELRRELEELREKlaqlelrlEGLEVRIDNLQERLSEEYSLTL 953

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 2956 DGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLN----SKFSQLLEEKNVLSTQLSDASQSLR 3015
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKE 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1316-2109 6.68e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 6.68e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1316 ELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEK-EQTLTTVQTEMVE---QERLIKALHTQ 1390
Cdd:TIGR02169  233 EALERQKEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGEleaEIASLERSIAE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1391 LEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEalKENKSLQEqlssardaverltksLAD 1470
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE--ELEDLRAE---------------LEE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1471 VESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRsskmAEST 1550
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA----LEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1551 EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFA 1630
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1631 KSKQQKILELE-EENDRLRAEAQPVGGTGESMEALLSSNSSLKEE---LEKITLEHKTLSKefealMAEKDALS------ 1700
Cdd:TIGR02169  532 SVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflpLNKMRDERRDLSI-----LSEDGVIGfavdlv 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1701 ---EETRNLKLQVEAQVLKQASLEATEKSDE-------PKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgdgakP 1770
Cdd:TIGR02169  607 efdPKYEPAFKYVFGDTLVVEDIEAARRLMGkyrmvtlEGELFEKSGAMTGGSRAPRGGILFSRSEPAEL---------Q 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1771 GVSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQ 1849
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSeLRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-------SSLE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1850 EELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKV 1929
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEALN-------------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1930 ESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGN 2009
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2010 LAQAVEHRKKAQAELSSFKILLDDTQsEAARVLADNLK----LKKELQSNKESIKS--QIKQKDEDLLRRLEQAE----- 2078
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnml 976

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1039751024 2079 -----EKHRKEKKNMQEKLDALHREKAHVEETLAEI 2109
Cdd:TIGR02169  977 aiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2167-2711 1.49e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2167 QTKEEEVRLKEENCIALKDQLRQMAIhmEELKITVSRLEHDKEiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQL 2246
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2247 YHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINA 2326
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2327 KEQKIISLLSGKEEAIQLAVEELHQQ--HSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKA 2404
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2405 QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENN---------------KLKEEMRGLRSHMDDL 2469
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEaeadyegflegvkaaLLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2470 NSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSK 2549
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2550 EIKNLQTQLTALQEEGTL--------GVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLK 2621
Cdd:COG1196    610 EADARYYVLGDTLLGRTLvaarleaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2622 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKY 2701
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1039751024 2702 DASLKELAQL 2711
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 693-1542 1.58e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.58e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  693 EEARSTLAAVTEERDQLLYQVKELD-VLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVK 771
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDlIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  772 IEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE-GTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVE 850
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  851 TLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrteEATKEQVEESGAGSSLKLGHDESGQEGL 930
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELE----REIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  931 QQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE---ELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSK 1007
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1008 WREVE---ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRM---TRDLQSKTKQIDL---------LQEEVTENQ 1072
Cdd:TIGR02169  478 YDRVEkelSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATaievaagnrLNNVVVEDD 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1073 ATIQKLVTgTMDAGNGGSAA--PVKETAASSPPGAggeehwKPELEGrILDLEKDKTQLQKKLQEAL--IARKAILKKAQ 1148
Cdd:TIGR02169  558 AVAKEAIE-LLKRRKAGRATflPLNKMRDERRDLS------ILSEDG-VIGFAVDLVEFDPKYEPAFkyVFGDTLVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1149 EKEKQLKEELReqkdaYHHLQGQFHEQNKEKENIADQLRQLQCQAResidrqlpgtgQQEPGPPAPSLEGISLEDTEPAS 1228
Cdd:TIGR02169  630 EAARRLMGKYR-----MVTLEGELFEKSGAMTGGSRAPRGGILFSR-----------SEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1229 ESDLHAAQPSPPGETAALQ-ATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAA 1307
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1308 SVEAQAHTELLKQELESSQLK--VAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIK 1385
Cdd:TIGR02169  774 LHKLEEALNDLEARLSHSRIPeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1386 ALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAV 1461
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKErdelEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1462 ERLTKSLADVESQVsvqnqEKDAVLGKltiLQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESV 1541
Cdd:TIGR02169  934 SEIEDPKGEDEEIP-----EEELSLED---VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005


                   .
gi 1039751024 1542 R 1542
Cdd:TIGR02169 1006 L 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2378-3119 4.54e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2378 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2454
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2455 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2534
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2535 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2614
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2615 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2694
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2695 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2774
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2775 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2847
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2848 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2896
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2897 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 2975
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2976 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3053
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 3054 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3119
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2356-2894 6.12e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 6.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2356 EIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHL 2435
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2436 SAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKEL 2512
Cdd:COG1196    313 ELEERLEELeeeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2513 RNEcTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQ 2592
Cdd:COG1196    393 RAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA--LEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2593 KRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQ 2672
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2673 IQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKD 2752
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2753 EQLLHLSSELESSHNQVQSISKAMTSLQNERDRLwselekfRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRL 2832
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT-------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 2833 LKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL-----------SWQHELRQLRME 2894
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAleelpeppdleELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 642-1195 8.26e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 8.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  642 HQGELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLA----AVTEERDQLLYQVK 714
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELEsklDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  715 ELDVL----AELRARVQELESSLAEAEKQRG-LDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQ 789
Cdd:TIGR02168  387 KVAQLelqiASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  790 GTQMKTLQSQLEAKEREVREGTER---LRDISQEMEGLSQALSQ----------------------KELEIAK------- 837
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKAllknqsglsgilgvlselisvdEGYEAAIeaalggr 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  838 MDQLLLEKQ----KDVETLQQ------------TIQEKDQQVTELSFSMTEKMVQL-------NEEKFSLGVE------- 887
Cdd:TIGR02168  547 LQAVVVENLnaakKAIAFLKQnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGvakdlvkFDPKLRKALSyllggvl 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  888 -IKTLKEQLNLLSRTEEATK---EQVEESGAGSSLKLGHDE--SGQEGLQQELELLRKESEQRKRKLQAALINRKELLQK 961
Cdd:TIGR02168  627 vVDDLDNALELAKKLRPGYRivtLDGDLVRPGGVITGGSAKtnSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  962 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTAAEE 1041
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEERLEEAEEELAEAEAEIE 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1042 ELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNggSAAPVKETAASSPPGAGGEEHWKPELEGRILD 1121
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER--RIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1122 LEKDKTQLQKKLQEALIARKAI----------LKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQC 1191
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLeealallrseLEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943


                   ....
gi 1039751024 1192 QARE 1195
Cdd:TIGR02168  944 RLSE 947
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 686-1435 9.11e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 9.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  686 EEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSL-------AEAEKQRGL-DYESQRAQHNLLTEQ 757
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEllkekeaLERQKEAIErQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  758 IHSLSIEAKSKDVKIEALQREL----DGVQLQFCEQGTQMKTLQSQLEAK-----------EREVREGTERLRDISQEME 822
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSiaekereledaEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  823 GLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrte 902
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELDRL---- 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  903 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKV---REDSRKE 979
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekeLSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  980 IPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEvelegiRRDLKEKTAAEEELQAVV------------ 1047
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE------RYATAIEVAAGNRLNNVVveddavakeaie 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1048 -------QRMT----RDLQSKTKQIDLLQEE----------------------------VTENQATIQKL---------- 1078
Cdd:TIGR02169  566 llkrrkaGRATflplNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlVVEDIEAARRLmgkyrmvtle 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1079 ---------VTGTMDAGNGGSAAPVKETAASsppgaggeehwkPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE 1149
Cdd:TIGR02169  646 gelfeksgaMTGGSRAPRGGILFSRSEPAEL------------QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1150 KEKQLKEELREQKDAyhhlqGQFHEQNKEK-ENIADQLRQLQcQARESIDRQLPgtgqqepgppapslegiSLEDTEPAS 1228
Cdd:TIGR02169  714 ASRKIGEIEKEIEQL-----EQEEEKLKERlEELEEDLSSLE-QEIENVKSELK-----------------ELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1229 ESDLHAAQPsppgETAALQATVS---VAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDqineqglEIQNLK 1305
Cdd:TIGR02169  771 EEDLHKLEE----ALNDLEARLShsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK-------EIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1306 AASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLI 1384
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 1385 KALHTQLEMQakehEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQA 1435
Cdd:TIGR02169  920 SELKAKLEAL----EEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1126-1988 9.22e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 9.22e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1126 KTQLQKKLQEALIARKAILKKAQEKEKQL---KEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQaresidrqlp 1202
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELallVLRLEELREELEELQEELKEAEEELEELTAELQELEEK---------- 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1203 gtgqqepgppapsLEGISLEDTEpaSESDLHAAQpsppgetAALQATVSvaqiqaqlkemevekeelelKVSSIASELAK 1282
Cdd:TIGR02168  269 -------------LEELRLEVSE--LEEEIEELQ-------KELYALAN--------------------EISRLEQQKQI 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1283 KSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYG 1361
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeAELEELEAELEELESRLEELEEQLETLRS 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1362 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelKKKPTELEEETNAKQQLQRKLQAALISRK 1441
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLE 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1442 EALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQeERDKLIAEMDRFLLENQSLSGSCESL 1520
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLqARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1521 KLALGG-----LTEDKEKLMEELESVRSSKMAEST---EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ 1592
Cdd:TIGR02168  540 EAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1593 ELYAKLRSTESdkrerekqLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLssnsSLK 1672
Cdd:TIGR02168  620 YLLGGVLVVDD--------LDNALEL-----------AKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL----ERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1673 EELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAqvLKQASLEATEKSDEPKDVIEEVTQavvgKSQERDALSD 1752
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ--LRKELEELSRQISALRKDLARLEA----EVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1753 SAKLEDSEAIlmgdgakpgvsetfsshDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1832
Cdd:TIGR02168  751 QLSKELTELE-----------------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1833 LLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCV 1912
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 1913 SELEEEKQQLVKEKTKVESEIRKEYMEkiqgaqkgpankshAKELQELLREKQQEVKQLQKDCIRYLERISALEKT 1988
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRE--------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1955-2564 1.75e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.89  E-value: 1.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1955 KELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT 2034
Cdd:TIGR04523   43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2035 QSEAArvladnlKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVS 2112
Cdd:TIGR04523  123 EVELN-------KLEKQKKENKKNIDKFLTEikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2113 LTR----------KDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEvrlkeencia 2182
Cdd:TIGR04523  196 LLKlelllsnlkkKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI---------- 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2183 lKDQLRQMAIHMEELKITVSRLEhdKEIWESKAQTELQHHQKAydklQEENKELTSQLEdarqlyhDSKNELTKLESELK 2262
Cdd:TIGR04523  266 -KKQLSEKQKELEQNNKKIKELE--KQLNQLKSEISDLNNQKE----QDWNKELKSELK-------NQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2263 SLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAI 2342
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK-IQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2343 QLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR 2422
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2423 IVSDYRQLEERHLSAILEKDQLIQdaaaENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEviaIKDSQQKQLL 2502
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEE----KVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK---DDFELKKENL 559

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2503 DAQLQQNKElrnECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2564
Cdd:TIGR04523  560 EKEIDEKNK---EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1870-2440 1.94e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.54  E-value: 1.94e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1870 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1946
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1947 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2026
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2027 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2101
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2102 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2162
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2163 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2242
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2243 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2315
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2316 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2395
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751024 2396 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2440
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 289-1078 2.54e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 2.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  289 EKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQqrhkTEMEEKTACILSLQKNEQELQSACAALKEE 368
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  369 NSKLLQEKhdqaAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASqtslpdvnnegdqavMEETVASLQKRVVELE 448
Cdd:TIGR02168  297 ISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------LEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  449 NEkgalllssgeLEELKAENEKLSSRITLLEAQNRAgeadgtvcevstagttllNRSDSSPEENGQAVLENTFSQKHKEL 528
Cdd:TIGR02168  358 AE----------LEELEAELEELESRLEELEEQLET------------------LRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  529 SVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRA 608
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE--ELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  609 SEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCHQGELerlkTQVLELETSLHTAEETY---------KRNLSEKVKEIS 679
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL----SELISVDEGYEAAIEAAlggrlqavvVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  680 SLTQ---------------------LSEEVKESAEEARSTLAAVTEERDQL----------LYQVKELDVLAELRARVQE 728
Cdd:TIGR02168  564 FLKQnelgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  729 LES---------------SLAEAEKQRGLDYESQ-----RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCE 788
Cdd:TIGR02168  644 GYRivtldgdlvrpggviTGGSAKTNSSILERRReieelEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  789 QGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF 868
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  869 SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE------EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE 942
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATErrledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  943 QRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEK 1022
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751024 1023 EVELEGIRRDLKEKT-----------AAEEELQAVVQRmtrdLQSKTKQIDLLQEEVTENQATIQKL 1078
Cdd:TIGR02168  964 EDDEEEARRRLKRLEnkikelgpvnlAAIEEYEELKER----YDFLTAQKEDLTEAKETLEEAIEEI 1026
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2050-2627 4.64e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.35  E-value: 4.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2050 KELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLdalhrekahveETLAEIQVSLTRKDQEMKELQGSLDS 2129
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKI-----------KILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2130 TLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKE 2209
Cdd:TIGR04523  104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2210 IWESK-AQTELQHHQKAY-----DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2283
Cdd:TIGR04523  184 NIQKNiDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2284 NLEGIIKQQEADIQNCKFSCEQLETDLaasRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENL 2363
Cdd:TIGR04523  264 KIKKQLSEKQKELEQNNKKIKELEKQL---NQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2364 LSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2440
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2441 KDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDA---ELVQYRRDLNEVIAIKDS---QQKQLLDAQLQQNKE 2511
Cdd:TIGR04523  421 KELLekeIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNtreSLETQLKVLSRSINKIKQnleQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2512 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS 2591
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSL 580

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1039751024 2592 QKRTADLEEELVCVQKEATRKVSEIE------DQLKKELKHL 2627
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEekekkiSSLEKELEKA 622
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2234-2839 4.97e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 4.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2234 KELTSQLEDARQlYHDSKNELTKLESELKSLKDQttdlnnslekckehenNLEGIIKQQEADIQNCKFSCEQLETDLAAS 2313
Cdd:COG1196    203 EPLERQAEKAER-YRELKEELKELEAELLLLKLR----------------ELEAELEELEAELEELEAELEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2314 RELTSRLHDEINAKEQKIiSLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALE 2393
Cdd:COG1196    266 EAELEELRLELEELELEL-EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2394 AIKkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEemrgLRSHMDDLNSEN 2473
Cdd:COG1196    345 ELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE----LEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2474 AKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEikN 2553
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL--L 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2554 LQTQLTALQEEGTLGVYHAQLKAKEEEL-QRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHlhHDAG 2632
Cdd:COG1196    495 LLLEAEADYEGFLEGVKAALLLAGLRGLaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2633 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2712
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2713 EWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEK 2792
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751024 2793 FRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL 2839
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 693-1179 6.07e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.16  E-value: 6.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  693 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 771
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  772 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 839
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  840 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 915
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  916 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 990
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  991 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1068
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1069 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1147
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039751024 1148 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1179
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1117-1884 6.97e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 6.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1117 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKE---ELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1193
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1194 RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASEsdlhaaqpsppgetaalQATVSVAQIQAQLKEMEVEKEELELKV 1273
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------------ELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1274 SSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELEsSQLKVAGLEHLKTLQPELDALHKHMGQKE 1353
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE-ELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1354 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMqAKEHEERLKQAQVEICELKKKPTELEEETNAKQQ----- 1428
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSElisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1429 ----------LQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTkSLADVESQVSVQN--QEKDAVLGKLTILQEER 1496
Cdd:TIGR02168  533 egyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD-SIKGTEIQGNDREilKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1497 DKLIAEMDRFLlenqSLSGSCESLKLALGGLTEDKEKLM-------------------EELESVRSSKMAESTEWQEKHK 1557
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1558 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1637
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1638 LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEAL-----MAEKDALSEETRNLKLQVEA 1712
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLrerleSLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1713 QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvsetfSSHDDIKNYLQQLDQL 1792
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR-------ELESKRSELRRELEEL 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1793 KGRIAELEMEKQKdrelsqaLENEKNALLTQISAKDS-ELKLLEEEVTKRTTLNQQIQEELCRVT-KLKE------TAEE 1864
Cdd:TIGR02168  921 REKLAQLELRLEG-------LEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLEnKIKElgpvnlAAIE 993

                          810       820
                   ....*....|....*....|...
gi 1039751024 1865 EKDDLEER---LMNQLAELNGSI 1884
Cdd:TIGR02168  994 EYEELKERydfLTAQKEDLTEAK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1554-2150 6.97e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1554 EKHKELQKEYEVLlqsyenvsnEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSK 1633
Cdd:COG1196    213 ERYRELKEELKEL---------EAELLLLKLRELEAELEEL-----EAELEELEAELEELEAELAELEAELEELR--LEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1634 QQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQ 1713
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1714 VLKQASLEATEKSDEpKDVIEEVTQAVVGKSQERDALSDSAKLEdseailmgdgakpgvsetfsshDDIKNYLQQLDQLK 1793
Cdd:COG1196    357 EAELAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELA----------------------AQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1794 GRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERL 1873
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1874 mNQLAELNGSIGNYYQDVTDAQIKNEQ--LESEMRNLQRCVSELEEE---------KQQLVKEKTKVESEIRKEYMEKIQ 1942
Cdd:COG1196    494 -LLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLIGVEAAYEAAleaalaaalQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1943 GAQKGPANKSHAKELQELLREKQQEVKQLqkDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2022
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAV--DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2023 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2102
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751024 2103 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDR 2150
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 889-1594 1.05e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  889 KTLKEQLNLLSRTEEATK-EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE 967
Cdd:COG1196    216 RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  968 ELAKVREDSRKEipfgeNERRKLEEDRENRDDPEEwgtSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1047
Cdd:COG1196    296 ELARLEQDIARL-----EERRRELEERLEELEEEL---AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1048 QRMTRDLQSKTKQIDLLQEEVTENQATIQklvtgtmdagnggsaapvketaassppgaggeehwkpELEGRILDLEKDKT 1127
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAA-------------------------------------ELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1128 QLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPgtgqq 1207
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE----- 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1208 epgppapslegislEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAkkseev 1287
Cdd:COG1196    486 --------------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA------ 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1288 lllqdqineqGLEIQNLKAASVEAQAHTELLKQELESsqlKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKE 1367
Cdd:COG1196    546 ----------AALQNIVVEDDEVAAAAIEYLKAAKAG---RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1368 QTLTTVQTEMVEQERLIKALHT-QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEAlKE 1446
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA-EE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1447 NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1526
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 1527 LTEDkeklMEELESVRSskMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1594
Cdd:COG1196    772 LERE----IEALGPVNL--LAI-----EEYEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1276-1800 5.57e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 5.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1276 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvAGLEHLKTLQPELDALHKHMGQKEEE 1355
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE---QDIARLEERRRELEERLEELEEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1356 VNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKkptELEEETNAKQQLQRKLQA 1435
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE---ELLEALRAAAELAAQLEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1436 ALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSG 1515
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1516 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEST--------EWQEKHKELQKEYEVLLQSY------ENVSNEAERIQ 1581
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAALEAALAAAlqnivvEDDEVAAAAIE 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1582 HVVESV--RQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGE 1659
Cdd:COG1196    565 YLKAAKagRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1660 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1739
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 1740 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSEtfsshDDIKNYLQQLDQLKGRIAELE 1800
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEP-----PDLEELERELERLEREIEALG 780
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1782-2553 1.26e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1782 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1861
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1862 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1938
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1939 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2018
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2019 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2098
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2099 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2178
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2179 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2258
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2259 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2338
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2339 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2418
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2419 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2498
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2499 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2553
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 924-1652 2.43e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  924 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1003
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1004 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1080
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1081 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1157
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1158 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1237
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1238 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1317
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1318 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1397
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1398 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1477
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1478 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1557
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1558 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1637
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1039751024 1638 lELEEENDRLRAEAQ 1652
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1897-2628 4.01e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 4.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1897 KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY-MEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDC 1975
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1976 IRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2055
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2056 KESIKSQIKQKDEDLLRRLEQAEEKhrkekknmqEKLDALHREKAHVEETLAEIQvsltRKDQEMKELQGSLDSTLAQLA 2135
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEE---------EELEKLQEKLEQLEEELLAKK----KLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2136 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA 2215
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2216 QTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKdqTTDLNNSLEKCKEHENNLEGIIKQQEAD 2295
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR--LGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2296 IQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISL-------LSGKEEAIQLAVEELHQQHSKEIKELENLLSQEE 2368
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLeidpilnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2369 EENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDdrdrivsdyrQLEERHLSAILEKDQLIQDA 2448
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE----------LAKEEILRRQLEIKKKEQRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2449 AAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLN----EVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLK 2524
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeeeEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2525 GLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVC 2604
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868

                          730       740
                   ....*....|....*....|....
gi 1039751024 2605 VQKEATRKVSEIEDQLKKELKHLH 2628
Cdd:pfam02463  869 LQELLLKEEELEEQKLKDELESKE 892
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-369 5.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIktqggaalp 126
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEEL--------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    322 -EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  207 TQLSQTQAEQAAQKLRV-MQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESK 285
Cdd:COG1196    401 QLEELEEAEEALLERLErLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  286 TLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQ------KNEQELQ 359
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqnivvEDDEVAA 560

                          330
                   ....*....|
gi 1039751024  360 SACAALKEEN 369
Cdd:COG1196    561 AAIEYLKAAK 570
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2418-2697 6.18e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 6.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2418 DDRDRIVSDYrQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdAELVQYRRDLNEViaikDSQ 2497
Cdd:COG4913    593 DDRRRIRSRY-VLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV----ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2498 QKQL--LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQ---EEGTLGVYHA 2572
Cdd:COG4913    667 EREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQdrlEAAEDLARLE 746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2573 QLKAKEEELQRLNMALSSSQKRtADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELAR-- 2650
Cdd:COG4913    747 LRALLEERFAAALGDAVERELR-ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRle 825

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2651 --DLVEMEQKLLT-VTKENKDLMAQIQafgrsmSSLQDSRDHATEELGDL 2697
Cdd:COG4913    826 edGLPEYEERFKElLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
690-955 1.02e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  690 ESAEEARSTLAAVTEE--RDQLLYQVKELD-VLAELRARVQELESSLAEAEKQRgLDYesqRAQHNLLteqihSLSIEAK 766
Cdd:COG3206    145 PDPELAAAVANALAEAylEQNLELRREEARkALEFLEEQLPELRKELEEAEAAL-EEF---RQKNGLV-----DLSEEAK 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  767 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTErlrdiSQEMEGLSQALSQKELEIAKMDQLLLEKQ 846
Cdd:COG3206    216 LLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNH 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  847 KDVETLQQTIQEKDQQVTElsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslklghDESG 926
Cdd:COG3206    291 PDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE--------LEAE 352

                          250       260
                   ....*....|....*....|....*....
gi 1039751024  927 QEGLQQELELLRKESEQRKRKLQAALINR 955
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLAE 381
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1780-2413 1.26e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1780 DDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLK 1859
Cdd:TIGR04523   89 DKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1860 ETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQI------KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEI 1933
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1934 rkeymekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylerisalektvkalefvhtESQKDLDVTKGNLAQA 2013
Cdd:TIGR04523  249 -----------------SNTQTQLNQLKDEQNKIKKQLS-------------------------EKQKELEQNNKKIKEL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2014 VEHRKKAQAELSsfkillddtqseaarvladNLKLKKELQSNKEsIKSQIKQKDEDlLRRLEQAEEKHRKEKKNMQEKLD 2093
Cdd:TIGR04523  287 EKQLNQLKSEIS-------------------DLNNQKEQDWNKE-LKSELKNQEKK-LEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2094 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQddrdRVIDEAKKWERRFGDAIQTKEEEV 2173
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE----SKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2174 RLKEENCIALKDQLRQMAIHMEELKITvsrlEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNE 2253
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQ----DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2254 LTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAasrelTSRLHDEINAKEQKIIS 2333
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK-----KENLEKEIDEKNKEIEE 572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2334 LLSGKE--EAIQLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVK 2411
Cdd:TIGR04523  573 LKQTQKslKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL----EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVK 648


                   ..
gi 1039751024 2412 SM 2413
Cdd:TIGR04523  649 QI 650
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 753-974 1.27e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  753 LLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE 832
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  833 LEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTEL----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE 902
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024  903 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE 974
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1290-1732 1.37e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1290 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1365
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1366 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1445
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1446 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1522
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1523 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1602
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1603 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1682
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1683 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1732
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2149-2995 1.54e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2149 DRVIDE----AKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQK 2224
Cdd:pfam15921   77 ERVLEEyshqVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2225 AYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQttdlnnSLEKCKEHENNLEGIIKQQEADIQNCkfsCE 2304
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEA------SGKKIYEHDSMSTMHFRSLGSAISKI---LR 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2305 QLETDLaasreltSRLHDEINAKEQKIISLLSGKEEAIQLaveeLHQQHSKEIkelENLLSQEEEENVALEEENKRALEK 2384
Cdd:pfam15921  228 ELDTEI-------SYLKGRIFPVEDQLEALKSESQNKIEL----LLQQHQDRI---EQLISEHEVEITGLTEKASSARSQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2385 TNQLTEALEAIKKESFEQKAQldsFVKSMSSLQDDRDRIVSDYRQLEERHLSAIlekDQLIQDAAAENNKLKEEmrglRS 2464
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSM---YMRQLSDLESTVSQLRSELREAKRMYEDKI---EELEKQLVLANSELTEA----RT 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2465 HMDDLNSENAKLDAELVQYRRDLNeviaikdsQQKQLLDAQLQQNKELRNECTkleerlkgleaekqSLQMSSDALQKEK 2544
Cdd:pfam15921  364 ERDQFSQESGNLDDQLQKLLADLH--------KREKELSLEKEQNKRLWDRDT--------------GNSITIDHLRREL 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2545 QGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEelvcvQKEATRKVSEIEDQLKKEL 2624
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSE-----CQGQMERQMAAIQGKNESLEKVSSLTAQLES-----TKEMLRKVVEELTAKKMTL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2625 khlhhdagimrnetETAEERVAELARDLVEMEQKLltvtkenkdlmaqiqafgrsmsslqdsrDHATEELGDLKKKYDAS 2704
Cdd:pfam15921  492 --------------ESSERTVSDLTASLQEKERAI----------------------------EATNAEITKLRSRVDLK 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2705 LKELAQLKEwqdssrEGDVLsqaafplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERD 2784
Cdd:pfam15921  530 LQELQHLKN------EGDHL----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2785 RLWSE-------LEKFRKSEEGKQ-RAAAPSAASSPAEVQSLK---------KAMSSLQNDRDRLLKELKNLQQQYLQMS 2847
Cdd:pfam15921  594 QLEKEindrrleLQEFKILKDKKDaKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2848 QEMTELRplkaqlQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWE---LHERRMKEQFLMAISDKDQQLGHLQ 2924
Cdd:pfam15921  674 EDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAKRGQIDALQ 747

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 2925 S----LLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 2995
Cdd:pfam15921  748 SkiqfLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 769-1706 1.86e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  769 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE--AKEREVREGTERLRDISQEMEGLSQALSQKELE--IAKMDQLLLE 844
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLErlRREREKAERYQALLKEKREYEGYELLKEKEALErqKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  845 KQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN----EEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKL 920
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE----RL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  921 GHDESGQEGLQQELELLRKESEQ---RKRKLQAALINRKE----LLQKVSQLEEELAKVRE---DSRKEIPFGENERRKL 990
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEerkRRDKLTEEYAELKEeledLRAELEEVDKEFAETRDelkDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  991 EEDRENRDDPEEWGTSKWREVE---ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEE 1067
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNaaiAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1068 VTENQATIQKLVTGTMDAGNG-GSAAPVKETAASSPPGaggeehwkpeLEGRILDLEKDKTQLQKKLQEALIAR-KAILK 1145
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERvRGGRAVEEVLKASIQG----------VHGTVAQLGSVGERYATAIEVAAGNRlNNVVV 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1146 KAQEKEKQLKEELREQKDAyhhlQGQFHEQNKEKeniadqlrqlqcqaresiDRQLPGTGQQEPGPPAPSLEGISLEDT- 1224
Cdd:TIGR02169  555 EDDAVAKEAIELLKRRKAG----RATFLPLNKMR------------------DERRDLSILSEDGVIGFAVDLVEFDPKy 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1225 EPASesdlhaaqpsppgeTAALQATVSVAQIQAqlkemevekeelelkvssiASELAKKSEEVLLLQDQINEQGLEIQNL 1304
Cdd:TIGR02169  613 EPAF--------------KYVFGDTLVVEDIEA-------------------ARRLMGKYRMVTLEGELFEKSGAMTGGS 659

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1305 KAASVEAQAHTELLKQELESSqlkvaglEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMveqeRLI 1384
Cdd:TIGR02169  660 RAPRGGILFSRSEPAELQRLR-------ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI----EQL 728

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1385 KALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAAL--ISRKEALKENKSLQEQLSSARDAVE 1462
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALndLEARLSHSRIPEIQAELSKLEEEVS 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1463 RLTKSLADVEsqvsvqnqekdavlgkltilqeerdkliAEMDRFLLENQSLsgsceslklalggltedkEKLMEELESVR 1542
Cdd:TIGR02169  809 RIEARLREIE----------------------------QKLNRLTLEKEYL------------------EKEIQELQEQR 842

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1543 SskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEM 1622
Cdd:TIGR02169  843 I-------DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1623 KEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGT-------------GESMEALLSSNSSLKEELEKITLEHKTLSKEF 1689
Cdd:TIGR02169  916 RKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledvqaelqrvEEEIRALEPVNMLAIQEYEEVLKRLDELKEKR 995

                          970
                   ....*....|....*..
gi 1039751024 1690 EALMAEKDALSEETRNL 1706
Cdd:TIGR02169  996 AKLEEERKAILERIEEY 1012
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2049-2624 1.97e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 1.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2049 KKELQSNKESIKSQIKQKDEDLLRRLEQAEEKhRKEKKNMQEKLDALHREKAHVEET---LAEIQVSLTRKDQEMKELQG 2125
Cdd:PRK03918   181 LEKFIKRTENIEELIKEKEKELEEVLREINEI-SSELPELREELEKLEKEVKELEELkeeIEELEKELESLEGSKRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2126 SLDSTLAQLAAFTKSMSSLQDDRDRVID---EAKKWERRFGDAIQTKEEEVRLKEENCIaLKDQLRQMAIHMEELKITVS 2202
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKELKElkeKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2203 RLEhdkeiWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKN-ELTKLESELKSLKDQTTDLNNSLEKCKEH 2281
Cdd:PRK03918   339 RLE-----ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGlTPEKLEKELEELEKAKEEIEEEISKITAR 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2282 ENNLEGIIKQQEADIQNCKFS------CEQLETDlAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVE-------- 2347
Cdd:PRK03918   414 IGELKKEIKELKKAIEELKKAkgkcpvCGRELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRElekvlkke 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2348 -ELHQQHS--KEIKELENLLSQEEEENVALEEENKRAL-EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRI 2423
Cdd:PRK03918   493 sELIKLKElaEQLKELEEKLKKYNLEELEKKAEEYEKLkEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEEL 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2424 VSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEeMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLD 2503
Cdd:PRK03918   573 AELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2504 AQLQQNKE----LRNECTKLEERLKGLEAEKQSlqmssdaLQKEKQGLSKEIKNLQTQLTALQEegtlgvyhaqlkaKEE 2579
Cdd:PRK03918   652 LEKKYSEEeyeeLREEYLELSRELAGLRAELEE-------LEKRREEIKKTLEKLKEELEEREK-------------AKK 711

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751024 2580 ELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKEL 2624
Cdd:PRK03918   712 ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEEL 756
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 645-1068 1.98e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  645 ELERLKTQVLELETSLHTAEETYKRNLsekvkeissltqlsEEVKESAEEARSTLAAVTEERDQLLYQVKELD-----VL 719
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKI--------------EELEKQLVLANSELTEARTERDQFSQESGNLDdqlqkLL 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  720 AELRARVQELesSLAEAEKQRGLDYESQRA-QHNLLTEQIHSLSIEAKSKDVKIEALQRELDGvqlqfcEQGTQMKTLQS 798
Cdd:pfam15921  384 ADLHKREKEL--SLEKEQNKRLWDRDTGNSiTIDHLRRELDDRNMEVQRLEALLKAMKSECQG------QMERQMAAIQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKER------EVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVtELSFSMTE 872
Cdd:pfam15921  456 KNESLEKvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV-DLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  873 KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAAL 952
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  953 INR-------KELLQKVSQLEEELAKV-----------------REDSRKEIPFGENERRKLEED-----RENRDDPEEW 1003
Cdd:pfam15921  611 ILKdkkdakiRELEARVSDLELEKVKLvnagserlravkdikqeRDQLLNEVKTSRNELNSLSEDyevlkRNFRNKSEEM 690

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 1004 GTSKWReveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1068
Cdd:pfam15921  691 ETTTNK-----LKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI 750
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2071-2669 2.31e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 2.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2071 LRRLEQAEEKHRKEKKNMQEKLDALHRE---KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDD 2147
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2148 RDRVIDEAKKWERRFGDAiqtKEEEVRLKEenciaLKDQLRQMAIHMEELKITVSRLEhdkeiweskaqtELQHHQKAYD 2227
Cdd:PRK03918   237 KEEIEELEKELESLEGSK---RKLEEKIRE-----LEERIEELKKEIEELEEKVKELK------------ELKEKAEEYI 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2228 KLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdIQNCKFSCEQLE 2307
Cdd:PRK03918   297 KLSEFYEEYLDELREI-------EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2308 TDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQqhskEIKELENLLSQEEEENVALEEENKRALEKTNQ 2387
Cdd:PRK03918   369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKKAKGKCPVCGRE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2388 LTEAleaikkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSaiLEKDQLIQDAAAENNKLKEEMRGLRSHMD 2467
Cdd:PRK03918   445 LTEE---------HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLK 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2468 DLNSENAKLDAElvQYRRDLNEVIAIKdSQQKQLLDaQLQQNKELRNECTKLEERLKGLEAEKQSLQ--------MSSDA 2539
Cdd:PRK03918   514 KYNLEELEKKAE--EYEKLKEKLIKLK-GEIKSLKK-ELEKLEELKKKLAELEKKLDELEEELAELLkeleelgfESVEE 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2540 LQKEKQGLSK------EIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKV 2613
Cdd:PRK03918   590 LEERLKELEPfyneylELKDAEKELEREEKE--LKKLEEELDKAFEELAETEKRLEELRKE---LEELEKKYSEEEYEEL 664

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 2614 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDL 2669
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKAL 720
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1365-2169 2.49e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.69  E-value: 2.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1365 EKEQTLTTVQTEMVE--QERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKE 1442
Cdd:pfam12128  190 SKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKS 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1443 ALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENqslsgsCESLK 1521
Cdd:pfam12128  270 DETLIASRQEERQETSAELNQLLRTLdDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAD------IETAA 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1522 LALggltedkeklmEELESVRS--SKMAESTEWQE-KHKELQKEYEVLLQsyeNVSNEAERIQHVVESVRQEKQELYAKL 1598
Cdd:pfam12128  344 ADQ-----------EQLPSWQSelENLEERLKALTgKHQDVTAKYNRRRS---KIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1599 RSTESDKRER-EKQLQDaeqemeEMKEKMRKFAKSKQQKILELEEENDRLrAEAQPVGGTGESMEALLSSNSSLKEELEK 1677
Cdd:pfam12128  410 LAVAEDDLQAlESELRE------QLEAGKLEFNEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEA 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1678 ITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEaTEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLE 1757
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELE-LQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLH 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1758 DSEAILMGDGAKPGVSETFSS------HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEknalLTQISAKDSEL 1831
Cdd:pfam12128  562 RTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ----LVQANGELEKA 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1832 KLleEEVTKRTTLnQQIQEELCRVT--------KLKETAEEEKDDLEERLMNQLAELNgSIGNYYQDVTdAQIKNEQLES 1903
Cdd:pfam12128  638 SR--EETFARTAL-KNARLDLRRLFdekqsekdKKNKALAERKDSANERLNSLEAQLK-QLDKKHQAWL-EEQKEQKREA 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1904 EMRNLQRCVSELEEEKQQLVKEKTKVESEirkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQKDCirylERIS 1983
Cdd:pfam12128  713 RTEKQAYWQVVEGALDAQLALLKAAIAAR-----------------RSGAKAELKALETWYKRDLASLGVDP----DVIA 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1984 ALEKTVKalefvhtesqkdldvtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLklkKELQSNKESIKSQI 2063
Cdd:pfam12128  772 KLKREIR------------------TLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQL---SNIERAISELQQQL 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2064 KQKDEDLLRRLeQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVsltrkDQEMKELQGSLDSTLAQLaaftksmSS 2143
Cdd:pfam12128  831 ARLIADTKLRR-AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKE-----DANSEQAQGSIGERLAQL-------ED 897

                          810       820
                   ....*....|....*....|....*.
gi 1039751024 2144 LQDDRDRVIDEAKKWERRFGDAIQTK 2169
Cdd:pfam12128  898 LKLKRDYLSESVKKYVEHFKNVIADH 923
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1795-2557 2.69e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.51  E-value: 2.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1795 RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtklkETAEEEKDDLEERLM 1874
Cdd:TIGR00606  320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-------ELDGFERGPFSERQI 392

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1875 NQLAELNGSiGNYYQDVTDAQIKNEqLESEMRNLQRCVSELEEEKQQL---VKEKTKVESEIRKEYMEKIQGAQKGPANK 1951
Cdd:TIGR00606  393 KNFHTLVIE-RQEDEAKTAAQLCAD-LQSKERLKQEQADEIRDEKKGLgrtIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1952 SHAKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILL 2031
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKN---------SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLT 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2032 DDTQSEAARV-------------LADNLKLKKELQSNKESIKSQIKQKDEDL------LRRLEQAEEKHRKEKKNMQEKL 2092
Cdd:TIGR00606  542 KDKMDKDEQIrkiksrhsdeltsLLGYFPNKKQLEDWLHSKSKEINQTRDRLaklnkeLASLEQNKNHINNELESKEEQL 621

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2093 DALHREKAHVEETLAEiQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKwerrfgdAIQTKEEe 2172
Cdd:TIGR00606  622 SSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR-------VFQTEAE- 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2173 vrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2249
Cdd:TIGR00606  693 ---LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLApgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE 769

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2250 SKNELTKLESELKSLKDQTTDLNnSLEKCKEHENNLEGIIKQQEADIQ-----------NCKFSCEQLETDLAASR-ELT 2317
Cdd:TIGR00606  770 QETLLGTIMPEEESAKVCLTDVT-IMERFQMELKDVERKIAQQAAKLQgsdldrtvqqvNQEKQEKQHELDTVVSKiELN 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2318 SRLHDEINAKEQKIISLLSG-KEEAIQL--------AVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQL 2388
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKSKTNElKSEKLQIgtnlqrrqQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL 928

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2389 TEALEAIKKESFEQ----KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKdqlIQDAAAENNKLKEEMRGLRS 2464
Cdd:TIGR00606  929 ISSKETSNKKAQDKvndiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ---LEECEKHQEKINEDMRLMRQ 1005

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2465 HMDDLNSENAKLDAELVQYRRDlNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2544
Cdd:TIGR00606 1006 DIDTQKIQERWLQDNLTLRKRE-NELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI 1084

                          810
                   ....*....|...
gi 1039751024 2545 QGLSKEIKNLQTQ 2557
Cdd:TIGR00606 1085 KHFKKELREPQFR 1097
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1411-1615 3.18e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1411 ELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT 1490
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1491 ILQEERDKLIAEMDR--------FLLENQSLSGSCESLKLaLGGLTEDKEKLMEELEsvrsskmAESTEWQEKHKELQKE 1562
Cdd:COG4942    101 AQKEELAELLRALYRlgrqpplaLLLSPEDFLDAVRRLQY-LKYLAPARREQAEELR-------ADLAELAALRAELEAE 172

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 1563 YEVLLQSYENVSNEAERIqhvvESVRQEKQELYAKLRSTESDKREREKQLQDA 1615
Cdd:COG4942    173 RAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQE 221
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
676-911 3.42e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  676 KEISSLTQL-------SEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLD----- 743
Cdd:COG4913    204 KPIGDLDDFvreymleEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRaalrl 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  744 YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQmktlqsQLEAKEREVREGTERLRDI 817
Cdd:COG4913    284 WFAQRRLELLeaeleeLRAELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  818 SQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNL 897
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          250
                   ....*....|....
gi 1039751024  898 LSRTEEATKEQVEE 911
Cdd:COG4913    438 IPARLLALRDALAE 451
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2057-2528 3.59e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 3.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2057 ESIKSQIKQKDE-DLLRRLEQaeekHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgSLDSTLAQLA 2135
Cdd:PRK02224   190 DQLKAQIEEKEEkDLHERLNG----LESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-TLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2136 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKIT-----VSRLEHDKEI 2210
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRleecrVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2211 wESKAQTELQHHQKAyDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLK----DQTTDLNNS---LEKCKEHEN 2283
Cdd:PRK02224   345 -ESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgDAPVDLGNAedfLEELREERD 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2284 NLEGIIKQQEADIQNCKFSCEQLETDLAASR-------------------------ELTSRLHD---EINAKEQKIISLL 2335
Cdd:PRK02224   423 ELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedrerveELEAELEDleeEVEEVEERLERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2336 SGKEEAIQL--------AVEELHQQHSKEIKE----LENLLSQEEEENVALEEENKRALEKTNQLTEALEAIkKESFEQK 2403
Cdd:PRK02224   503 DLVEAEDRIerleerreDLEELIAERRETIEEkrerAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV-AELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2404 AQLDSFVKSMSSLQDDRDRIVSDYRQLEERH--LSAILEKDQLIQDAAAEnnkLKEEMRGLRSHMDDLNSENAKLD-AEL 2480
Cdd:PRK02224   582 AELKERIESLERIRTLLAAIADAEDEIERLRekREALAELNDERRERLAE---KRERKRELEAEFDEARIEEAREDkERA 658

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 2481 VQYRRDLNEVIAIKDSQQKQLLDA------QLQQNKELRNECTKLEERLKGLEA 2528
Cdd:PRK02224   659 EEYLEQVEEKLDELREERDDLQAEigavenELEELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1775-1991 3.99e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 3.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1775 TFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQEELCR 1854
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1855 VTKLKETAEEEKDDLEERLMNQLAELNGSIGNYY-------QDVTDAQIK-------NEQLESEMRNLQRCVSELEEEKQ 1920
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllspEDFLDAVRRlqylkylAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 1921 QLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 1991
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1275-1925 3.99e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 3.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1275 SIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKE 1353
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSEIKNDKEQKNKLE 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1354 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELeeeTNAKQQLqRKL 1433
Cdd:TIGR04523  124 VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI---DKIKNKL-LKL 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1434 QAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLEnqsl 1513
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE---- 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1514 sgsCESLKLALGGLTEDKEKLMEELESVRSSKMaestewQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1593
Cdd:TIGR04523  276 ---LEQNNKKIKELEKQLNQLKSEISDLNNQKE------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1594 LYAKLRSTESDKREREKQLqdaeqemeemkekmrkfaKSKQQKILELEEENDRLRaeaqpvggtgESMEALLSSNSSLKE 1673
Cdd:TIGR04523  347 LKKELTNSESENSEKQREL------------------EEKQNEIEKLKKENQSYK----------QEIKNLESQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1674 ELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQvlKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDS 1753
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1754 AKLEDSEailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKL 1833
Cdd:TIGR04523  477 INKIKQN-------LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1834 LEEEVTKrTTLNQQIQEELCRVTKLKETAEEEKDDLEER-------------LMNQLAELNGSIGNYYQDVTDAQIKNEQ 1900
Cdd:TIGR04523  550 DDFELKK-ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKqelidqkekekkdLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          650       660
                   ....*....|....*....|....*
gi 1039751024 1901 LESEMRNLQRCVSELEEEKQQLVKE 1925
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIKET 653
PTZ00121 PTZ00121
MAEBL; Provisional
 673-1188 5.52e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 5.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  673 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 752
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  753 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 829
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  830 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 906
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  907 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 986
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  987 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1066
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1067 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1146
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1039751024 1147 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1188
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2069-2277 7.15e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 7.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2069 DLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDR 2148
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2149 D-------RVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQH 2221
Cdd:COG4942    100 EaqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA----ELEAERAE 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 2222 HQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEK 2277
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
642-1078 9.66e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 9.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  642 HQGELERLKTQVLELETSLHTAEETYK---RNLSEKVKEISSLTQLSEEVKESAEEAR--STLAAVTEERDQLLYQVKEL 716
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIReleERIEELKKEIEELEEKVKELKELKEKAEeyIKLSEFYEEYLDELREIEKR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  717 -----DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLltEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgt 791
Cdd:PRK03918   316 lsrleEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL--EERHELYEEAKAKKEELERLKKRLTGLTPEKLEK-- 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  792 QMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQ------------KELEIAKMDQLLLEKQKDVETLQQTIQEK 859
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEI 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  860 DQQVTELSFSMTEKMVQLNEEK-----FSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQEL 934
Cdd:PRK03918   472 EEKERKLRKELRELEKVLKKESeliklKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  935 ELLRKESEQRKRKLQAALINRKELLQK--------VSQLEEELAKVREDSRKEIPFGENERRKleEDRENRDDPEEWGTS 1006
Cdd:PRK03918   552 EELKKKLAELEKKLDELEEELAELLKEleelgfesVEELEERLKELEPFYNEYLELKDAEKEL--EREEKELKKLEEELD 629

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 1007 KWREVEASLKQTISEKEVELEGIRRDLKEKTaaEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKL 1078
Cdd:PRK03918   630 KAFEELAETEKRLEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1452-1998 9.98e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 9.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1452 EQLSSARDAVERLTK----SLADVESQVSvQNQEKDAVlGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGL 1527
Cdd:PRK02224   169 ERASDARLGVERVLSdqrgSLDQLKAQIE-EKEEKDLH-ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1528 TEDKEKL------MEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRST 1601
Cdd:PRK02224   247 EERREELetleaeIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1602 ESDKREREKQLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlE 1681
Cdd:PRK02224   327 RDRLEECRVAAQAHNEE-----------AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE---E 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1682 HKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEpkDVIEEVTQAV-----------VGKSQERDAL 1750
Cdd:PRK02224   393 IEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR--ERVEEAEALLeagkcpecgqpVEGSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1751 SDS-AKLEDSEAILmgdgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKdRELSQALENEKNALLTQISAKDS 1829
Cdd:PRK02224   471 EEDrERVEELEAEL---------EDLEEEVEEVEERLERAEDLVEAEDRIERLEER-REDLEELIAERRETIEEKRERAE 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1830 EL-----KLLEEEVTKR---TTLNQQIQEELCRVTKLKETAEEEKDDLEErlMNQLAELNGSIGNYYQDVTDAQIKNEQL 1901
Cdd:PRK02224   541 ELreraaELEAEAEEKReaaAEAEEEAEEAREEVAELNSKLAELKERIES--LERIRTLLAAIADAEDEIERLREKREAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1902 esemrnlqrcvSELEEEKQQLVKEKTKVESEIRKEYME-KIQGAQKGPAN-KSHAKELQELLREKQQEVKQLQKDC---- 1975
Cdd:PRK02224   619 -----------AELNDERRERLAEKRERKRELEAEFDEaRIEEAREDKERaEEYLEQVEEKLDELREERDDLQAEIgave 687

                          570       580
                   ....*....|....*....|....*....
gi 1039751024 1976 --IRYLE----RISALEKTVKALEFVHTE 1998
Cdd:PRK02224   688 neLEELEelreRREALENRVEALEALYDE 716
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 47-893 1.12e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQkdeaLQEEKKAAEN----KIKKIKLHAKAKIMSLNKHMEEIKTQgg 122
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLER----LRREREKAERyqalLKEKREYEGYELLKEKEALERQKEAI-- 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  123 aalppEAQAEELSKHNKSSTEEEMEIEKikhELQEKEKLISSLQAQLDQ--SEQASQLDKSSAEME-DFVLMKQQLQEKE 199
Cdd:TIGR02169  243 -----ERQLASLEEELEKLTEEISELEK---RLEEIEQLLEELNKKIKDlgEEEQLRVKEKIGELEaEIASLERSIAEKE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  200 ELISTLQTQLSQTQAEqaaqkLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMET 279
Cdd:TIGR02169  315 RELEDAEERLAKLEAE-----IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  280 ERQE-SKTLMEKVELEVAERKL--SFHNLQEEMHQLQGQLERAGQAQADLEtqysalqqrhktemEEKTACILSLQKNEQ 356
Cdd:TIGR02169  390 YREKlEKLKREINELKRELDRLqeELQRLSEELADLNAAIAGIEAKINELE--------------EEKEDKALEIKKQEW 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  357 ELQSACAALKEENSKLLQEKHDQaaesaqamRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLPDVNNEGDQAVMeET 436
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEY--------DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH-GT 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  437 VASLQKrvVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAGEAdgtvcevstagTTLLNRSDSSPEENGQAV 516
Cdd:TIGR02169  527 VAQLGS--VGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRA-----------TFLPLNKMRDERRDLSIL 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  517 LENTFSqkhkELSVLLVEMKEAQEEIAF-------LKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGDVlcAPSDE 589
Cdd:TIGR02169  594 SEDGVI----GFAVDLVEFDPKYEPAFKyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSG--AMTGGSR--APRGG 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  590 SSGPAAEEEQAgmkdrhraseagplndagmELSSPKLDGVDKSLAVShvcqchQGELERLKTQVLELETSLHTAEetykR 669
Cdd:TIGR02169  666 ILFSRSEPAEL-------------------QRLRERLEGLKRELSSL------QSELRRIENRLDELSQELSDAS----R 716

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  670 NLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELD--------VLAELRARVQELESSLAEAE-KQR 740
Cdd:TIGR02169  717 KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEarieeleeDLHKLEEALNDLEARLSHSRiPEI 796

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  741 GLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQE 820
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751024  821 MEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKFSLGVEIKTLKE 893
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL----KAKLEALEEELSEIEDPKGEDEE 945
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
719-991 1.17e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLS--IEAKSKDVKIEALQRELDGV--QLQFCEQG-TQM 793
Cdd:COG4913    612 LAALEAELAELEEELAEAEERL----EALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELeaELERLDASsDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  794 KTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQtiQEKDQQVTELSFSMTEK 873
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--ALLEERFAAALGDAVER 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  874 MVQLNeekfsLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKES----EQR-KRKL 948
Cdd:COG4913    766 ELREN-----LEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlpeyEERfKELL 840

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1039751024  949 QAALINRKELLQkvSQLEEELAKVRE------DSRKEIPFGENERRKLE 991
Cdd:COG4913    841 NENSIEFVADLL--SKLRRAIREIKEridplnDSLKRIPFGPGRYLRLE 887
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1276-2018 1.17e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1276 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvaglEHLKTLQPELDALHKHMGQKEEE 1355
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAELKEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1356 VNYLYGQLSEKEQTLTTVQTEMveqerliKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLqA 1435
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDEL-------KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI-N 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1436 ALISRKEALKEN--------KSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFL 1507
Cdd:TIGR02169  438 ELEEEKEDKALEikkqewklEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1508 LENQSLSGSCESL-----------KLALGG-----LTEDKEKLMEELESVRSSKMAEST-----EWQEKHKELQKEYEVL 1566
Cdd:TIGR02169  518 ASIQGVHGTVAQLgsvgeryataiEVAAGNrlnnvVVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEDG 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1567 L-----------QSYENVSNEAERIQHVVESVrQEKQELYAKLRSTESDKREREKqlQDAEQEMEEMKEKMRKFAKSKQQ 1635
Cdd:TIGR02169  598 VigfavdlvefdPKYEPAFKYVFGDTLVVEDI-EAARRLMGKYRMVTLEGELFEK--SGAMTGGSRAPRGGILFSRSEPA 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1636 KILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlEHKTLSKEFEALMAEKDALSEETRNLKLQveaqvL 1715
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLEQEEEKLKERLEELEED-----L 746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1716 KQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDsakLEDSEAilmgdgakpgvsetfsshddiknyLQQLDQLKGR 1795
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALND---LEARLS------------------------HSRIPEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1796 IAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEvtkrttlnqqIQEELCRVTKLKETAEEEKDDLEerlmn 1875
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRL-------TLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKEIE----- 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1876 qlaELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAK 1955
Cdd:TIGR02169  858 ---NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024 1956 ELQELLREKQQEV------KQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRK 2018
Cdd:TIGR02169  935 EIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERK 1003
PTZ00121 PTZ00121
MAEBL; Provisional
 1687-2531 1.22e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1687 KEFEALMAEKDALSEETRN-LKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAV-VGKSQERDALSDSAKLEDSEAILM 1764
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEaFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEeARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1765 GDGAKPGVSETFSSHDDiknylqqlDQLKGRIAELEMEKQKDRELSQALENEKnallTQISAKDSELKLLEEevtKRTTL 1844
Cdd:PTZ00121  1157 ARKAEDARKAEEARKAE--------DAKKAEAARKAEEVRKAEELRKAEDARK----AEAARKAEEERKAEE---ARKAE 1221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1845 NQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDvTDAQIKNEQlesemrnlQRCVSELEEekqqlVK 1924
Cdd:PTZ00121  1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR-RQAAIKAEE--------ARKADELKK-----AE 1287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1925 EKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciryleriSALEKTVKAlefvhtesqkdld 2004
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK---------KAEEAKKAA------------- 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2005 vtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHR 2082
Cdd:PTZ00121  1346 ----EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkKKADELKKAAAAKKKAD 1421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2083 KEKKNMQEKLDALHREKAHVEETLAEiqvSLTRKDQEMKELQGSLDSTlaqlaaftksmsslqdDRDRVIDEAKK--WER 2160
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEAKKAD---EAKKKAEEAKKAEEAKKKA----------------EEAKKADEAKKkaEEA 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2161 RFGDAIQTKEEEVRLKEENcialkdqlrqmAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQL 2240
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADE-----------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2241 EDARQLyhDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEadiQNCKFSCEQLEtdlaasreltsrl 2320
Cdd:PTZ00121  1552 KKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE---EEKKMKAEEAK------------- 1613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2321 hdeiNAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQlteALEAIKKESF 2400
Cdd:PTZ00121  1614 ----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK---AEEAKKAEED 1686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2401 EQKAQldsfvksmsslqddrdriVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAEL 2480
Cdd:PTZ00121  1687 EKKAA------------------EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 2481 VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQ 2531
Cdd:PTZ00121  1749 AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2193-2712 1.37e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2193 HMEELKITVSRLEHD----KEIWESK----------AQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2258
Cdd:pfam15921  318 QLSDLESTVSQLRSElreaKRMYEDKieelekqlvlANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2259 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCE-QLETDLAAsreltsrlhdeinakeqkiislLSG 2337
Cdd:pfam15921  398 EQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAA----------------------IQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2338 KEEAIQlAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMS 2414
Cdd:pfam15921  456 KNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEkerAIEATNAEITKLRSRVDLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2415 SLQDDRDRIVSDYRQLEERHLSaILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK 2494
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQ-MAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILK 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2495 DSQQKQLldaqlqqnKELRNECTKLE-ERLKGLEAEKQSLQMSSDaLQKEKQGLSKEIKNLQTQLTALQE---------- 2563
Cdd:pfam15921  614 DKKDAKI--------RELEARVSDLElEKVKLVNAGSERLRAVKD-IKQERDQLLNEVKTSRNELNSLSEdyevlkrnfr 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2564 ------EGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIeDQLKKELKHLHHDAGIMRNE 2637
Cdd:pfam15921  685 nkseemETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI-DALQSKIQFLEEAMTNANKE 763

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 2638 TETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2712
Cdd:pfam15921  764 KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2213-2868 1.62e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2213 SKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2292
Cdd:TIGR04523   29 NKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKI 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2293 EADIQNCKfsceqletdlaasreltsrlhDEINAKEQKIISLLSGKEEaiqlaVEELHQQHSKEIKELENLLsqeeeenv 2372
Cdd:TIGR04523  109 NSEIKNDK---------------------EQKNKLEVELNKLEKQKKE-----NKKNIDKFLTEIKKKEKEL-------- 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2373 aleeenkralektNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAEN 2452
Cdd:TIGR04523  155 -------------EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQI 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2453 NKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQlqqnkelrNECTKLEERLKGLEAEKQS 2532
Cdd:TIGR04523  221 SELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ--------KELEQNNKKIKELEKQLNQ 292

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2533 LQMSSDALQKEKQ-----GLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQK 2607
Cdd:TIGR04523  293 LKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQ---------NQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2608 EATRKVSEIE------DQLKKELKHLHHDAGIMRNETETAEE---------RVAELARDLVEMEQKLLTVT-----KENK 2667
Cdd:TIGR04523  364 ELEEKQNEIEklkkenQSYKQEIKNLESQINDLESKIQNQEKlnqqkdeqiKKLQQEKELLEKEIERLKETiiknnSEIK 443

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2668 DLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQ 2747
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ--KELKSKEKELKKLNEEKKELEEKVKDLTKKISS 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2748 LTSKDEQLLHLSSELESSHNQVQSISKAMTS------LQNERDRLWSELEKFR---KSEEGKQRAAAPSAASSPAEVQSL 2818
Cdd:TIGR04523  522 LKEKIEKLESEKKEKESKISDLEDELNKDDFelkkenLEKEIDEKNKEIEELKqtqKSLKKKQEEKQELIDQKEKEKKDL 601

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2819 KKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTK 2868
Cdd:TIGR04523  602 IKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK 651
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2735-3013 1.63e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2735 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2814
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2815 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2894
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2895 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 2974
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039751024 2975 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3013
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
PTZ00121 PTZ00121
MAEBL; Provisional
 676-1486 1.71e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 1.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  676 KEISSLTQLSEEVKESAEEARSTLAA-VTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRgldyESQRAQHNLL 754
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTETGkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE----DAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  755 TEQIHSLSIEAKSKDV-KIEALQReldGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEmeglSQALSQKEL 833
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAkKAEAARK---AEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA----KKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  834 EIAKMDQllLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESG 913
Cdd:PTZ00121  1233 EEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  914 AGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEED 993
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  994 RENRDDPEEWGTSKWREVEASLKQTISEKEVELegiRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQA 1073
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEA---KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1074 TIQKLVTGTMDAGNGGSAAPVKETAassppgaggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAilKKAQEKEKq 1153
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKA---------EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA--KKAEEAKK- 1535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1154 lKEELREQKDAYHHLQGQFHEQNKEkeniADQLRQLQCQARESIDRQLPGTGQQEpgppapslegisLEDTEPASESDLH 1233
Cdd:PTZ00121  1536 -ADEAKKAEEKKKADELKKAEELKK----AEEKKKAEEAKKAEEDKNMALRKAEE------------AKKAEEARIEEVM 1598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1234 AAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVlllQDQINEQGLEIQNLKAASVEAQA 1313
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIKAAEEAKKAEEDKK 1675

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1314 HTELLKQELESSQLKVaglEHLKTLQPEldalhkhmGQKEEEVnylygQLSEKEQTLTTVQTEMVEQERLIKAlhTQLEM 1393
Cdd:PTZ00121  1676 KAEEAKKAEEDEKKAA---EALKKEAEE--------AKKAEEL-----KKKEAEEKKKAEELKKAEEENKIKA--EEAKK 1737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1394 QAKEHEERLKQAQVEICElKKKPTELEEETNAKQQLQRKLQAALIsrKEALKENKSLQeqlssaRDAVERLTKSLADVES 1473
Cdd:PTZ00121  1738 EAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKR------RMEVDKKIKDIFDNFA 1808

                          810
                   ....*....|...
gi 1039751024 1474 QVSVQNQEKDAVL 1486
Cdd:PTZ00121  1809 NIIEGGKEGNLVI 1821
46 PHA02562
endonuclease subunit; Provisional
 1782-1940 1.85e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.40  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1782 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLnQQIQEELCRVTKLKE- 1860
Cdd:PHA02562   229 AKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIKDk 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1861 --------TAEEEKDDLEERLMNQLA-------ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKE 1925
Cdd:PHA02562   308 lkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDE 387

                          170
                   ....*....|....*
gi 1039751024 1926 KTKVESEIRKEYMEK 1940
Cdd:PHA02562   388 LDKIVKTKSELVKEK 402
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2214-2843 2.07e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2214 KAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLE---GIIK 2290
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEelkEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2291 QQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQ-LAVEELHQQHSKEIKELENLLSQEEE 2369
Cdd:PRK03918   242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2370 ENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRdRIVSDYRQLEERhlsailEKDQLIQDAA 2449
Cdd:PRK03918   322 EINGI----EERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKR------LTGLTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2450 AENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK-----------DSQQKQLLDAQLQQNKELRNECTK 2518
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgreltEEHRKELLEEYTAELKRIEKELKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2519 LEERLKGLEAEKQSLQMssdALQKEKQGLSkeIKNLQTQLTALQEEgtLGVYHAQ-LKAKEEELQRLNMALSSSQKRTAD 2597
Cdd:PRK03918   471 IEEKERKLRKELRELEK---VLKKESELIK--LKELAEQLKELEEK--LKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2598 LEEELVCVQ--KEATRKVSEIEDQLKKELKHLHHdagIMRNETETAEERVAELARDLVEMEQKLLTVtkenKDLMAQIQA 2675
Cdd:PRK03918   544 LKKELEKLEelKKKLAELEKKLDELEEELAELLK---ELEELGFESVEELEERLKELEPFYNEYLEL----KDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2676 FGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRegdvlsqaafplstsenvlsrLEKLNQQLTSKDEQL 2755
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE---------------------YEELREEYLELSREL 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2756 LHLSSELESSHNQVQSISKAMTSLQNERDrlwsELEKFRKseegkqraaapsaasspaEVQSLKKAMSSLQNDRDRlLKE 2835
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEELE----EREKAKK------------------ELEKLEKALERVEELREK-VKK 732


                   ....*...
gi 1039751024 2836 LKNLQQQY 2843
Cdd:PRK03918   733 YKALLKER 740
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2171-2920 2.73e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2171 EEVRLKEENCIALKDQLRQmaiHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2250
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQ---QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2251 KNELTKLESELKSLKDQTTDLNNSLEKCKEHE-NNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQ 2329
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2330 KIISLlSGKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKEsfeqkaqldsf 2409
Cdd:TIGR02169  337 EIEEL-EREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE----------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2410 vksMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRshmddlnsenakldAELVQYRRDLNE 2489
Cdd:TIGR02169  401 ---INELKRELDRLQEELQRLSEE----LADLNAAIAGIEAKINELEEEKEDKA--------------LEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2490 VIAIKDSQQKQLLDAQLQQNKeLRNECTKLEERLKGLEAEKQSL---QMSSDALQKEKQGLSKEIKNLQTQLTALQEEGT 2566
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEEYDR-VEKELSKLQRELAEAEAQARASeerVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2567 LGVYHA---QLKA----------------KEEELQRLN-MALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKH 2626
Cdd:TIGR02169  539 TAIEVAagnRLNNvvveddavakeaiellKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKY 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2627 LHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLTVTKENKD----LMAQIQAFGRSMSSLQDSR 2687
Cdd:TIGR02169  619 VFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAelqrLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2688 DHATEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQAAfplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSH 2766
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL------EELEEDLSSLEQEIENVKSELKELEARIEELE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2767 NQVQSISKAMTSLQNERDRlwselEKFRKSEEgKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQylqm 2846
Cdd:TIGR02169  772 EDLHKLEEALNDLEARLSH-----SRIPEIQA-ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ---- 841

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 2847 sqemteLRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKEQfLMAISDKDQQL 2920
Cdd:TIGR02169  842 ------RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-LRELERKIEEL 908
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1772-2513 2.97e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.12  E-value: 2.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1772 VSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQK----DRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQ 1846
Cdd:pfam15921   94 LNESNELHEKQKFYLRQsVIDLQTKLQEMQMERDAmadiRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIE 173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1847 QIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKN-EQLESEMRNLQRCVSELEEEKQQLVKE 1925
Cdd:pfam15921  174 QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKSE 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1926 ------------KTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciRYLERISALEKTVKALE 1993
Cdd:pfam15921  254 sqnkielllqqhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS---MYMRQLSDLESTVSQLR 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1994 FVHTESQK----DLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKsqiKQKDED 2069
Cdd:pfam15921  331 SELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNK---RLWDRD 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2070 LLRRLEQAEEKHRKEKKNMQekldaLHREKAHVEETLAEIQVSLtrkDQEMKELQGSlDSTLAQLAAFTKSMSSLQDDRD 2149
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNME-----VQRLEALLKAMKSECQGQM---ERQMAAIQGK-NESLEKVSSLTAQLESTKEMLR 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2150 RVIDE--AKKW-----ERRFGD---AIQTKEEEVRLKEENCIALK-----------------DQLRQMAIHMEELKITVS 2202
Cdd:pfam15921  479 KVVEEltAKKMtlessERTVSDltaSLQEKERAIEATNAEITKLRsrvdlklqelqhlknegDHLRNVQTECEALKLQMA 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2203 RLEHDKEIWESKAQTELQ---HHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLnnSLEKCK 2279
Cdd:pfam15921  559 EKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL--ELEKVK 636

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2280 ehennLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiislLSGKEEAIQLAVEELHQQHSKEIKE 2359
Cdd:pfam15921  637 -----LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRN----FRNKSEEMETTTNKLKMQLKSAQSE 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2360 LENLLSQEEEENVALEEENKRALEKTNQLTEaleaikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsail 2439
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQKQITA-----------KRGQIDALQSKIQFLEEAMTNANKEKHFLKE------- 769

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751024 2440 EKDQLIQD---AAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELR 2513
Cdd:pfam15921  770 EKNKLSQElstVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1389-2205 3.19e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 3.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1389 TQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQL-------------- 1454
Cdd:TIGR00606  227 TSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdeqlndl 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1455 -----SSARDAVERLT---KSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1526
Cdd:TIGR00606  307 yhnhqRTVREKERELVdcqRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1527 LTEDKEKLMEELESVRSSKMAES------------TEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1594
Cdd:TIGR00606  387 FSERQIKNFHTLVIERQEDEAKTaaqlcadlqskeRLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1595 YAKLRSTESDKREREKQLQDAEQEME----EMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS 1670
Cdd:TIGR00606  467 EGSSDRILELDQELRKAERELSKAEKnsltETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1671 LKEELEKITLEH--------------KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV---- 1732
Cdd:TIGR00606  547 KDEQIRKIKSRHsdeltsllgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSsyed 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1733 --------------IEEVTQAVVGKSQERDALSDSAKLEDS---EAILMGDGAKPGVSETFSSHDDIKNYLQQLdQLKGR 1795
Cdd:TIGR00606  627 klfdvcgsqdeesdLERLKEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDL-QSKLR 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1796 IAELEMEKQKdrELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDL--EERL 1873
Cdd:TIGR00606  706 LAPDKLKSTE--SELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEES 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1874 MNQLAELNGSIGNYYQDVTDAQIKNEQLESEMR--NLQRCVSELEEEKQQLVKEKTKVESEIR------KEYMEKIQGAQ 1945
Cdd:TIGR00606  784 AKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1946 -KGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAEl 2024
Cdd:TIGR00606  864 sKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK- 942

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2025 ssfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE 2104
Cdd:TIGR00606  943 ------VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQE 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2105 TLAEIQVSLTRKDQEMKELQGSLDSTLAQLA-----AFTKSMSSLQDDRDRV-IDEAKKWERRFGDAIQTKEEEVRLKEE 2178
Cdd:TIGR00606 1015 RWLQDNLTLRKRENELKEVEEELKQHLKEMGqmqvlQMKQEHQKLEENIDLIkRNHVLALGRQKGYEKEIKHFKKELREP 1094

                          890       900
                   ....*....|....*....|....*..
gi 1039751024 2179 NCIALKDQLRQMAIHMEELKITVSRLE 2205
Cdd:TIGR00606 1095 QFRDAEEKYREMMIVMRTTELVNKDLD 1121
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2351-2564 3.60e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 3.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2351 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD--------R 2422
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEaqkeelaeL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2423 IVSDYRQLEERHLSAILEKDQlIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdaelvqyrRDLNEVIAIKDSQQKQLL 2502
Cdd:COG4942    110 LRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2503 DAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2564
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2438-2695 3.95e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2438 ILEKDQLIQDAAAennkLKEEMRGLRSHMDDLNSENAKLDA--ELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKE---- 2511
Cdd:COG4913    217 MLEEPDTFEAADA----LVEHFDDLERAHEALEDAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQRrlel 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2512 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQ-LTALQEEgtlgvyhaqLKAKEEELQRLNMALSS 2590
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLERE---------IERLERELEERERRRAR 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2591 SQKRTADLEEELVCVQKEATRKVSEIEDQLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLTVTKENKDLM 2670
Cdd:COG4913    364 LEALLAALGLPLPASAEEFAALRAEAAALL------------------EALEEELEALEEALAEAEAALRDLRRELRELE 425

                          250       260
                   ....*....|....*....|....*....
gi 1039751024 2671 AQIQAFGRSMSS----LQDSRDHATEELG 2695
Cdd:COG4913    426 AEIASLERRKSNiparLLALRDALAEALG 454
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1114-1590 4.13e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 4.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1114 ELEGRILDLEKDKTQLQKKLQEAliarKAILKKAQEKekqlKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1193
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1194 ---RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPG-ETAALQATVSVAQIQAQLKEMEVEKEEL 1269
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAhNEEAESLREDADDLEERAEELREEAAEL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1270 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTL---------- 1338
Cdd:PRK02224   369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTArerveeaeal 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1339 ----------QPELDALH-KHMGQKEEEVNYLYGQLSEKEQTLTTVQ------TEMVEQERLIKALHTQLEMQAK---EH 1398
Cdd:PRK02224   449 leagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEerleraEDLVEAEDRIERLEERREDLEEliaER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1399 EERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVES--QVS 1476
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADaeDEI 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1477 VQNQEKDAVLG--------KLTILQEERDKLIAEMDRFLLEN-----QSLSGSCESLKLALGGLTEDKEKLMEELESVRS 1543
Cdd:PRK02224   609 ERLREKREALAelnderreRLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751024 1544 SkMAESTEWQEKHKELQKEYEVLlqsyENVSNEAERIQHVVESVRQE 1590
Cdd:PRK02224   689 E-LEELEELRERREALENRVEAL----EALYDEAEELESMYGDLRAE 730
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1531-3034 4.15e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 49.66  E-value: 4.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1531 KEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV-------LLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTeS 1603
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEenedsihLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1604 DKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL----RAEAQPVggTGESMEALLSSNSSLKEELEKIT 1679
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIystiKSELSKI--YEDDIDALYNELSSIVKENAIDN 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1680 LEHKTlskEFEALMAEKDALSEETRNLklqvEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGK-SQERDALsdsakLED 1758
Cdd:TIGR01612  692 TEDKA---KLDDLKSKIDKEYDKIQNM----ETATVELHLSNIENKKNELLDIIVEIKKHIHGEiNKDLNKI-----LED 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1759 seailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELE--------MEKQKDRELSQALENEKNALLTqISAKD-- 1828
Cdd:TIGR01612  760 ---------FKNKEKELSNKINDYAKEKDELNKYKSKISEIKnhyndqinIDNIKDEDAKQNYDKSKEYIKT-ISIKEde 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1829 -----SELKLLEEE----VTKRTTLNQQIQEELCR--------VTKLKETAEEEKDDLEERLMNQ----LAELNGSIGNY 1887
Cdd:TIGR01612  830 ifkiiNEMKFMKDDflnkVDKFINFENNCKEKIDSeheqfaelTNKIKAEISDDKLNDYEKKFNDskslINEINKSIEEE 909

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1888 YQDVTDAQIKNEQLE---------SEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY----------MEKIQGAQKGP 1948
Cdd:TIGR01612  910 YQNINTLKKVDEYIKicentkesiEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFdntlidkineLDKAFKDASLN 989

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1949 ANKSHAKELQELLREKQ------------QEVKQLQKDCIRYLERISALEKTVKALEFV-HTESQKDLDVTKGNLAQAVE 2015
Cdd:TIGR01612  990 DYEAKNNELIKYFNDLKanlgknkenmlyHQFDEKEKATNDIEQKIEDANKNIPNIEIAiHTSIYNIIDEIEKEIGKNIE 1069

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2016 HR-----KKAQAELSSFKIL--------LDDTQSEaarvlaDNLKLKKELQSNKESIKSQIKQKDEDL--LRRLEQAEEK 2080
Cdd:TIGR01612 1070 LLnkeilEEAEINITNFNEIkeklkhynFDDFGKE------ENIKYADEINKIKDDIKNLDQKIDHHIkaLEEIKKKSEN 1143

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2081 HRKEKKNMQEKLDALHREKAH---VEETLAEIQVSLTRKDQEmKELQGSLDSTLAQLAAFTKSMSSLQDDRD-------- 2149
Cdd:TIGR01612 1144 YIDEIKAQINDLEDVADKAISnddPEEIEKKIENIVTKIDKK-KNIYDEIKKLLNEIAEIEKDKTSLEEVKGinlsygkn 1222

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2150 ------RVIDEAKKWERRFGDAIQTKEEEV-RLKEENCIALKDQLRQMAIHMEelkITVSRLEHDKEiweSKAQTELQHH 2222
Cdd:TIGR01612 1223 lgklflEKIDEEKKKSEHMIKAMEAYIEDLdEIKEKSPEIENEMGIEMDIKAE---METFNISHDDD---KDHHIISKKH 1296

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2223 QKAYDKLQEENKELT------SQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQEADI 2296
Cdd:TIGR01612 1297 DENISDIREKSLKIIedfseeSDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKL-----NKIKKIIDEVKEYT 1371

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2297 QNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKE--EAIQ---------LAVEELHQQHSKEIKEL-EN 2362
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLIKKIKDDINLEEckSKIESTLDDKDidECIKkikelknhiLSEESNIDTYFKNADENnEN 1451

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2363 LL------------SQEEEENVALEEEN---------KRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSL----- 2416
Cdd:TIGR01612 1452 VLllfkniemadnkSQHILKIKKDNATNdhdfninelKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELlnkys 1531

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2417 -----------QDDRDRIVSDYRQLE----------ERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAK 2475
Cdd:TIGR01612 1532 alaiknkfaktKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK 1611

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2476 LDaelvQYRRDLNEVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSsdalQKEKQGLSKEI 2551
Cdd:TIGR01612 1612 IS----DIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK----KKELDELDSEI 1683

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2552 KNLQTQLTALQEEGTLGVYHA---QLKAKEEELQRLNMALSSSQKR------TADLEeelvcvQKEATRKVSEIEDQLKK 2622
Cdd:TIGR01612 1684 EKIEIDVDQHKKNYEIGIIEKikeIAIANKEEIESIKELIEPTIENlissfnTNDLE------GIDPNEKLEEYNTEIGD 1757

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2623 ELKHLHHDAGIMRNETETAEER---VAELARDLVEMEQKLLTVTKENKDLMA-----QIQAFGRSMSSLQDSRDHA---- 2690
Cdd:TIGR01612 1758 IYEEFIELYNIIAGCLETVSKEpitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVndkf 1837

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2691 TEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHN-QV 2769
Cdd:TIGR01612 1838 TKEYSKINEGFDDISKSIENVKNSTDENLLFDILNK------TKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINiQI 1911

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2770 QSiSKAMTSLQNERDRLWSELE-------KFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNlQQQ 2842
Cdd:TIGR01612 1912 QN-NSGIDLFDNINIAILSSLDsekedtlKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQDTLNIIFEN-QQL 1989

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2843 Y--LQMSQEMTE-LRPLKAQLQESQDQTKALQVMEEELRQENLSWQH--------ELRQLRMEKNSWELHERRMKEQFLM 2911
Cdd:TIGR01612 1990 YekIQASNELKDtLSDLKYKKEKILNDVKLLLHKFDELNKLSCDSQNydtilelsKQDKIKEKIDNYEKEKEKFGIDFDV 2069

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2912 AISDKdqqlgHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTqlndslkEIHQKELRIQQLNS 2991
Cdd:TIGR01612 2070 KAMEE-----KFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNT-------EIKIIEDKIIEKND 2137

                         1690      1700      1710      1720
                   ....*....|....*....|....*....|....*....|....
gi 1039751024 2992 KFSQLLE-EKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKE 3034
Cdd:TIGR01612 2138 LIDKLIEmRKECLLFSYATLVETLKSKVINHSEFITSAAKFSKD 2181
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1567-2231 4.35e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 4.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1567 LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMeemkekmrkfaKSKQQKILELEEENDR 1646
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREI-----------NEISSELPELREELEK 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1647 LRAEaqpvggtgesmeallssnsslKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKS 1726
Cdd:PRK03918   226 LEKE---------------------VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--EKV 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1727 DEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMgdgakpgvsetfSSHDDIKNYLQQLDQLKGRIAELEMEKQKD 1806
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE------------EEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1807 RELSQALEnEKNALLTQISAKDSELKLLEEEVTKRTTlnQQIQEELCRVTKLKETAEEEKDDLEERlmnqlaelngsIGN 1886
Cdd:PRK03918   351 EKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-----------IGE 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1887 YYQDVTDAQIKNEQLESEMRNLQRCVSEL-EEEKQQLVKEKTKVESEIRKEymekiqgaqkgpankshAKELQELLREKQ 1965
Cdd:PRK03918   417 LKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKELLEEYTAELKRIEKE-----------------LKEIEEKERKLR 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1966 QEVKQLQKDcIRYLERISALEKTVKALEFVHTESQKdldvtkgnlaQAVEHRKKAQAELSSFKILLDDTQSEaARVLADN 2045
Cdd:PRK03918   480 KELRELEKV-LKKESELIKLKELAEQLKELEEKLKK----------YNLEELEKKAEEYEKLKEKLIKLKGE-IKSLKKE 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2046 LKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE-TLAEIQVSLTRKDQEMKELQ 2124
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL--EPFYNEYlELKDAEKELEREEKELKKLE 625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2125 GSLDSTLAQLAAFTKSMSSLQDDrdrvIDEAKKweRRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRL 2204
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKE----LEELEK--KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                          650       660
                   ....*....|....*....|....*..
gi 1039751024 2205 EHDKEIWEsKAQTELQHHQKAYDKLQE 2231
Cdd:PRK03918   700 KEELEERE-KAKKELEKLEKALERVEE 725
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 79-972 4.38e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 4.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   79 QQKDEALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGAALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEK 158
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  159 EKLISSLQAQLDQSEQASQLDKSSAEMEDfvLMKQQLQEKEELISTLQTQLSQTQAEQAAQKLRVMQRKLEEHEEALLGR 238
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  239 AQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEvAERKLSFHNLQEEMHQLQGQLER 318
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLE-SERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  319 AGQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQElqsacaalkeenskllqekhdqaaesAQAMRQLEDQLQQKS 398
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQG--------------------------KLTEEKEELEKQELK 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  399 KEISQFVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGAlLLSSGELEELKAENEKLSSRITLL 478
Cdd:pfam02463  460 LLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLA-LIKDGVGGRIISAHGRLGDLGVAV 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  479 EAQNRAGEADGTVcEVSTAGTTLLNRSDSSPEENGQAVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDY 558
Cdd:pfam02463  539 ENYKVAISTAVIV-EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  559 EVLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKSLAVSHV 638
Cdd:pfam02463  618 DDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  639 CQCHQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLtQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV 718
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKL-LKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 LAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQS 798
Cdd:pfam02463  777 AEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKEREVREGTERLRDISQEMEglsqalsqkELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN 878
Cdd:pfam02463  857 ERLEEEITKEELLQELLLKEEELE---------EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  879 EEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKEL 958
Cdd:pfam02463  928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKL 1007

                          890
                   ....*....|....
gi 1039751024  959 LQKVSQLEEELAKV 972
Cdd:pfam02463 1008 IRAIIEETCQRLKE 1021
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1947-2161 4.44e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 4.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1947 GPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSS 2026
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2027 FKILLDDTQSEAARVLA--------DNLKLKKELQSNKESIKS-----QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLD 2093
Cdd:COG4942     95 LRAELEAQKEELAELLRalyrlgrqPPLALLLSPEDFLDAVRRlqylkYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 2094 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2161
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2436-3016 4.47e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2436 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2510
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2511 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2577
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2578 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2651
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2652 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2728
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2729 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2808
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2809 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2888
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2889 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 2966
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 2967 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3016
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1107-1973 4.53e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 4.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1107 GEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQL 1186
Cdd:pfam02463  152 PERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1187 RQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSppGETAALQATVSVAQIQAQLKEMEVEK 1266
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKL--QEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1267 EELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASveaqahTELLKQELESSQLKVAGLEHLKTLQPELDALH 1346
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR------EAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1347 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEhEERLKQAQVEICELKKKPTELEEETNAK 1426
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1427 QQLQRKLQAALISRKEALKENKSLQEQLSSARDAvERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF 1506
Cdd:pfam02463  463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKLE-ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1507 LLENQSL-----------SGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1575
Cdd:pfam02463  542 KVAISTAvivevsatadeVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1576 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVG 1655
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1656 GTGESMEALLSSNSSLKEE---LEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1732
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEellADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1733 IEEVtqavvgKSQERDALSDSAKLEDSEAILMgdgakpgvsetfsSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQA 1812
Cdd:pfam02463  782 KTEK------LKVEEEKEEKLKAQEEELRALE-------------EELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1813 LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsiGNYYQDVT 1892
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL---LEEKENEI 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1893 DAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiQGAQKGPANKSHAKELQELLREKQQEVKQLQ 1972
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL-AKEELGKVNLMAIEEFEEKEERYNKDELEKE 998


                   .
gi 1039751024 1973 K 1973
Cdd:pfam02463  999 R 999
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1300-1719 4.91e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 4.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1300 EIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHmGQKEEEVNYLYGQLSEKEQTLTTVQTEMVE 1379
Cdd:COG4717     89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-EAELAELPERLEELEERLEELRELEEELEE 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1380 QERLIKALHTQLEMQAK----EHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA---LISRKEALKENKSLQE 1452
Cdd:COG4717    168 LEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKE 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1453 QLSSARDAVERLTKSLADVESQVSVQNQEKDAVLG-------------KLTILQEERDKLIAEMDRFLLENQSLSGSCES 1519
Cdd:COG4717    248 ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAA 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1520 LKLALGGLTEDKEKLMEELESVRSS-KMAESTEWQEKHKELQKEYEVLLQSYeNVSNEAERIQHVVESvrQEKQELYAKL 1598
Cdd:COG4717    328 LGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEEL 404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1599 RSTESDKREREKQLQDAEQEMEEMKEKMRkfAKSKQQKILELEEENDRLRAEaqpVGGTGESMEALLSSN--SSLKEELE 1676
Cdd:COG4717    405 EELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEELEELREE---LAELEAELEQLEEDGelAELLQELE 479

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1039751024 1677 KITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQAS 1719
Cdd:COG4717    480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2383-2601 6.33e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 6.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2383 EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsailekdqlIQDAAAENNKLKEEMRGL 2462
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-----------LAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2463 RSHMDDLNSENAKLDAELVQYRR--DLNEVIAIKDSQQ--------KQLLDAQLQQNKELRNECTKLEERLKGLEAEKQS 2532
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024 2533 LQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEE 2601
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKE--LAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1544-2113 7.65e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 7.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1544 SKMAESTEwQEKHKELQKEYEVllqsyeNVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEmeemk 1623
Cdd:PRK02224   213 SELAELDE-EIERYEEQREQAR------ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE----- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1624 ekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEF--EALMAEKDALSE 1701
Cdd:PRK02224   281 ------VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHneEAESLREDADDL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1702 ETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVtqavvgksqERDALSDSAKLEDSEAILmgDGAKPGVSETFSSHDD 1781
Cdd:PRK02224   355 EERAEELREEAAELESELEEAREAVEDRREEIEEL---------EEEIEELRERFGDAPVDL--GNAEDFLEELREERDE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1782 IKNYLQQLD----QLKGRIAELE--MEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRV 1855
Cdd:PRK02224   424 LREREAELEatlrTARERVEEAEalLEAGKCPECGQPVEGSPHV--ETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1856 TKLKETA------EEEKDDLEERLMNQLAELNgsignyyQDVTDAQIKNEQ---LESEMRNLQRCVSELEEEKQQlVKEK 1926
Cdd:PRK02224   502 EDLVEAEdrierlEERREDLEELIAERRETIE-------EKRERAEELRERaaeLEAEAEEKREAAAEAEEEAEE-AREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1927 TKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESqkdldvt 2006
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA------- 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2007 kgNLAQAVEHRKKAQAELSSFKILLDDTQSEaarvladnlklKKELQSNKESIKSQIKQKdEDLLRRLEQAEEKHrkekk 2086
Cdd:PRK02224   647 --RIEEAREDKERAEEYLEQVEEKLDELREE-----------RDDLQAEIGAVENELEEL-EELRERREALENRV----- 707

                          570       580
                   ....*....|....*....|....*..
gi 1039751024 2087 nmqEKLDALHREKAHVEETLAEIQVSL 2113
Cdd:PRK02224   708 ---EALEALYDEAEELESMYGDLRAEL 731
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2645-2999 8.29e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 8.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2645 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELaqLKEWQDSSREgdvl 2724
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEL--LKEKEALERQ---- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2725 sqaafpLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSlqNERDRLWSELEKFrkseEGKQRAA 2804
Cdd:TIGR02169  239 ------KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGEL----EAEIASL 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2805 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL----QQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQE 2880
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELereiEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2881 NLSWQHELRQLRMEKNSWELHERRM---KEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDG 2957
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1039751024 2958 SQKLVYEtelLRTQLNDSLKEIHQKELRIQQLNSKFSQLLEE 2999
Cdd:TIGR02169  467 YEQELYD---LKEEYDRVEKELSKLQRELAEAEAQARASEER 505
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
643-1002 8.61e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 8.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  643 QGELERLKTQVLELETSLHTAEETYKRNLsekvKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV-LAE 721
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLR----EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEeIEE 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  722 LRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 801
Cdd:PRK02224   396 LRERFGDAPVDLGNAEDFL----EELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIE 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  802 AKEREVREGTERLRDISQEMEGLSQALSQKE--LEIAKMDQLLLEKQKDVETL-----------QQTIQEKDQQVTELSF 868
Cdd:PRK02224   472 EDRERVEELEAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELiaerretieekRERAEELRERAAELEA 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  869 SMTEKMVQ---LNEEKFSLGVEIKTLKEQLNLLSRTEEATkEQVEESGAGSSLKLGHDESGQEGLQQ--ELELLRKE--S 941
Cdd:PRK02224   552 EAEEKREAaaeAEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREAlaELNDERRErlA 630

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024  942 EQRKRK--------------LQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEE 1002
Cdd:PRK02224   631 EKRERKreleaefdearieeAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN 705
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1804-2654 1.09e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1804 QKDRELSQALENEKNAlltqisakDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEekddLEERLMNQLAELNGS 1883
Cdd:pfam01576    9 AKEEELQKVKERQQKA--------ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE----MRARLAARKQELEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1884 IGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEE-------KQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKE 1956
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQldeeeaaRQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1957 LQEL-------LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKI 2029
Cdd:pfam01576  157 LEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRA 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2030 LLDDTQSEAARVLA---DNLKLKKELQSNKESIKSQIKQKDEDLLRRlEQAEEKHRKEKKNMQEKLDALHREKAHVEETL 2106
Cdd:pfam01576  237 QLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTLDTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2107 AEIQVSLTRKDQEMKELQGSLDSTL----AQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE-------EVRL 2175
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2176 KEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWE---SKAQTELQHHQKAYD-------KLQEENKELTSQLEDARQ 2245
Cdd:pfam01576  396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELESVSSLLNeaegkniKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2246 LYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEIN 2325
Cdd:pfam01576  476 LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2326 AKEQkiisllsgKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKR--------ALEKT--NQLTEALEAI 2395
Cdd:pfam01576  556 ALTQ--------QLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqkkfdqmlAEEKAisARYAEERDRA 627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2396 KKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDDLN-- 2470
Cdd:pfam01576  628 EAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknVHELERSKRALEQQVEEMKTQLEELEde 707

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2471 ---SENAKLDAEL------VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERL---KGLEAEKQSLQMSSD 2538
Cdd:pfam01576  708 lqaTEDAKLRLEVnmqalkAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVaakKKLELDLKELEAQID 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2539 ALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaqlkAKEEELQRLNMALSS--SQKRTADLEEELVCVQKE------AT 2610
Cdd:pfam01576  788 AANKGREEAVKQLKKLQAQMKDLQRE-----------LEEARASRDEILAQSkeSEKKLKNLEAELLQLQEDlaaserAR 856

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 1039751024 2611 RKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2654
Cdd:pfam01576  857 RQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1115-1934 1.15e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.12  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1115 LEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE-KEKQLKEELREQKDAYHHLQGQFHEQ---NKEKENIADQLRQLQ 1190
Cdd:TIGR00606  274 LKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHnHQRTVREKERELVDCQRELEKLNKERrllNQEKTELLVEQGRLQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1191 CQARESIDRQLPGTGQQEPGPPAPSLEGISlEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELE 1270
Cdd:TIGR00606  354 LQADRHQEHIRARDSLIQSLATRLELDGFE-RGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIR 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1271 LKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEA-QAHTELLKQELESSQL--------KVAGLEHLKTLQPE 1341
Cdd:TIGR00606  433 DEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIlELDQELRKAERELSKAeknsltetLKKEVKSLQNEKAD 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1342 LDALHKHMGQKEEEVNYLYGQLSEKEqTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE 1421
Cdd:TIGR00606  513 LDRKLRKLDQEMEQLNHHTTTRTQME-MLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRD 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1422 ETnakQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSlADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1501
Cdd:TIGR00606  592 RL---AKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQ 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1502 EMDRFLLENQSLSGSCESLKLALGGLTEdkekLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1581
Cdd:TIGR00606  668 FITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1582 HVVESVRQEKQELYAKLRSTESDKREREKQLQ--DAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTgE 1659
Cdd:TIGR00606  744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtiMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLD-R 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1660 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKlqVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1739
Cdd:TIGR00606  823 TVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELK--SEKLQIGTNLQRRQQFEEQLVELSTEVQSL 900

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1740 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQ--KDRELSQAlENEK 1817
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQdgKDDYLKQK-ETEL 979

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1818 NALLTQISAKDSELKLLEEEV--TKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyYQDVTDAQ 1895
Cdd:TIGR00606  980 NTVNAQLEECEKHQEKINEDMrlMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG------QMQVLQMK 1053

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1039751024 1896 IKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIR 1934
Cdd:TIGR00606 1054 QEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
46 PHA02562
endonuclease subunit; Provisional
 2484-2713 1.19e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2484 RRDLNE------VIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQG----LSKEIKN 2553
Cdd:PHA02562   152 RRKLVEdlldisVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKT 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2554 LQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALS--SSQKRTADLEEEL--------VCVQK---------EATRKVS 2614
Cdd:PHA02562   232 IKAEIEELTDE--LLNLVMDIEDPSAALNKLNTAAAkiKSKIEQFQKVIKMyekggvcpTCTQQisegpdritKIKDKLK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2615 EIEDQLKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQafgrsmsSLQDSRDHATEEL 2694
Cdd:PHA02562   310 ELQHSLEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEEL 381

                          250
                   ....*....|....*....
gi 1039751024 2695 GDLKKKYDASLKELAQLKE 2713
Cdd:PHA02562   382 AKLQDELDKIVKTKSELVK 400
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1548-2122 1.24e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1548 ESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMR 1627
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1628 KFAKSKQQKI-----LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEE 1702
Cdd:TIGR00618  350 LHSQEIHIRDahevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1703 TRNLKLQVEAQVLKQASLEATEKSDEPKDV--------IEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSE 1774
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITCTAQCEKLEKIhlqesaqsLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1775 TFSSHDDIKNYLQ------QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQI 1848
Cdd:TIGR00618  510 CIHPNPARQDIDNpgpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1849 QEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEM---RNLQRCVSELEEEKQQLVKE 1925
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTalhALQLTLTQERVREHALSIRV 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1926 KTKVESEIRKEYMEKIQG-AQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLD 2004
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSeKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2005 VTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKE 2084
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1039751024 2085 KKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKE 2122
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQE 867
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 123-346 1.51e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  123 AALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDfvlMKQQLQEKEELI 202
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER--RIAALARRIRA---LEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  203 STLQTQLSQTQAEQAAQK------LRVMQRKLEEHEEALLG----------RAQVVDLLQKELTSAEQRNQVLSQQLQLL 266
Cdd:COG4942     86 AELEKEIAELRAELEAQKeelaelLRALYRLGRQPPLALLLspedfldavrRLQYLKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  267 EAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTA 346
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK11281 PRK11281
mechanosensitive channel MscK;
2227-2590 1.69e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2227 DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDlNNSLEKckehennLEGIIKQQEADIQNCKFSCEQL 2306
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLS-TLSLRQ-------LESRLAQTLDQLQNAQNDLAEY 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2307 ETDLAASRELTSRLHDEINA---KEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQeeeenvaleeeNKRALE 2383
Cdd:PRK11281   148 NSQLVSLQTQPERAQAALYAnsqRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDL-----------QRKSLE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2384 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSD--YRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRG 2461
Cdd:PRK11281   217 GNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEktVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2462 LRSHMDDLNSENAK----LDaELVQYRRDLNEVI-AIKDS--------QQKQLLdAQLQQNKELRNECTKLeeRLKGLEA 2528
Cdd:PRK11281   297 ATEKLNTLTQQNLRvknwLD-RLTQSERNIKEQIsVLKGSlllsrilyQQQQAL-PSADLIEGLADRIADL--RLEQFEI 372

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 2529 EKQSLQMSSDA------LQKEKQGLSKEIKNlqtQLTALqeegtlgvyhaqLKAKEEELQRLNMALSS 2590
Cdd:PRK11281   373 NQQRDALFQPDayidklEAGHKSEVTDEVRD---ALLQL------------LDERRELLDQLNKQLNN 425
PRK11281 PRK11281
mechanosensitive channel MscK;
1336-1513 1.77e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1336 KTLQPELDALHKHmGQKEEEVNYLYGQLsekEQTLTTV-QTEMVEQErlikalHTQLEMQAKEHEERLKQAQVEICELKK 1414
Cdd:PRK11281    39 ADVQAQLDALNKQ-KLLEAEDKLVQQDL---EQTLALLdKIDRQKEE------TEQLKQQLAQAPAKLRQAQAELEALKD 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1415 KPTELEEETNAKQ---QLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLAdvESQVSVQ---NQEKDAVLGK 1488
Cdd:PRK11281   109 DNDEETRETLSTLslrQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY--ANSQRLQqirNLLKGGKVGG 186

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1039751024 1489 LTILQEERDKLIAEMD---------RFLLENQSL 1513
Cdd:PRK11281   187 KALRPSQRVLLQAEQAllnaqndlqRKSLEGNTQ 220
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
684-1075 1.83e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  684 LSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSI 763
Cdd:PRK02224   277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  764 EAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLL 843
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  844 EKQKDVETLQQ---------------------TIQEKDQQVTELSFSMTEKMVQLN--EEKFSLGVEIKTLKEQLNLLSR 900
Cdd:PRK02224   437 TARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEevEERLERAEDLVEAEDRIERLEE 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  901 TEEATKEQVEESGAGsslkLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE------ 974
Cdd:PRK02224   517 RREDLEELIAERRET----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriesle 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  975 DSRKEIPFGENERRKLEEDRENRDDPEEWGTSKwREVEASLKQTISEKEVELEGirrdlkektAAEEELQAVVQRMTRDL 1054
Cdd:PRK02224   593 RIRTLLAAIADAEDEIERLREKREALAELNDER-RERLAEKRERKRELEAEFDE---------ARIEEAREDKERAEEYL 662

                          410       420
                   ....*....|....*....|.
gi 1039751024 1055 QSKTKQIDLLQEEVTENQATI 1075
Cdd:PRK02224   663 EQVEEKLDELREERDDLQAEI 683
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2474-2704 1.86e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2474 AKLDAELVQYRRDLNEVIAikdsQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2553
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIA----ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2554 LQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQK-RTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAG 2632
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2633 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDAS 2704
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2498-2717 1.94e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2498 QKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAK 2577
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE------LAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2578 EEELQRlnmalsSSQKRTADLEEELVCVQKeaTRKVSEIEDQLK-KELKHLHHDAGIMRNETETAEERVAELARDLVEME 2656
Cdd:COG4942     92 IAELRA------ELEAQKEELAELLRALYR--LGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 2657 QKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDS 2717
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1318-1602 1.94e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 1.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1318 LKQELES--SQLKVAGLEHLKTLQPELDA-----LHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQErlikalhtq 1390
Cdd:PRK05771    14 LKSYKDEvlEALHELGVVHIEDLKEELSNerlrkLRSLLTKLSEALDKL-RSYLPKLNPLREEKKKVSVKS--------- 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1391 LEMQAKEHEERLKQAQVEICELKKKPTELEEEtnaKQQLQRKLQAALISRK-----EALKENKSLQEQLSSARDAVERLT 1465
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENE---IKELEQEIERLEPWGNfdldlSLLLGFKYVSVFVGTVPEDKLEEL 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1466 KSLADVESQVSV-QNQEKDAVLgkLTILQEERDKLIAEMDRFLLENQSLSGScESLKLALGGLTEDKEKLMEELESVRss 1544
Cdd:PRK05771   161 KLESDVENVEYIsTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL-- 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024 1545 kmaestewqEKHKELQKEYE-VLLQSYENVSNEAERiqhvvesvrqekQELYAKLRSTE 1602
Cdd:PRK05771   236 ---------EELKELAKKYLeELLALYEYLEIELER------------AEALSKFLKTD 273
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
771-986 1.97e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  771 KIEALQRELDGVQLQFCEQGTQMKTLQSQLEA--KEREVREGTERLRDISQEMEGLSQALSQKELEIAKmdqlLLEKQKD 848
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  849 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGsslklghdesGQE 928
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL----------ARL 745

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751024  929 GLQQELELLRKESEQRK--RKLQAALINRKELLQ-KVSQLEEELAKVREDSRKEIPFGENE 986
Cdd:COG4913    746 ELRALLEERFAAALGDAveRELRENLEERIDALRaRLNRAEEELERAMRAFNREWPAETAD 806
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
646-828 2.08e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  646 LERLKTQVLELETSLHTAEETYK------RNLSEKVKEISSLTQLSEEVKESAEeARSTLAAVTEERDQLLyqvKELDVL 719
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEaleaelDALQERREALQRLAEYSWDEIDVAS-AEREIAELEAELERLD---ASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  720 AELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgtqmKTLQSQ 799
Cdd:COG4913    688 AALEEQLEELEAELEELEEEL----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE----RFAAAL 759

                          170       180       190
                   ....*....|....*....|....*....|
gi 1039751024  800 LEAKEREVREG-TERLRDISQEMEGLSQAL 828
Cdd:COG4913    760 GDAVERELRENlEERIDALRARLNRAEEEL 789
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1266-1710 2.21e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 2.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1266 KEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDA 1344
Cdd:TIGR04523  220 ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEkQLNQLKSEISD 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1345 LHKhmgQKEEEVN-YLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEET 1423
Cdd:TIGR04523  300 LNN---QKEQDWNkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1424 NAKQQLQRKLQaALISRKEAL--------KENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEE 1495
Cdd:TIGR04523  377 KENQSYKQEIK-NLESQINDLeskiqnqeKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1496 RDKLIAEMDRFLLENQSLSGSCESLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1575
Cdd:TIGR04523  456 IKNLDNTRESLETQLKVLSRSINKIKQNL----EQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1576 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSKQQKILELEEENDRLRAEaqpvg 1655
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQ--EEKQELIDQKEKEKKDLIKE----- 604

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 1656 gtgesMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQV 1710
Cdd:TIGR04523  605 -----IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 766-1047 2.24e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  766 KSKDVKIEALQrELDGVQLQFCEQGTQMKTLqSQLEAKEREVREGTERLRDISQEmEGLSQALsQKELEIAKMDQLLLEK 845
Cdd:PRK05771    16 SYKDEVLEALH-ELGVVHIEDLKEELSNERL-RKLRSLLTKLSEALDKLRSYLPK-LNPLREE-KKKVSVKSLEELIKDV 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  846 QKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF------SLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslk 919
Cdd:PRK05771    92 EEELEKIEKEIKELEEEISEL----ENEIKELEQEIErlepwgNFDLDLSLLLGFKYVSVFVGTVPEDKLEELKL----- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  920 lghdESGQEGLqqelellrKESEQRKRKLQAALINRKELLQKVsqlEEELAKVrEDSRKEIPfgenerrkleedrenrdd 999
Cdd:PRK05771   163 ----ESDVENV--------EYISTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE------------------ 208

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751024 1000 peEWGTSKwrEVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1047
Cdd:PRK05771   209 --EEGTPS--ELIREIKEELEEIEKERESLLEELKELAKKYLEELLAL 252
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1244-1469 2.39e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1244 AALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1323
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1324 SSQLKVAGLEHLktLQPELDALHKHMGQKEEEV---NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEE 1400
Cdd:COG4942     94 ELRAELEAQKEE--LAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024 1401 RLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLA 1469
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1450-2002 2.61e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 2.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1450 LQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTE 1529
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1530 DKEK------LMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVrQEKQELYAKLRSTES 1603
Cdd:PRK01156   268 ELEKnnyykeLEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL-SVLQKDYNDYIKKKS 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1604 DKREREKQLQDAEQEMEEMKEKMRKFaKSKQQKILELEEENDRLRAEAQPVGGTGE-SMEALLSSNSSLKEELEKITLEH 1682
Cdd:PRK01156   347 RYDDLNNQILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEiDPDAIKKELNEINVKLQDISSKV 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1683 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLkqASLEATEKSdepKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAI 1762
Cdd:PRK01156   426 SSLNQRIRALRENLDELSRNMEMLNGQSVCPVC--GTTLGEEKS---NHIINHYNEKKSRLEEKIREIEIEVKDIDEKIV 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1763 LMGDgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQAlENEKNALLTQISAKDseLKLLEEEVTKRT 1842
Cdd:PRK01156   501 DLKK------RKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDK-HDKYEEIKNRYKSLK--LEDLDSKRTSWL 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1843 TLNQQIQE-ELCRVTKLKETAEEEKDDLEERLM--------------NQLAELNGSIGNY---YQDVTDAQIKNEQLESE 1904
Cdd:PRK01156   572 NALAVISLiDIETNRSRSNEIKKQLNDLESRLQeieigfpddksyidKSIREIENEANNLnnkYNEIQENKILIEKLRGK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1905 MRNLQRCVSELEEEKQQLvKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISA 1984
Cdd:PRK01156   652 IDNYKKQIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730

                          570
                   ....*....|....*...
gi 1039751024 1985 LEKTVKALEFVHTESQKD 2002
Cdd:PRK01156   731 IKKAIGDLKRLREAFDKS 748
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1379-1651 2.68e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1379 EQERLIKALHtqlEMQAkeheerlkqaqVEICELKKKptELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSAR 1458
Cdd:PRK05771    17 YKDEVLEALH---ELGV-----------VHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1459 -----DAVERLTKSLADVESQVSVQNQEkdavlgkLTILQEERDKLIAEMDR------FLLENQSLSGScESLKLALGGL 1527
Cdd:PRK05771    81 vksleELIKDVEEELEKIEKEIKELEEE-------ISELENEIKELEQEIERlepwgnFDLDLSLLLGF-KYVSVFVGTV 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1528 TEDKEKLMEELESVRSSKMAESTEwqEK-------HKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrs 1600
Cdd:PRK05771   153 PEDKLEELKLESDVENVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------ 224

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 1601 tesdkREREKQLQDAEqemeemkEKMRKFAKSKQQKILELEE--ENDRLRAEA 1651
Cdd:PRK05771   225 -----EEIEKERESLL-------EELKELAKKYLEELLALYEylEIELERAEA 265
PTZ00121 PTZ00121
MAEBL; Provisional
 647-1161 3.29e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  647 ERLKTQVLELETSLHTAEETYKrnlSEKVKEISSLTQLSEEVKEsAEEARSTLAAVTEERDQLLYQVKELDVLAELRARV 726
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKK---AEEKKKADEAKKKAEEAKK-ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE 1351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  727 QELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKD---VKIEALQRELDGVQlqfceQGTQMKTLQSQLEAK 803
Cdd:PTZ00121  1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELK-----KAAAAKKKADEAKKK 1426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  804 EREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKdQQVTELSFSMTEKMVQLNEEKfs 883
Cdd:PTZ00121  1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA-KKADEAKKKAEEAKKKADEAK-- 1503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  884 lgvEIKTLKEQLNLLSRTEEATK----EQVEESGAGSSLKLGHDESGQEGLQQELEL-----------LRKESEQRKRKL 948
Cdd:PTZ00121  1504 ---KAAEAKKKADEAKKAEEAKKadeaKKAEEAKKADEAKKAEEKKKADELKKAEELkkaeekkkaeeAKKAEEDKNMAL 1580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  949 QAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEG 1028
Cdd:PTZ00121  1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1029 IRRDLKEKTAAEEELQA-VVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAAPVKETAASSPPGAGG 1107
Cdd:PTZ00121  1661 IKAAEEAKKAEEDKKKAeEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 1108 EEHWKPElEGRILDLEKDKTQLQKKLQEaliarKAILKKAQEKEKQLKEELREQ 1161
Cdd:PTZ00121  1741 EDKKKAE-EAKKDEEEKKKIAHLKKEEE-----KKAEEIRKEKEAVIEEELDEE 1788
46 PHA02562
endonuclease subunit; Provisional
 2206-2426 3.33e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 3.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2206 HDKEIWESKAQT--ELQHHQKAYDKLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2283
Cdd:PHA02562   200 YNKNIEEQRKKNgeNIARKQNKYDELVEEAKTIKAEIEEL-------TDELLNLVMDIEDPSAALNKLNTAAAKIKSKIE 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2284 NLEGIIKQQEaDIQNCKfSCEQletDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQhsKEIKELENL 2363
Cdd:PHA02562   273 QFQKVIKMYE-KGGVCP-TCTQ---QISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQS--KKLLELKNK 345

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 2364 LSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR--IVSD 2426
Cdd:PHA02562   346 ISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHrgIVTD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2614-2837 3.52e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2614 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEE 2693
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2694 LGDLKKKYDASLKELAQLkewQDSSREGDVLSQAAFplSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSIS 2773
Cdd:COG4942     99 LEAQKEELAELLRALYRL---GRQPPLALLLSPEDF--LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 2774 KAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELK 2837
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1277-1446 3.53e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1277 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELES--SQLKVAGLEHLKTLQPELDALHKHMGQKEE 1354
Cdd:COG4913    280 ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEleAQIRGNGGDRLEQLEREIERLERELEERER 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1355 EVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQ 1434
Cdd:COG4913    360 RRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP 439

                          170
                   ....*....|..
gi 1039751024 1435 AALISRKEALKE 1446
Cdd:COG4913    440 ARLLALRDALAE 451
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1669-1880 4.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1669 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1746
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1747 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1822
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 1823 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1880
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2010-2563 4.65e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.98  E-value: 4.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2010 LAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMq 2089
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSEL- 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2090 EKLDALHR-------EKAHVE-ETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS--------LQDDRDRVID 2153
Cdd:pfam12128  325 EALEDQHGafldadiETAAADqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqnnrdiagIKDKLAKIRE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2154 EAKKWERRFGDAIQTKEEEVRLKEENCIA-LKDQLRQMAIHMEELKITV------SRLEHDKEIWES---KAQTELQHHQ 2223
Cdd:pfam12128  405 ARDRQLAVAEDDLQALESELREQLEAGKLeFNEEEYRLKSRLGELKLRLnqatatPELLLQLENFDErieRAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2224 KAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQ---------------------------------TTD 2270
Cdd:pfam12128  485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtllhflrkeapdweqsigkvispellhRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2271 LNNSL-EKCKEHENNLEGI-IKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAIQLAVEE 2348
Cdd:pfam12128  565 LDPEVwDGSVGGELNLYGVkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ-LVQANGELEKASREETF 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2349 LHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYR 2428
Cdd:pfam12128  644 ARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA-------QLKQLDKKHQAWLEEQKEQKREARTEK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2429 QLEERHLSAILEK--DQLIQDAAAENNKLKEEMRGLRSHMD--------------DLNSENAKLDAELVQYRRDLNEVIA 2492
Cdd:pfam12128  717 QAYWQVVEGALDAqlALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQEVLR 796

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 2493 IKDSQQKQLL---DAQLQQNKELRNECTKLEERLKGLEAE----KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE 2563
Cdd:pfam12128  797 YFDWYQETWLqrrPRLATQLSNIERAISELQQQLARLIADtklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2306-2786 5.03e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 5.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2306 LETDLAASRELTSRLHDE-INAKEQKiisllsgkeEAIQLAVEElHQQHSKEIKELENLLSQEEEENVALEEENKRALEK 2384
Cdd:PRK02224   211 LESELAELDEEIERYEEQrEQARETR---------DEADEVLEE-HEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2385 TNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRS 2464
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR----LEECRVAAQAHNEEAESLREDADDLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2465 HMDDLNSENAKLDAELVQYRRDLNEviaikdsqqkqlldaQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2544
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVED---------------RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2545 QGLSKEIKNLQTQLT----------ALQEEG--------------------------TLGVYHAQLKAKEEEL-QRLNMA 2587
Cdd:PRK02224   422 DELREREAELEATLRtarerveeaeALLEAGkcpecgqpvegsphvetieedrerveELEAELEDLEEEVEEVeERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2588 --LSSSQKRTADLEE------ELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2659
Cdd:PRK02224   502 edLVEAEDRIERLEErredleELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2660 LTVTKEN------KDLMAQIQAFGRSMSSLQDSRDHATeELGDLKKKYdasLKELAQLKEWQDSSREGDVLSQAAFPLST 2733
Cdd:PRK02224   582 AELKERIesleriRTLLAAIADAEDEIERLREKREALA-ELNDERRER---LAEKRERKRELEAEFDEARIEEAREDKER 657

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 2734 SENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRL 2786
Cdd:PRK02224   658 AEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1543-2002 5.25e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 5.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1543 SSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--ELYAKLRSTESDKREREKQLQDAEQEME 1620
Cdd:COG4717     77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERLE 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1621 EMkekmrkfaKSKQQKILELEEENDRLRAEAQpvggtgesmEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALS 1700
Cdd:COG4717    157 EL--------RELEEELEELEAELAELQEELE---------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1701 EETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHD 1780
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1781 DIknylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK--- 1857
Cdd:COG4717    300 LG----KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaal 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1858 LKETAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEK 1926
Cdd:COG4717    376 LAEAGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREEL 455

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 1927 TKVESEIRkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQkdciRYLERISALEKTVKALEFVHTESQKD 2002
Cdd:COG4717    456 AELEAELE---------------QLEEDGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREE 512
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1894-2348 5.34e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 5.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1894 AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRkEYMEKIQGAQkgpankshAKELQELlrekQQEVKQLQK 1973
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELD-ELEAQIRGNG--------GDRLEQL----EREIERLER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1974 DCIRYLERISALEKTVKALEFVHTESQKDLdvtKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQ 2053
Cdd:COG4913    353 ELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAAALLEALEEELEA----LEEALAEAEAALRDLRRELRELE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2054 SNKESI---KSQIKQKDEDLLRRLEQA-----------------------------------------EEKHRK------ 2083
Cdd:COG4913    426 AEIASLerrKSNIPARLLALRDALAEAlgldeaelpfvgelievrpeeerwrgaiervlggfaltllvPPEHYAaalrwv 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2084 EKKNMQEKLDALHREKAHVEETLAEIQV-SLTRK-DQEMKELQGSLDSTLAQLAAFTK--SMSSLQDDRDRV-------- 2151
Cdd:COG4913    506 NRLHLRGRLVYERVRTGLPDPERPRLDPdSLAGKlDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRHPRAItragqvkg 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2152 ------IDEAKKWERR--FG----DAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK----- 2214
Cdd:COG4913    586 ngtrheKDDRRRIRSRyvLGfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvas 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2215 AQTELQHHQKAYDKLQEEN---KELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQ 2291
Cdd:COG4913    666 AEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024 2292 QEAdiqnckfscEQLETDLAA--SRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEE 2348
Cdd:COG4913    746 ELR---------ALLEERFAAalGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1347-1884 5.39e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1347 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERL------IKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELE 1420
Cdd:PRK03918   200 KELEEVLREINEISSELPELREELEKLEKEVKELEELkeeieeLEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1421 E------ETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILqE 1494
Cdd:PRK03918   280 EkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL-E 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1495 ERDKLIAEMDRFLLENQSLSG-----SCESLKLALGGLTEDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVL--- 1566
Cdd:PRK03918   359 ERHELYEEAKAKKEELERLKKrltglTPEKLEKELEELEKAKEEIEEEISKIT----ARIGELKKEIKELKKAIEELkka 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1567 ---------LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1637
Cdd:PRK03918   435 kgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKK 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1638 LELEEendrLRAEAQPVGGTGESMEALLSSNSSLKEELEKItlehKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQ 1717
Cdd:PRK03918   515 YNLEE----LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFES 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1718 ASlEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgDGAKPGVSETFSSHDDIKNYLQQLDQL--KGR 1795
Cdd:PRK03918   587 VE-ELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-----DKAFEELAETEKRLEELRKELEELEKKysEEE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1796 IAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQ---EELCRVTKLKETAEEEKDDLEER 1872
Cdd:PRK03918   661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEkleKALERVEELREKVKKYKALLKER 740

                          570
                   ....*....|..
gi 1039751024 1873 LMNQLAELNGSI 1884
Cdd:PRK03918   741 ALSKVGEIASEI 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1331-2144 5.53e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 5.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1331 GLEHLKTLQPELDALHKHMGQKEEEVNYLY-GQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEI 1409
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESNELHeKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1410 CELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDaverltKSLADVESQVSVQNQEKDAVLGKl 1489
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG------KKIYEHDSMSTMHFRSLGSAISK- 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1490 tILQEERDKLIAEMDR-FLLENQSLSGSCES---LKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV 1565
Cdd:pfam15921  225 -ILRELDTEISYLKGRiFPVEDQLEALKSESqnkIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1566 LLQSYENVSNEAERIQHVVES-VRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKS------------ 1632
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLEStVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQEsgnlddqlqkll 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1633 ----KQQKILELEEENDRLRAEAQpvggTGESMeallsSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKL 1708
Cdd:pfam15921  384 adlhKREKELSLEKEQNKRLWDRD----TGNSI-----TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1709 QVEAQVLKQASLEATEKSDEP--KDVIEEVT-QAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvSETFSSHDDIKny 1785
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEmlRKVVEELTaKKMTLESSERTVSDLTASLQEKERAIEATNAE---ITKLRSRVDLK-- 529

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1786 LQQLDQLKGRIAELemekqkdrelsQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQiqeelcrVTKLKETAEEE 1865
Cdd:pfam15921  530 LQELQHLKNEGDHL-----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-------HGRTAGAMQVE 591

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1866 KDDLEERLMNQLAELNgsignyyqdvtDAQIKNEQLESEMRNLQRCVSELEEEKQQLV---KEKTKVESEIRKEYMEKIQ 1942
Cdd:pfam15921  592 KAQLEKEINDRRLELQ-----------EFKILKDKKDAKIRELEARVSDLELEKVKLVnagSERLRAVKDIKQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1943 GAQKGPANKSHAKELQELL----REKQQEVKQLQKDCIRYLERI-SALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2017
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQLKSAqSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2018 KKAQAELSSFKILLDDTQSeaARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDalhr 2097
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTN--ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD---- 814

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 2098 eKAHVEetLAEIQVSLTRKDQE-----------MKELQG-------SLDSTLAQLAAFTKSMSSL 2144
Cdd:pfam15921  815 -KASLQ--FAECQDIIQRQEQEsvrlklqhtldVKELQGpgytsnsSMKPRLLQPASFTRTHSNV 876
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1788-2277 5.79e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.50  E-value: 5.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1788 QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKD 1867
Cdd:pfam05557   10 RLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1868 DLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmrnLQRCVSELEEEKQQLVKEKTKVEseirkEYMEKIQGAQKG 1947
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQIQRAELE---LQSTNSELEELQERLDLLKAKAS-----EAEQLRQNLEKQ 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1948 P-ANKSHAKELQELLREKQQEV--KQLQKDCIRYLERISALEKTVKALEfvhtESQKDLDVTKGNLAQAVEHRKKAQAEL 2024
Cdd:pfam05557  162 QsSLAEAEQRIKELEFEIQSQEqdSEIVKNSKSELARIPELEKELERLR----EHNKHLNENIENKLLLKEEVEDLKRKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2025 SSFkillDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHV 2102
Cdd:pfam05557  238 ERE----EKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlrSPEDLSRRIEQLQ----QREIVLKEENSSLTSSARQL 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2103 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWerrfgDAIQTKEEEVRLKEENCIA 2182
Cdd:pfam05557  310 EKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESY-----DKELTMSNYSPQLLERIEE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2183 LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAydKLQEENKELTSQLEDARQLYHdsknELTKLESELK 2262
Cdd:pfam05557  385 AEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQAL--RQQESLADPSYSKEEVDSLRR----KLETLELERQ 458

                          490
                   ....*....|....*
gi 1039751024 2263 SLKDQTTDLNNSLEK 2277
Cdd:pfam05557  459 RLREQKNELEMELER 473
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
669-1081 7.63e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 7.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  669 RNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAE--KQRGLDYES 746
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEelEERLEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  747 QRAQHNLLTEQIHSLSIEAKskdvkiEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQ 826
Cdd:COG4717    161 LEEELEELEAELAELQEELE------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  827 ALS----QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV----QLNEEKFSLGVEIKTLKEQLNLL 898
Cdd:COG4717    235 ELEaaalEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  899 SRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK-ESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSR 977
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  978 KEIPFGENERRKLEEDRENRDDPEEWGTSKWreVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRD--LQ 1055
Cdd:COG4717    395 EEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLA 472

                          410       420
                   ....*....|....*....|....*.
gi 1039751024 1056 SKTKQIDLLQEEVTENQATIQKLVTG 1081
Cdd:COG4717    473 ELLQELEELKAELRELAEEWAALKLA 498
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 644-1200 8.00e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 8.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  644 GELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL-DVL 719
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLErsiAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELkEEL 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  720 AELRARVQELESSLAE-----AEKQRGLD------YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGV 782
Cdd:TIGR02169  367 EDLRAELEEVDKEFAEtrdelKDYREKLEklkreiNELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  783 QLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE------------------------------ 832
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaraseervrggraveevlkasiqgvhgt 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  833 --------------LEIAKMDQLLLEKQKDVETLQQTIQ-EKDQQVTELSFSMTEKMVQLNEEKfSLGVEIKTLKEQLNL 897
Cdd:TIGR02169  527 vaqlgsvgeryataIEVAAGNRLNNVVVEDDAVAKEAIElLKRRKAGRATFLPLNKMRDERRDL-SILSEDGVIGFAVDL 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  898 L--------------------SRTEEATK------------EQVEESGA--GSSLKLGHDESGQ--------------EG 929
Cdd:TIGR02169  606 VefdpkyepafkyvfgdtlvvEDIEAARRlmgkyrmvtlegELFEKSGAmtGGSRAPRGGILFSrsepaelqrlrerlEG 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  930 LQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEdrenrddpeewgtskwr 1009
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS----------------- 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1010 eveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDL-----QSKTKQIDLLQEEVTENQATIQKLVTGTmd 1084
Cdd:TIGR02169  749 -----LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKL-- 821

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1085 agngGSAAPVKETAASSppgaggeehwKPELEGRILDLEKDKTQLQKKlQEALIARKAilkKAQEKEKQLKEELREQKDA 1164
Cdd:TIGR02169  822 ----NRLTLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKE-IENLNGKKE---ELEEELEELEAALRDLESR 883

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1039751024 1165 YHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQ 1200
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 664-1070 8.53e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.10  E-value: 8.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  664 EETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVK-ELDVLAELRARVQELESSLAEAEKQRGL 742
Cdd:pfam05483  228 EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKlQDENLKELIEKKDHLTKELEDIKMSLQR 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  743 DYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRE-------LDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLR 815
Cdd:pfam05483  308 SMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAkaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  816 DISQEMEGLSQALSQKELEIAKM------DQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGV-EI 888
Cdd:pfam05483  388 KKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTsEE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  889 KTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE--QRKRKLQAALINRKELLQKVSQLE 966
Cdd:pfam05483  468 HYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDiiNCKKQEERMLKQIENLEEKEMNLR 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  967 EELAKVREDSRKEipfGENERRKLEEDRENRDDPEEWGTSKWREVEASlkqtisekEVELEGIRRDLKEKTAAEEELQAV 1046
Cdd:pfam05483  548 DELESVREEFIQK---GDEVKCKLDKSEENARSIEYEVLKKEKQMKIL--------ENKCNNLKKQIENKNKNIEELHQE 616

                          410       420
                   ....*....|....*....|....
gi 1039751024 1047 VQRMTRDLQSKTKQIDLLQEEVTE 1070
Cdd:pfam05483  617 NKALKKKGSAENKQLNAYEIKVNK 640
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1861-2108 1.11e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1861 TAEEEKDDLEERLMN----QLAELNGSIGNYYqdvtdaqikNEQLESEMRNLQRCVSELEEEKQqlvKEKTKVESEIRKE 1936
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNER---------LRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1937 YMEKIQGAQKGPANKShakELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVhtesqKDLDV------TKGNL 2010
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELE-------NEIKELEQEIERLEPW-----GNFDLdlslllGFKYV 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2011 AQAVEHRKKAQAELSS--------------------FKILLDDTQSEAARVLADNLKLKKELQ---------SNKESIKS 2061
Cdd:PRK05771   146 SVFVGTVPEDKLEELKlesdvenveyistdkgyvyvVVVVLKELSDEVEEELKKLGFERLELEeegtpseliREIKEELE 225

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751024 2062 QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhREKAHVEETLAE 2108
Cdd:PRK05771   226 EIEKERESLLEELKELAKKYLEELLALYEYLEIE-LERAEALSKFLK 271
PqiB COG3008
Intermembrane transporter PqiABC subunit PqiB [Cell wall/membrane/envelope biogenesis];
159-243 1.17e-03

Intermembrane transporter PqiABC subunit PqiB [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442245 [Multi-domain]  Cd Length: 542  Bit Score: 44.44  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  159 EKLISSLQAQLDQSE----QASQLDKSSAEMEDFVLMKQQLQEKEELI---------STLQTQLSQTQAE--QAAQKLRV 223
Cdd:COG3008    436 EEIGENLYRTLANLDstlaSASGLLASLNLTQVLPELQDTLASLQKTLaggiglspdSPLYQDLQQALQEltRAARSLRL 515

                           90       100
                   ....*....|....*....|.
gi 1039751024  224 MQRKLEEHEEALL-GRAQVVD 243
Cdd:COG3008    516 LADTLPRHPNSLIfGRPEVKD 536
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 791-995 1.20e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  791 TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSM 870
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  871 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQ 949
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKA-DKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751024  950 AALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRE 995
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1787-1940 1.20e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1787 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKE------ 1860
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1861 ---TAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY 1937
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1039751024 1938 MEK 1940
Cdd:COG1579    177 LAL 179
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 649-1070 1.20e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  649 LKTQVLELE---TSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDvlaelrAR 725
Cdd:TIGR04523  216 LESQISELKkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  726 VQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKE 804
Cdd:TIGR04523  290 LNQLKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  805 REVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSL 884
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK----ETIIKNNSEIKDL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  885 GVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQ 964
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVL-----------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  965 LEEELAKVREDSRKEipfgenERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQ 1044
Cdd:TIGR04523  515 LTKKISSLKEKIEKL------ESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588

                          410       420
                   ....*....|....*....|....*.
gi 1039751024 1045 AVVQRMTRDLQSKTKQIDLLQEEVTE 1070
Cdd:TIGR04523  589 ELIDQKEKEKKDLIKEIEEKEKKISS 614
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1335-1718 1.21e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1335 LKTLQPELDALHKHMGQK---------------------EEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHT---- 1389
Cdd:COG4717     48 LERLEKEADELFKPQGRKpelnlkelkeleeelkeaeekEEEYAELQEELEELEEELEELEAELEELREELEKLEKllql 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1390 --------QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKEN-KSLQEQLSSARDA 1460
Cdd:COG4717    128 lplyqeleALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQR 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1461 VERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF----LLENQSLSGSCESLKLALGGL--------- 1527
Cdd:COG4717    208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaaLLALLGLGGSLLSLILTIAGVlflvlglla 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1528 ---------TEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyakl 1598
Cdd:COG4717    288 llflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL---- 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1599 rSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAqpvggTGESMEALLSSNSSLKEELEKI 1678
Cdd:COG4717    364 -QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL-----GELEELLEALDEEELEEELEEL 437

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1039751024 1679 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQA 1718
Cdd:COG4717    438 EEELEELEEELEELREELAELEAELEQLEEDGELAELLQE 477
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 649-1379 1.24e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  649 LKTQVLELETSLHTAE-ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL--DVLAELRAR 725
Cdd:TIGR02169  216 LLKEKREYEGYELLKEkEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  726 VQELESSLAEAE------KQRGLDYESQRAQhnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQ 799
Cdd:TIGR02169  296 IGELEAEIASLErsiaekERELEDAEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  800 LEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEK------ 873
Cdd:TIGR02169  373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleikk 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  874 -----------MVQLNEEKFSLGVEIKTLKEQLNLLSR---TEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK 939
Cdd:TIGR02169  453 qewkleqlaadLSKYEQELYDLKEEYDRVEKELSKLQRelaEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  940 ESEQRKRKLQAALINRKELL----QKVSQLEEELAKVREDSRKE-IPFGENERRKLEEDRENRD------------DPEE 1002
Cdd:TIGR02169  533 VGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDgvigfavdlvefDPKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1003 WGTSKW--------REVEASLKQTISEKEVELEGirrDLKEKTAA--------------EEELQAVVQRMTRDLQSKTKQ 1060
Cdd:TIGR02169  613 EPAFKYvfgdtlvvEDIEAARRLMGKYRMVTLEG---ELFEKSGAmtggsraprggilfSRSEPAELQRLRERLEGLKRE 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1061 IDLLQEEVTEnqatIQKLVTGTMDAGnggSAAPVKETAASSPPGAGGEEHWKpeLEGRILDLEKDKTQLQKKLQEALIAR 1140
Cdd:TIGR02169  690 LSSLQSELRR----IENRLDELSQEL---SDASRKIGEIEKEIEQLEQEEEK--LKERLEELEEDLSSLEQEIENVKSEL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1141 KAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQ-NKEKENIADQLRQLQCQAREsIDRQLPgtgqqepgppAPSLEGI 1219
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEVSRIEARLRE-IEQKLN----------RLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1220 SLEDTEPASESDLHAAQPSPPGETAALQA-TVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQG 1298
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENlNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1299 LEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYL-----------------YG 1361
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepvnmlaiqeyeevlkrLD 989

                          810
                   ....*....|....*...
gi 1039751024 1362 QLSEKEQTLTTVQTEMVE 1379
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILE 1007
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2573-3016 1.25e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.83  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2573 QLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDL 2652
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQH 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2653 VEMEQKLLTVTKENKDLMAQIQAfgrSMSSLQDSRDHATEELGDLKKKYDA--------SLKELAQLKEWQDSSREGDVL 2724
Cdd:pfam12128  332 GAFLDADIETAAADQEQLPSWQS---ELENLEERLKALTGKHQDVTAKYNRrrskikeqNNRDIAGIKDKLAKIREARDR 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2725 SQAAfplstSENVLSRLE-----KLNQQLTSKDEQLLHLSS---ELESSHNQVQSISKAMTSLQNERDRL---WSELEKF 2793
Cdd:pfam12128  409 QLAV-----AEDDLQALEselreQLEAGKLEFNEEEYRLKSrlgELKLRLNQATATPELLLQLENFDERIeraREEQEAA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2794 RKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRllkeLKNLQQQYLQMSQEMTELRPLKAQLQEsQDQTKAL--- 2870
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSA----LDELELQLFPQAGTLLHFLRKEAPDWE-QSIGKVIspe 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2871 ---------QVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKE---QFLMAISDKDQQLGHLQSLLRELRSSSQAQI 2938
Cdd:pfam12128  559 llhrtdldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRErldKAEEALQSAREKQAAAEEQLVQANGELEKAS 638

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 2939 LSTQYQRQASPETSASLdgsQKLVYETELLRTQLNDSLKEihqkelRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRE 3016
Cdd:pfam12128  639 REETFARTALKNARLDL---RRLFDEKQSEKDKKNKALAE------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKE 707
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 829-1078 1.28e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 44.03  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  829 SQKELEIAKmDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTE-KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKE 907
Cdd:pfam15905   65 SQKNLKESK-DQKELEKEIRALVQERGEQDKRLQALEEELEKVEaKLNAAVREKTSLSASVASLEKQLLELTRVNELLKA 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  908 QVEESGAGSSLKLGHDESGQegLQQELELLRKE----SEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKE---- 979
Cdd:pfam15905  144 KFSEDGTQKKMSSLSMELMK--LRNKLEAKMKEvmakQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEkset 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  980 ------IPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTA-AEEELQAVVQRMTR 1052
Cdd:pfam15905  222 eklleyITELSCVSEQVEKYKLDIAQLEELLKEKNDEIE-SLKQSLEEKEQELSKQIKDLNEKCKlLESEKEELLREYEE 300

                          250       260
                   ....*....|....*....|....*.
gi 1039751024 1053 DLQSKTKQIDLLQEEVTENQATIQKL 1078
Cdd:pfam15905  301 KEQTLNAELEELKEKLTLEEQEHQKL 326
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1013-1218 1.28e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1013 ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAA 1092
Cdd:COG4942     44 AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLA 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1093 PVkeTAASSPPGAGGEEHW----KPELEGRILDLEKDKTQLQKKLQEALIARK---AILKKAQEKEKQLKEELREQKDAY 1165
Cdd:COG4942    124 LL--LSPEDFLDAVRRLQYlkylAPARREQAEELRADLAELAALRAELEAERAeleALLAELEEERAALEALKAERQKLL 201

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 1166 HHLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEG 1218
Cdd:COG4942    202 ARLEKELAELAAELAELQQEAEELE-ALIARLEAEAAAAAERTPAAGFAALKG 253
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 718-1339 1.33e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  718 VLAELRARVQELESSLAEAEKQ-RGLDYESQRAQHNLLteQIHSLSIEAKSKDVKIEalqreLDGVQLQFCEQGTQMKTL 796
Cdd:pfam15921  225 ILRELDTEISYLKGRIFPVEDQlEALKSESQNKIELLL--QQHQDRIEQLISEHEVE-----ITGLTEKASSARSQANSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  797 QSQLEAKEREVREGTerlrdiSQEMEGLSqalsqkELEiAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV- 875
Cdd:pfam15921  298 QSQLEIIQEQARNQN------SMYMRQLS------DLE-STVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTe 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  876 --QLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQ---VEESGAGSSLKLGH-----DESGQE--GLQQELELLRKESEQ 943
Cdd:pfam15921  365 rdQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrLWDRDTGNSITIDHlrrelDDRNMEvqRLEALLKAMKSECQG 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  944 RKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEAS------LKQ 1017
Cdd:pfam15921  445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATnaeitkLRS 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1018 TISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTrdlqSKTKQIDLLQEEVtENQATIQKLVTGTMDAGNGGSAAPVKET 1097
Cdd:pfam15921  525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMA----EKDKVIEILRQQI-ENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1098 ------AASSPPGAGGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAIlkkAQEKEKQLKE------ELREQKDAY 1165
Cdd:pfam15921  600 ndrrleLQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDI---KQERDQLLNEvktsrnELNSLSEDY 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1166 HHLQGQFHEQNKEKENIADQLRqLQCQARESIDRQLPGTGQQEPGPPAPSLE-GISLEDTEPASESDLHAAQpsppGETA 1244
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLK-MQLKSAQSELEQTRNTLKSMEGSDGHAMKvAMGMQKQITAKRGQIDALQ----SKIQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1245 ALQATVSVAqiQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNL-----KAASVEAQAHTELLK 1319
Cdd:pfam15921  752 FLEEAMTNA--NKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQDIIQR 829

                          650       660
                   ....*....|....*....|
gi 1039751024 1320 QELESSQLKVAGLEHLKTLQ 1339
Cdd:pfam15921  830 QEQESVRLKLQHTLDVKELQ 849
PRK12704 PRK12704
phosphodiesterase; Provisional
 1126-1201 1.37e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.38  E-value: 1.37e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024 1126 KTQLQKKLQEALIARKAILKKAQEKEKQLKEE-LREQKDAYHHLQGQFHEQNKEKEN-IADQLRQLQcQARESIDRQL 1201
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEaLLEAKEEIHKLRNEFEKELRERRNeLQKLEKRLL-QKEENLDRKL 102
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
797-1036 1.42e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  797 QSQLEAKEREVREGTERLRDISQEMEGLSQALS--QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMtekm 874
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASS---- 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  875 vqlneekfslgVEIKTLKEQLnllsrteeatkeqveesgagsslklghdesgqEGLQQELELLRKESEQRKRKLQAALIN 954
Cdd:COG4913    685 -----------DDLAALEEQL--------------------------------EELEAELEELEEELDELKGEIGRLEKE 721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  955 RKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWgtskWREVEASLKQTISEKEVELEGIRRDLK 1034
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREN----LEERIDALRARLNRAEEELERAMRAFN 797


                   ..
gi 1039751024 1035 EK 1036
Cdd:COG4913    798 RE 799
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1912-2295 1.54e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1912 VSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 1991
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1992 LEfvhtesqkdldvtkgnlaqAVEHRKKAQAELSSFKILLDDTQSEAARVladnlklkKELQSNKESIKSQIKQKDEDLL 2071
Cdd:COG4717    128 LP-------------------LYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2072 RRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDS---------------------- 2129
Cdd:COG4717    181 ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAaaleerlkearlllliaaalla 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2130 -------------------------TLAQLAAFTKSMSSLQDDRDRVIDEA----------KKWERRFGDAIQTKEEEVR 2174
Cdd:COG4717    261 llglggsllsliltiagvlflvlglLALLFLLLAREKASLGKEAEELQALPaleeleeeelEELLAALGLPPDLSPEELL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2175 LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTE-----LQHHQKAYDKLQEENKELTSQLEDARQLYHD 2249
Cdd:COG4717    341 ELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEeelraALEQAEEYQELKEELEELEEQLEELLGELEE 420

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751024 2250 SKNELTK--LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAD 2295
Cdd:COG4717    421 LLEALDEeeLEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2671-2842 1.67e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2671 AQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTS 2750
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2751 KDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEV-------QSLKKAMS 2823
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRE 769

                          170
                   ....*....|....*....
gi 1039751024 2824 SLQNDRDRLLKELKNLQQQ 2842
Cdd:COG4913    770 NLEERIDALRARLNRAEEE 788
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2493-2931 1.81e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2493 IKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2572
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2573 Q---LKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELA 2649
Cdd:COG4717    147 RleeLEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2650 RDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQL-------KEWQDSSREGD 2722
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALlflllarEKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2723 VLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQneRDRLWSELEKFRKSEEGKQR 2802
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVEDE 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2803 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLqqqylqmsQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL 2882
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEEL--------LEALDEEELEEELEELEEELEELEEELEELREELA 456

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2883 SWQHELRQLRMEKNSWEL-HERRMKEQFLMAISDKDQQLGHLQSLLRELR 2931
Cdd:COG4717    457 ELEAELEQLEEDGELAELlQELEELKAELRELAEEWAALKLALELLEEAR 506
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1276-2034 2.00e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1276 IASELAKKSEEVLLLQDQINEQGLEI----QNLKAASVEAQAHTE----LLKQELESSQLKVAGLEH-LKTLQPELDALH 1346
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLeeieQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERsIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1347 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAK 1426
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1427 QQLQRklqaalisrkealkENKSLQEQLSSARDAVERLTKSLADVEsqvsvqnqekdavlGKLTILQEERDKLIAEMDRF 1506
Cdd:TIGR02169  402 NELKR--------------ELDRLQEELQRLSEELADLNAAIAGIE--------------AKINELEEEKEDKALEIKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1507 LLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVES 1586
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR-------ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1587 VRQ--EKQELYAKLRSTESDKRerekqLQDAEQEMEEMKEKMRKFAKSKQ---------QKILELEEENDRLR------- 1648
Cdd:TIGR02169  527 VAQlgSVGERYATAIEVAAGNR-----LNNVVVEDDAVAKEAIELLKRRKagratflplNKMRDERRDLSILSedgvigf 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1649 -------------AEAQPVGGTG--ESMEA---------LLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETR 1704
Cdd:TIGR02169  602 avdlvefdpkyepAFKYVFGDTLvvEDIEAarrlmgkyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1705 NL-KLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSD-----SAKLEDSEAILMgdgakpgvsetfSS 1778
Cdd:TIGR02169  682 RLeGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQeeeklKERLEELEEDLS------------SL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1779 HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKL 1858
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1859 KETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1938
Cdd:TIGR02169  828 KEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1939 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLE-------------RISALEKTVKALEFVHTESQKDLDV 2005
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEE 983

                          810       820
                   ....*....|....*....|....*....
gi 1039751024 2006 TKGNLAQAVEHRKKAQAELSSFKILLDDT 2034
Cdd:TIGR02169  984 VLKRLDELKEKRAKLEEERKAILERIEEY 1012
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1006-1258 2.05e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1006 SKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDA 1085
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1086 GNGGSAAPVKETAASSppgagGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAy 1165
Cdd:COG3883     99 GGSVSYLDVLLGSESF-----SDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1166 hhLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAA 1245
Cdd:COG3883    173 --LEAQQAEQEALLAQLSAEEAAAE-AQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249

                          250
                   ....*....|...
gi 1039751024 1246 LQATVSVAQIQAQ 1258
Cdd:COG3883    250 GAAGAAGAAAGSA 262
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 643-996 2.05e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.07  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  643 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLtQLSEEVKESAEEARstLAAVTEE------RDQLLYQVkel 716
Cdd:PLN03229   435 EGEVEKLKEQILKAKESSSKPSELALNEMIEKLKKEIDL-EYTEAVIAMGLQER--LENLREEfskansQDQLMHPV--- 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  717 dvLAELRARV-QELESSLAEAEkqrglDYESQRAQHNLLTEqiHSLSIEAKSKDVKIEALQRELDgvqlQFCEQGTQMKT 795
Cdd:PLN03229   509 --LMEKIEKLkDEFNKRLSRAP-----NYLSLKYKLDMLNE--FSRAKALSEKKSKAEKLKAEIN----KKFKEVMDRPE 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  796 LQSQLEA-KEREVREGTERLRDISQEM-EGLSQALSQKELEIAK----MD-QLLLEKQKDVETLQQTIQEkdqqvtelsf 868
Cdd:PLN03229   576 IKEKMEAlKAEVASSGASSGDELDDDLkEKVEKMKKEIELELAGvlksMGlEVIGVTKKNKDTAEQTPPP---------- 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  869 SMTEKMVQLNEEkfsLGVEIKTLKEQLNLLSRTEEatkeqveesgagssLKLGHDESGQEGLQQELELLRKESEQRKRKL 948
Cdd:PLN03229   646 NLQEKIESLNEE---INKKIERVIRSSDLKSKIEL--------------LKLEVAKASKTPDVTEKEKIEALEQQIKQKI 708

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751024  949 QAALiNRKELLQKVSQLEEELAKVREDSRkeipfGENERRKLEEDREN 996
Cdd:PLN03229   709 AEAL-NSSELKEKFEELEAELAAARETAA-----ESNGSLKNDDDKEE 750
PTZ00121 PTZ00121
MAEBL; Provisional
 2032-2755 2.07e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2032 DDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLlRRLEQ---AEEKHRKEKKNMQEklDALHREKAHVEETLAE 2108
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDA-RKAEEarkAEDARKAEEARKAE--DAKRVEIARKAEDARK 1165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2109 IQVSltRKDQEMKELQGsldstlAQLAAFTKSMSSLQDDRD-RVIDEAKKWERrfgdaIQTKEEEVRLKEENCIALKDQL 2187
Cdd:PTZ00121  1166 AEEA--RKAEDAKKAEA------ARKAEEVRKAEELRKAEDaRKAEAARKAEE-----ERKAEEARKAEDAKKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2188 RQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENK-ELTSQLEDARQLYHDSKNELTKLESELKSLKD 2266
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2267 QTTDLNNSLEKCKEHENNLEGIIKQQEadiqnckfscEQLETDLAASRELTSRlHDEINAKEQKIISLLSGKEEAIQLAv 2346
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAE----------EAKKAAEAAKAEAEAA-ADEAEAAEEKAEAAEKKKEEAKKKA- 1380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2347 eELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKtnqltEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRivsd 2426
Cdd:PTZ00121  1381 -DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK-----KKADEAKKKAEEKKKADEAKKKAEEAKKADEAK---- 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2427 yRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRglrshmddlNSENAKLDAELVQYRRDlneVIAIKDSQQKQLLDAQL 2506
Cdd:PTZ00121  1451 -KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK---------KADEAKKKAEEAKKKAD---EAKKAAEAKKKADEAKK 1517

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2507 QQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQL-----KAKEEEL 2581
Cdd:PTZ00121  1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2582 QRLNMALSSSQKRTADLEEElVCVQKEATRKVSEIE---DQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQK 2658
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEE-AKIKAEELKKAEEEKkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2659 LLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVL 2738
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756

                          730
                   ....*....|....*..
gi 1039751024 2739 SRLEKLNQQLTSKDEQL 2755
Cdd:PTZ00121  1757 KKIAHLKKEEEKKAEEI 1773
PTZ00121 PTZ00121
MAEBL; Provisional
 1277-1736 2.09e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1277 ASELAKKSEEVLLLQDQINEQGLEIqnlKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1356
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEA---KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1357 NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA 1436
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1437 LISRK-EALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERdkliaemdrfllenqslsg 1515
Cdd:PTZ00121  1474 EAKKKaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK------------------- 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1516 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELY 1595
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAE-----EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1596 AKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEAllssNSSLKEEL 1675
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA----EEAKKAEE 1685

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 1676 EKITLEHKTLSKEFEALMAE---KDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEV 1736
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEelkKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA 1749
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2154-2825 2.10e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2154 EAKKWERRFGdaiQTKEEEVRLKEENcIALKDQLRQMAIHMEELKITVSRLEH-----DKEIWESKAqtELQHHQKAYDK 2228
Cdd:pfam12128  242 EFTKLQQEFN---TLESAELRLSHLH-FGYKSDETLIASRQEERQETSAELNQllrtlDDQWKEKRD--ELNGELSAADA 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2229 LQEENKELTSQLEDARQLYHDSKNELTKLESE-LKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADI-QNCKFSCEQL 2306
Cdd:pfam12128  316 AVAKDRSELEALEDQHGAFLDADIETAAADQEqLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIkEQNNRDIAGI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2307 ETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVAleeenkraLEKTN 2386
Cdd:pfam12128  396 KDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEL--------LLQLE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2387 QLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEmrgLRSHM 2466
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF---LRKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2467 DDLNSENAKLDAELVQYRRDLN-EVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQ 2541
Cdd:pfam12128  545 PDWEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLygvkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2542 KEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKVSEIEDQlK 2621
Cdd:pfam12128  625 EQLVQANGELEKASREETFAR---------TALKNARLDLRRLFDEKQSEKDK---KNKALAERKDSANERLNSLEAQ-L 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2622 KELKHLHHDAgimrnetetAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAfgrsmsSLQDSRDHATEELGDLKKKY 2701
Cdd:pfam12128  692 KQLDKKHQAW---------LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA------AIAARRSGAKAELKALETWY 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2702 DASLKELAQlkewqdssrEGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLH-LSSELESSHNQVQSISKAMTSLQ 2780
Cdd:pfam12128  757 KRDLASLGV---------DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQEtWLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1039751024 2781 NERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL 2825
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKL 872
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1795-2390 2.11e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1795 RIAELEMEKQKDRELSQALENEKNALLTQISakdsELKLLEEevTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEER-- 1872
Cdd:pfam05483  170 KTKKYEYEREETRQVYMDLNNNIEKMILAFE----ELRVQAE--NARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQvs 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1873 -LMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVeseirKEYMEKIQGAQKGPANK 1951
Cdd:pfam05483  244 lLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI-----KMSLQRSMSTQKALEED 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1952 SH--AKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKI 2029
Cdd:pfam05483  319 LQiaTKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2030 LLDDTQ---SEAARVLADNLKLKKElQSNKESIKSQIKQKDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHVEETL 2106
Cdd:pfam05483  399 FKNNKEvelEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIFLLQARE----KEIHDLEIQLTAIKTSEEHYLKEV 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2107 AEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS----SLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE---- 2178
Cdd:pfam05483  474 EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesv 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2179 ------NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2249
Cdd:pfam05483  554 reefiqKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCnnlKKQIENKNKNIEELHQENKALKKKGSAENKQLNA 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2250 SKNELTKLESELKSLKDQTTDLNNSLEKCKE----HENNLEGIIKQQEADI-------QNCKFSCEQLETDLAASRELTS 2318
Cdd:pfam05483  634 YEIKVNKLELELASAKQKFEEIIDNYQKEIEdkkiSEEKLLEEVEKAKAIAdeavklqKEIDKRCQHKIAEMVALMEKHK 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2319 RLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE 2390
Cdd:pfam05483  714 HQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2230-2452 2.11e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2230 QEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETD 2309
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2310 LAASRELTSRLHDEI-NAKEQKIISLLSGKEEAIQLA-----VEELHQQHSKEIKELENLLSQEEEENVALEEENKRALE 2383
Cdd:COG4942     99 LEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751024 2384 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAEN 2452
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 201-418 2.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  201 LISTLQTQLSQTQAEQAAQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLK---NTM 277
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  278 ETERQESKTLMEKVELEVAER---------------KLSFHNLQEEMHQLQ--GQLERAGQAQADLETQYSALQQRHKTE 340
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELlralyrlgrqpplalLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751024  341 MEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQ 418
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
193-403 2.58e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 2.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  193 QQLQEKEELISTLQTQLSQTQAEQAAQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRnqvlsqqlqlleaehnt 272
Cdd:COG4913    262 ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREE----------------- 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  273 lKNTMETERQESKTlmEKVElevaerklsfhNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEktacilsLQ 352
Cdd:COG4913    325 -LDELEAQIRGNGG--DRLE-----------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEE-------FA 383

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751024  353 KNEQELQSACAALKEEnsklLQEKHDQAAESAQAMRQLEDQLQQKSKEISQ 403
Cdd:COG4913    384 ALRAEAAALLEALEEE----LEALEEALAEAEAALRDLRRELRELEAEIAS 430
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 2518-2617 2.61e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2518 KLEERLKGLEAEKQSLQMSSDALQKEK-QGLSKEIKNLQTQLTAL----QEEGTLgvyHAQLKAKEEELQRLNMALSSSQ 2592
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEALkarwEAEKEL---IEEIQELKEELEQRYGKIPELE 491

                           90       100
                   ....*....|....*....|....*
gi 1039751024 2593 KRTADLEEELVCVQKEATRKVSEIE 2617
Cdd:COG0542    492 KELAELEEELAELAPLLREEVTEED 516
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1380-1968 2.81e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1380 QERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkpTELEEETNAKQqlqRKLQAALISRKEALKENKSLQEQLSSARD 1459
Cdd:pfam05483  200 EELRVQAENARLEMHFKLKEDHEKIQHLE--------EEYKKEINDKE---KQVSLLLIQITEKENKMKDLTFLLEESRD 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1460 AVERLtksladvESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELE 1539
Cdd:pfam05483  269 KANQL-------EEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1540 SVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQL---QDAE 1616
Cdd:pfam05483  342 KAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILaedEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1617 QEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEK 1696
Cdd:pfam05483  422 DEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1697 DALSEETRNLKLQVEAQvlkqasleateksdePKDVIEevtqavvGKSQERDALSDSAKLEDSEAILMgDGAKPGVSETF 1776
Cdd:pfam05483  502 KELTQEASDMTLELKKH---------------QEDIIN-------CKKQEERMLKQIENLEEKEMNLR-DELESVREEFI 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1777 SSHDDIKNylqQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEE----VTKRTTLNQQIQEEL 1852
Cdd:pfam05483  559 QKGDEVKC---KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkalKKKGSAENKQLNAYE 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1853 CRVTKLKETAEEEKDDLEErlmnqlaelngSIGNYYQDVTDAQIKNEQLESEMrnlqrcvseleEEKQQLVKEKTKVESE 1932
Cdd:pfam05483  636 IKVNKLELELASAKQKFEE-----------IIDNYQKEIEDKKISEEKLLEEV-----------EKAKAIADEAVKLQKE 693

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1039751024 1933 IRKEYMEKIqgAQKGPANKSHAKELQELLREKQQEV 1968
Cdd:pfam05483  694 IDKRCQHKI--AEMVALMEKHKHQYDKIIEERDSEL 727
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2510-2995 2.89e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2510 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2588
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2589 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2668
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2669 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2748
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2749 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2820
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2821 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2892
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2893 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 2961
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1039751024 2962 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 2995
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1958-2174 2.93e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1958 QELLREKQQEVKQLQKdciryleRISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSE 2037
Cdd:COG4942     19 ADAAAEAEAELEQLQQ-------EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2038 AARVLADNLKLKKELqsnKESIKSQIKQKDEDLLRRLEQAEEKHRKEKknMQEKLDALHREKAHVEETLAEIQVSLTRKD 2117
Cdd:COG4942     92 IAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVR--RLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751024 2118 QEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2174
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2169-2713 3.23e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 3.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2169 KEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQhhqkaydkLQEENKELTSQLEDARQLYH 2248
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETE--------LCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2249 DSkneLTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ-------NCKFSCEQLETDLAASRELTSRLH 2321
Cdd:pfam01576   75 EI---LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQklqlekvTTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2322 DEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES 2399
Cdd:pfam01576  152 KERKLLEERISEFTSnlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQI 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2400 FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAE----------NNKLKEEMRGLRSHMDD- 2468
Cdd:pfam01576  232 AELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESEraarnkaekqRRDLGEELEALKTELEDt 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2469 LNSENA------KLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKElrnectkLEERLKGLEAEKQSLQMSSDALQK 2542
Cdd:pfam01576  312 LDTTAAqqelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE-------LTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2543 EKQGLSKEIKNLQTqltalqeeGTLGVYHAQLKAkEEELQRLNMALSSSQKRTADLEEELVCVQKEaTRKVSEIEDQLKK 2622
Cdd:pfam01576  385 ENAELQAELRTLQQ--------AKQDSEHKRKKL-EGQLQELQARLSESERQRAELAEKLSKLQSE-LESVSSLLNEAEG 454

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2623 ELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYD 2702
Cdd:pfam01576  455 KNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534

                          570
                   ....*....|.
gi 1039751024 2703 ASLKELAQLKE 2713
Cdd:pfam01576  535 EDAGTLEALEE 545
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2150-2881 3.47e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2150 RVIDEAKKWERRFGDAIQTKEEEVRLKE---ENCIALKDQLRQMAIHMEELKITVSRLEHD--------KEIWESKAQT- 2217
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKqykEKACEIRDQITSKEAQLESSREIVKSYENEldplknrlKEIEHNLSKIm 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2218 ELQHHQKAYDKLQEENKELTSQLEDAR-QLYHDSKNELTKLE----SELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQ 2292
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEKDNSELELKMeKVFQGTDEQLNDLYhnhqRTVREKERELVDCQRELEK-----LNKERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2293 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQL--AVEELHQQHSKEIKELENLLSQEEEE 2370
Cdd:TIGR00606  341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIknFHTLVIERQEDEAKTAAQLCADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2371 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQL--EERHLSaILEKDQLIQDA 2448
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2449 AAENNKLKEEMRGLRSHMDDLNSENAKLDAE---------LVQYRRDLNEVIAIKDSQQKQLLDAQL---QQNKELRNEC 2516
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2517 TKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALqEEGTLGVYHAQlkAKEEELQRLNMALSSSQKRTA 2596
Cdd:TIGR00606  580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY-EDKLFDVCGSQ--DEESDLERLKEEIEKSSKQRA 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2597 DLEEElvcvqkeatrkvSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAF 2676
Cdd:TIGR00606  657 MLAGA------------TAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2677 GRSMSSLQDSR----DHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSR---LEKLNQQLT 2749
Cdd:TIGR00606  725 RDEMLGLAPGRqsiiDLKEKEIPELRNKLQKVNRDIQRLK--NDIEEQETLLGTIMPEEESAKVCLTDvtiMERFQMELK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2750 SKDEQLLHLSSELESS--HNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaEVQSLKKAMSSLQN 2827
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE-----------QIQHLKSKTNELKS 871

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751024 2828 DRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQEN 2881
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEK 925
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 844-1095 3.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  844 EKQKDVETLQQTIQEKDQQVTelsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHD 923
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELA-----------ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA----ELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  924 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDREnrddpeew 1003
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-------- 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1004 gtsKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTM 1083
Cdd:COG4942    161 ---ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237

                          250
                   ....*....|..
gi 1039751024 1084 DAGNGGSAAPVK 1095
Cdd:COG4942    238 AAAERTPAAGFA 249
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2010-2648 3.59e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2010 LAQAVEH---RKKAQAELSSFKILLDDTQSEAARVLADNLK-----LKKELQSNKESIkSQIKQKDEDLLRRLEQAEEKH 2081
Cdd:COG4913    254 LEPIRELaerYAAARERLAELEYLRAALRLWFAQRRLELLEaeleeLRAELARLEAEL-ERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2082 R----KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKK 2157
Cdd:COG4913    333 RgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEA 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2158 WERRFGDAIQTKEEEVR-LKE------ENCIALKDQLRqmaihmEELKITVSRL---------EHDKEIWESKAQTELqh 2221
Cdd:COG4913    413 ALRDLRRELRELEAEIAsLERrksnipARLLALRDALA------EALGLDEAELpfvgelievRPEEERWRGAIERVL-- 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2222 HQKAYDKLQEENkeltsQLEDARQLYHDSKNELT----KLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2297
Cdd:COG4913    485 GGFALTLLVPPE-----HYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRF 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2298 N--CKFSCEQLE-TDLAASRE-LTSRLHD--EINAKEQKIISLLSGKEEAIQLAVEElhqqhsKEIKELEnllsqeeeen 2371
Cdd:COG4913    560 DyvCVDSPEELRrHPRAITRAgQVKGNGTrhEKDDRRRIRSRYVLGFDNRAKLAALE------AELAELE---------- 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2372 valeeenkRALEKTNQLTEALEAIKKESFEQKAQLdSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAE 2451
Cdd:COG4913    624 --------EELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDVASAEREIAELEAE-LERLDASSDDLAALEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2452 NNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdsqQKQLLDAQLQQNKELRnecTKLEERLKGLEAEKQ 2531
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL-------QDRLEAAEDLARLELR---ALLEERFAAALGDAV 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2532 SLQMsSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEElvcvqkEATR 2611
Cdd:COG4913    764 EREL-RENLEERIDALRARLNRAEEELERAMRA-----FNREWPAETADLDADLESLPEYLALLDRLEED------GLPE 831

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 1039751024 2612 KVSEIEDQLKK----ELKHLHHDagiMRNETETAEERVAEL 2648
Cdd:COG4913    832 YEERFKELLNEnsieFVADLLSK---LRRAIREIKERIDPL 869
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 65-479 3.91e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   65 VELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIKTQgGAALPPEAQaEELSKHNKSstee 144
Cdd:TIGR04523  242 NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELE-QNNKKIKELEKQLNQLKSE-ISDLNNQKE-QDWNKELKS---- 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  145 emeiekikhELQEKEKLISSLQAQLDQSEQA-SQLDKSSAEmedfvlMKQQLQEKEELISTLQTQLSQTQaeqaaQKLRV 223
Cdd:TIGR04523  315 ---------ELKNQEKKLEEIQNQISQNNKIiSQLNEQISQ------LKKELTNSESENSEKQRELEEKQ-----NEIEK 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  224 MQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTME---TERQESKTLMEKVELEVAERKL 300
Cdd:TIGR04523  375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIErlkETIIKNNSEIKDLTNQDSVKEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  301 SFHNLQEEMHQLQGQLEragqaqaDLETQYSALQQ---RHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKH 377
Cdd:TIGR04523  455 IIKNLDNTRESLETQLK-------VLSRSINKIKQnleQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIE 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  378 DQAAESAQAMRQLeDQLQQKSKEISQFVNKPNL-----QKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENE-- 450
Cdd:TIGR04523  528 KLESEKKEKESKI-SDLEDELNKDDFELKKENLekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEie 606

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1039751024  451 -KGALLLS-SGELEELKAENEKLSSRITLLE 479
Cdd:TIGR04523  607 eKEKKISSlEKELEKAKKENEKLSSIIKNIK 637
PLN02939 PLN02939
transferase, transferring glycosyl groups
 27-255 4.39e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.97  E-value: 4.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   27 ASSDADSSQETAMESNNRIMESTQEDALHRLAEAEKLVVELkdiiSQKDVQLQQKDEALQEEKKAAENKIK--------- 97
Cdd:PLN02939   107 AIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLL----NQARLQALEDLEKILTEKEALQGKINilemrlset 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   98 --KIKLHAKAKI----------MSLNKHMEEIKTQGGAALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSL 165
Cdd:PLN02939   183 daRIKLAAQEKIhveileeqleKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKL 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  166 QAQ---LDQS--EQASQLDKSSAEMEDFVLMKQQ-LQEKEElisTLQTQLSQT--QAEQAA------QKLRVMQRKLEEH 231
Cdd:PLN02939   263 EKErslLDASlrELESKFIVAQEDVSKLSPLQYDcWWEKVE---NLQDLLDRAtnQVEKAAlvldqnQDLRDKVDKLEAS 339

                          250       260
                   ....*....|....*....|....*..
gi 1039751024  232 -EEALLGR--AQVVDLLQKELTSAEQR 255
Cdd:PLN02939   340 lKEANVSKfsSYKVELLQQKLKLLEER 366
46 PHA02562
endonuclease subunit; Provisional
 2403-2628 4.40e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.69  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2403 KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQ 2482
Cdd:PHA02562   194 QQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQ 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2483 YRRDlneviaIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEaekQSLQMSSDALQKEKQ------GLSKEIKNLQT 2556
Cdd:PHA02562   274 FQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQ---HSLEKLDTAIDELEEimdefnEQSKKLLELKN 344

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751024 2557 QLTalQEEGTLGVYHAQLKAKEEELQRLnmalsssQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLH 2628
Cdd:PHA02562   345 KIS--TNKQSLITLVDKAKKVKAAIEEL-------QAEFVDNAEELAKLQDELDKIVKTKSE-LVKEKYHRG 406
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2488-2720 4.48e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2488 NEVIAIKDSQQKQLLDAQLQQNKELRnectKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtL 2567
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--I 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2568 GVYHAQLKAKEEELQRLnmaLSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERVAE 2647
Cdd:COG4942     93 AELRAELEAQKEELAEL---LRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751024 2648 LARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRE 2720
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1961-2174 4.61e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1961 LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAAR 2040
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2041 VLADNLKLKKELQS-------NKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2113
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 2114 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2174
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
PRK12704 PRK12704
phosphodiesterase; Provisional
 2016-2178 4.93e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 4.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2016 HRKKAQAELSSFKILLDDTQsEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRR--LEQAEEKHRKEKKNMQEKLD 2093
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2094 ALHREKAHVEETLAEI---QVSLTRKDQEMKELQGSLDSTLAQLAAFTKsmsslQDDRDRVIDEAKKwERRFGDAIQTKE 2170
Cdd:PRK12704   104 LLEKREEELEKKEKELeqkQQELEKKEEELEELIEEQLQELERISGLTA-----EEAKEILLEKVEE-EARHEAAVLIKE 177


                   ....*...
gi 1039751024 2171 EEVRLKEE 2178
Cdd:PRK12704   178 IEEEAKEE 185
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2502-2933 5.05e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 5.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2502 LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE-----------EGTLGVY 2570
Cdd:PRK03918   226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEY 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2571 HAQLKAKEEELQRLNMALSSSQKRTADLE------EELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEER 2644
Cdd:PRK03918   306 LDELREIEKRLSRLEEEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2645 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDS---------------RDHATEELGDLKKKYDASLKELA 2709
Cdd:PRK03918   386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2710 -QLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSE-LESSHNQVQSISKAMTSLQNERDRLW 2787
Cdd:PRK03918   466 kELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2788 SELEKFrKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL----QNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQES 2863
Cdd:PRK03918   546 KELEKL-EELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 2864 QDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHE-RRMKEQFLMAISDKDQQLGHLQSLLRELRSS 2933
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElREEYLELSRELAGLRAELEELEKRREEIKKT 695
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 819-1042 5.16e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 5.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  819 QEMEGLSQALSQKELEIAKMDQLLLE--KQKDVETLQQTIQEKDQQVTElSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 896
Cdd:pfam17380  348 RELERIRQEERKRELERIRQEEIAMEisRMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQRKIQQQKVEMEQIR 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  897 llSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDS 976
Cdd:pfam17380  427 --AEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEER 504

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024  977 RKEIPFGENERRKLEEDRENRDdpeewgTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEE 1042
Cdd:pfam17380  505 KQAMIEEERKRKLLEKEMEERQ------KAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 72-332 5.19e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   72 SQKDVQLQQKDEALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKtqggaalppeAQAEELSKHNKssteeemeieki 151
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIA----------ALARRIRALEQ------------ 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  152 khELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDFVlmkqQLQEKEELISTLQTQLSQTQAEQAAQKLRVMQRKLEEH 231
Cdd:COG4942     77 --ELAALEAELAELEKEIAELRA--ELEAQKEELAELL----RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPAR 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  232 EEallgRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQ 311
Cdd:COG4942    149 RE----QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224

                          250       260
                   ....*....|....*....|.
gi 1039751024  312 LQGQLERAGQAQADLETQYSA 332
Cdd:COG4942    225 LEALIARLEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 719-951 5.71e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  719 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQlqfceqgTQMKTLQS 798
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEE----KALLKQLAALERRIAALARRIRALEQELAALEAELAELE-------KEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  799 QLEAKEREVRE---GTERLRDISQEMEGLSQA-LSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKM 874
Cdd:COG4942     98 ELEAQKEELAEllrALYRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  875 VQLNE---EKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAA 951
Cdd:COG4942    178 ALLAEleeERAALEALKAERQKLLARLEKELAELAAELAEL-----------QQEAEELEALIARLEAEAAAAAERTPAA 246
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1391-1581 6.17e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1391 LEMQAKEHEERLKQAQVEICELKKK------PTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERL 1464
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKnglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1465 TKS--LADVESQVSVQNQEKDAVLGKLT-------ILQEERDKLIAEMdrflleNQSLSGSCESLKLALGGLTEDKEKLM 1535
Cdd:COG3206    260 LQSpvIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQL------QQEAQRILASLEAELEALQAREASLQ 333

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751024 1536 EELESVRSsKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1581
Cdd:COG3206    334 AQLAQLEA-RLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
46 PHA02562
endonuclease subunit; Provisional
 1783-1973 6.73e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 6.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1783 KNYLQQLDQLKG-RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1861
Cdd:PHA02562   201 NKNIEEQRKKNGeNIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKM 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1862 AEE------------EKDDLEERLMNQLAELNGSignyYQDVTDAQIKNEQLESEMRNLQRCVSEL----EEEKQQL--- 1922
Cdd:PHA02562   281 YEKggvcptctqqisEGPDRITKIKDKLKELQHS----LEKLDTAIDELEEIMDEFNEQSKKLLELknkiSTNKQSLitl 356

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751024 1923 VKEKTKVESEIRKeymekiqgAQKGPANksHAKELQELLREKQQEVKQLQK 1973
Cdd:PHA02562   357 VDKAKKVKAAIEE--------LQAEFVD--NAEELAKLQDELDKIVKTKSE 397
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1302-1484 7.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 7.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1302 QNLKAASVEAQAHTELLKQELESSQLKVAGLEH-LKTLQPELDALhkhmgQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQ 1380
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAaLEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1381 ERLIKALHTQLEMQA------------KEHEERLKQAQVEICELKKKPTE--------LEEETNAKQQLQRKLQAALISR 1440
Cdd:COG3206    239 EARLAALRAQLGSGPdalpellqspviQQLRAQLAELEAELAELSARYTPnhpdvialRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1039751024 1441 KEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDA 1484
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEV 362
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2538-2795 7.33e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 7.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2538 DALQKEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIE 2617
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALK---------KEEKALLKQLAALERRIAALARRIRALEQEL----AALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2618 DQLKKelkhlhhdagiMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDL 2697
Cdd:COG4942     90 KEIAE-----------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2698 KKKYDASLKELAQLKEWQDSSREgdvlsqaafplstseNVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMT 2777
Cdd:COG4942    159 LAELAALRAELEAERAELEALLA---------------ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                          250
                   ....*....|....*...
gi 1039751024 2778 SLQNERDRLWSELEKFRK 2795
Cdd:COG4942    224 ELEALIARLEAEAAAAAE 241
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 645-838 7.36e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  645 ELERLKTQVLELETSLHTAEETYkRNLSEKVKEISS-LTQLSEEVKESAEEARSTLAAVTEERdqllyqvkelDVLAELR 723
Cdd:pfam19220   42 ELPQAKSRLLELEALLAQERAAY-GKLRRELAGLTRrLSAAEGELEELVARLAKLEAALREAE----------AAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  724 ARVQELESSLAEAEKQrgLDYESQRAQHnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 803
Cdd:pfam19220  111 IELRDKTAQAEALERQ--LAAETEQNRA--LEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQ 186

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1039751024  804 EREVREGTERLRDISQEMEGLSQALSQKELEIAKM 838
Cdd:pfam19220  187 AAELAELTRRLAELETQLDATRARLRALEGQLAAE 221
mukB PRK04863
chromosome partition protein MukB;
2304-2651 7.78e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 7.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2304 EQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAI--QLAV------EELHQQHSKEIKELENLLSQEEeenvale 2375
Cdd:PRK04863   785 EKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIgsHLAVafeadpEAELRQLNRRRVELERALADHE------- 857

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2376 eenkralEKTNQLTEALEAIKkesfEQKAQLDSFVKSMSSLQDDR--DRIvsdyRQLEERhLSAILEKDQLIQDAAAENN 2453
Cdd:PRK04863   858 -------SQEQQQRSQLEQAK----EGLSALNRLLPRLNLLADETlaDRV----EEIREQ-LDEAEEAKRFVQQHGNALA 921

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2454 KLKEEMRGLRS---HMDDLNSENAKLDAELVQYR---RDLNEVIAIK------DSQQKQLLDAQL-----QQNKELRNEC 2516
Cdd:PRK04863   922 QLEPIVSVLQSdpeQFEQLKQDYQQAQQTQRDAKqqaFALTEVVQRRahfsyeDAAEMLAKNSDLneklrQRLEQAEQER 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2517 TKLEERLKGLEAE-------KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaQLKAKEEElqrLNMALS 2589
Cdd:PRK04863  1002 TRAREQLRQAQAQlaqynqvLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEE--------RARARRDE---LHARLS 1070

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024 2590 SSQKRTADLEEELVCVQKEAtrkvseieDQLKKELKHLHHDAGIMRNETETAEER---VAELARD 2651
Cdd:PRK04863  1071 ANRSRRNQLEKQLTFCEAEM--------DNLTKKLRKLERDYHEMREQVVNAKAGwcaVLRLVKD 1127
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
156-336 7.82e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 7.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  156 QEKEKLISSLQAQLDQSEQasQLDKSSAEMEDF------VLMKQQLQEKEELISTLQTQLSQTQAE--QAAQKLRVMQRK 227
Cdd:COG3206    171 EEARKALEFLEEQLPELRK--ELEEAEAALEEFrqknglVDLSEEAKLLLQQLSELESQLAEARAElaEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  228 LEEHEEAL--LGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETER----QESKTLMEKVELEVAERKLS 301
Cdd:COG3206    249 LGSGPDALpeLLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRaqlqQEAQRILASLEAELEALQAR 328

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1039751024  302 FHNLQEEMHQLQGQLERAGQAQADL----------ETQYSALQQR 336
Cdd:COG3206    329 EASLQAQLAQLEARLAELPELEAELrrlerevevaRELYESLLQR 373
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1114-1590 8.02e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 8.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1114 ELEGRILDLEKDKTQLQK---KLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQ 1190
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1191 CQAREsidrqlpgtgqqepgppapsLEGISLEDTEPASESDLHAAQPSPPG-ETAALQATVSVAQIQAQLKEMEVEKEEL 1269
Cdd:TIGR04523  295 SEISD--------------------LNNQKEQDWNKELKSELKNQEKKLEEiQNQISQNNKIISQLNEQISQLKKELTNS 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1270 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQahTELLKQELESSQLKvaglEHLKTLQPELDALHKHM 1349
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE--SKIQNQEKLNQQKD----EQIKKLQQEKELLEKEI 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1350 GQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQL 1429
Cdd:TIGR04523  429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1430 QrklqaalisrkealKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT--ILQEERDKLIAEMDRFL 1507
Cdd:TIGR04523  509 E--------------EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDEKNKEIEELK 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1508 LENQSLSGSCESLKLALGGLTEDKEKLMEELEsvrsSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESV 1587
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE----EKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQI 650


                   ...
gi 1039751024 1588 RQE 1590
Cdd:TIGR04523  651 KET 653
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 50-401 8.24e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 8.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   50 QEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIktqggaalppEA 129
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL----------EE 741

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  130 QAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQA---SQLDKSSAEMEDfvlMKQQLQEKEELISTLQ 206
Cdd:TIGR02169  742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshSRIPEIQAELSK---LEEEVSRIEARLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  207 TQLS--QTQAEQAAQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNtmetERQES 284
Cdd:TIGR02169  819 QKLNrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK----ERDEL 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  285 KTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLEtqysalqqRHKTEMEEKTACILSL---QKNEQELQSA 361
Cdd:TIGR02169  895 EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE--------DPKGEDEEIPEEELSLedvQAELQRVEEE 966

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751024  362 CAALKEENSKL-------------LQEKHDQAAESAQAMRQLEDQLQQKSKEI 401
Cdd:TIGR02169  967 IRALEPVNMLAiqeyeevlkrldeLKEKRAKLEEERKAILERIEEYEKKKREV 1019
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1772-2257 8.26e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1772 VSETFSSHDDIKNYLQQLDQLKGRI----AELEMEKQKDRElsQALENEKNALLTQISAKDSELKLLEEEVTK-RTTLNQ 1846
Cdd:COG4913    257 IRELAERYAAARERLAELEYLRAALrlwfAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDElEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1847 QIQEELCRVTKLKETAEEEKDDLEERLmNQLAELNGSIGnyYQDVTDAqiknEQLESEMRNLQRCVSELEEEKQQLVKEK 1926
Cdd:COG4913    335 NGGDRLEQLEREIERLERELEERERRR-ARLEALLAALG--LPLPASA----EEFAALRAEAAALLEALEEELEALEEAL 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1927 TKVESEIRkeymekiqgaqkgpankshakELQELLREKQQEVKQLQ--KDCI-RYLERI-----SALEKTVKALEF---- 1994
Cdd:COG4913    408 AEAEAALR---------------------DLRRELRELEAEIASLErrKSNIpARLLALrdalaEALGLDEAELPFvgel 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 1995 --VHTESQK--------------DLDVTKGNLAQAVEH--RKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNK 2056
Cdd:COG4913    467 ieVRPEEERwrgaiervlggfalTLLVPPEHYAAALRWvnRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2057 --ESIKSQIKQK-------DEDLLRRLEQA--------EEKHRKEKK-------------NMQEKLDALHREKAHVEETL 2106
Cdd:COG4913    547 frAWLEAELGRRfdyvcvdSPEELRRHPRAitragqvkGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEEL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2107 AEIQVSLTRKDQEMKELQGSLDsTLAQLAAFT----------KSMSSLQDDRDRV------IDEAKKWERRFGDAIQTKE 2170
Cdd:COG4913    627 AEAEERLEALEAELDALQERRE-ALQRLAEYSwdeidvasaeREIAELEAELERLdassddLAALEEQLEELEAELEELE 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2171 EEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2250
Cdd:COG4913    706 EELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785


                   ....*..
gi 1039751024 2251 KNELTKL 2257
Cdd:COG4913    786 EEELERA 792
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2408-2866 8.86e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 8.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2408 SFVKSM--SSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAEN---NKLKEEMRGLRSHMDDLNSENAKLDAELVQ 2482
Cdd:COG4717     41 AFIRAMllERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2483 YRRDLNeviaikdsqqkqlLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQmssdALQKEKQGLSKEIKNLQTQLTALQ 2562
Cdd:COG4717    121 LEKLLQ-------------LLPLYQELEALEAELAELPERLEELEERLEELR----ELEEELEELEAELAELQEELEELL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2563 EEGTLgvyhaqlkAKEEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAE 2642
Cdd:COG4717    184 EQLSL--------ATEEELQDLAEELEELQQRLAELEEEL----EEAQEELEELEEELEQLENELEAAALEERLKEARLL 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2643 ERVAELARDLVEMEQKLLTVTKENKDLMAQIQA----FGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE--WQD 2716
Cdd:COG4717    252 LLIAAALLALLGLGGSLLSLILTIAGVLFLVLGllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAalGLP 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024 2717 SSREGDVLSQAAFPLSTSENVLSRLEKLNQQL------TSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSEL 2790
Cdd:COG4717    332 PDLSPEELLELLDRIEELQELLREAEELEEELqleeleQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQL 411

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024 2791 EKFRKSEEgkQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEmTELRPLKAQLQESQDQ 2866
Cdd:COG4717    412 EELLGELE--ELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAE 484
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
51-484 9.09e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 9.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   51 EDALHRLAEAEKLVVELKDIISQKDvQLQQKDEALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGaalppEAQ 130
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYA-ELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAE 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  131 AEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAE---MEDFVLMKQQLQEKEELISTLQT 207
Cdd:COG4717    141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELqdlAEELEELQQRLAELEEELEEAQE 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  208 QLSQTQAE----QAAQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHnTLKNTMETERQE 283
Cdd:COG4717    221 ELEELEEEleqlENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLA-LLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  284 SKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRH-KTEMEEKTACILSLQKNEQELQSAC 362
Cdd:COG4717    300 LGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLrEAEELEEELQLEELEQEIAALLAEA 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  363 AALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQtslpdvNNEGDQAVMEETVASLQK 442
Cdd:COG4717    380 GVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE------ELEEELEELEEELEELRE 453

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1039751024  443 RVVELENEKGALLlSSGELEELKAENEKLSSRITLLEAQNRA 484
Cdd:COG4717    454 ELAELEAELEQLE-EDGELAELLQELEELKAELRELAEEWAA 494
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 754-896 9.14e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 41.34  E-value: 9.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  754 LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE---GTERLRDISQEMEGLSQALSQ 830
Cdd:pfam15905  161 LMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEeksETEKLLEYITELSCVSEQVEK 240

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751024  831 KELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 896
Cdd:pfam15905  241 YKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLN 306
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
83-543 9.41e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 9.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024   83 EALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGAALPPEAQAEELSKhnkssteeemEIEKIKHELQEKEKLI 162
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEE----------ELEELEAELEELREEL 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  163 SSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQLSQTQAEQA---AQKLRVMQRKLEEHEEALLGRA 239
Cdd:COG4717    119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAelqEELEELLEQLSLATEEELQDLA 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  240 QVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERA 319
Cdd:COG4717    199 EELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  320 GQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSK 399
Cdd:COG4717    279 LFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  400 EISQFvnkpNLQKNETASQTSLPDVNnegdqAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLE 479
Cdd:COG4717    359 LEEEL----QLEELEQEIAALLAEAG-----VEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE 429

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751024  480 AQNRAGEADGTVCEVSTAGTTLLNRSDSSPEENGQAVLENTFSQKHKELSVLLVEMKEAQEEIA 543
Cdd:COG4717    430 LEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWA 493
PRK11281 PRK11281
mechanosensitive channel MscK;
157-334 9.67e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 9.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  157 EKEKLISSLQAQLdQSEQASqLDKSSAemedfvLMKQQLQEKEELISTLQTQLSQTQAEQAAQklrvmqrkleEHEEALL 236
Cdd:PRK11281   185 GGKALRPSQRVLL-QAEQAL-LNAQND------LQRKSLEGNTQLQDLLQKQRDYLTARIQRL----------EHQLQLL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  237 graQVVdLLQKELTSAEQRNQVLSQQLQLLEAEHNTL-KNTMETERQESKTLMEKVELEVAerkLSFHNLQeemhqLQGQ 315
Cdd:PRK11281   247 ---QEA-INSKRLTLSEKTVQEAQSQDEAARIQANPLvAQELEINLQLSQRLLKATEKLNT---LTQQNLR-----VKNW 314

                          170
                   ....*....|....*....
gi 1039751024  316 LERAGQAQADLETQYSALQ 334
Cdd:PRK11281   315 LDRLTQSERNIKEQISVLK 333
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 280-484 9.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  280 ERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQrhktEMEEKTACILSLQKNEQELQ 359
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQ----ELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751024  360 SACAALKEENSKLL-----------------QEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLP 422
Cdd:COG4942     97 AELEAQKEELAELLralyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751024  423 DV---NNEGDQAVMEETVASLQKRVVELENEKGALllsSGELEELKAENEKLSSRITLLEAQNRA 484
Cdd:COG4942    177 EAllaELEEERAALEALKAERQKLLARLEKELAEL---AAELAELQQEAEELEALIARLEAEAAA 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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