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Conserved domains on  [gi|1034640801|ref|XP_016863980|]
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UV-stimulated scaffold protein A isoform X1 [Homo sapiens]

Protein Classification

UV-stimulated scaffold protein A( domain architecture ID 10560856)

UV-stimulated scaffold protein A is a DUF2043 domain-containing protein that acts as a factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2043 pfam09740
Uncharacterized conserved protein (DUF2043); This is a 100 residue conserved region of a ...
 497-603 4.74e-59

Uncharacterized conserved protein (DUF2043); This is a 100 residue conserved region of a family of proteins found from fungi to humans. This region contains three conserved Cysteines and a motif of {CP}{y/l}{HG}.


:

Pssm-ID: 462871  Cd Length: 106  Bit Score: 194.35  E-value: 4.74e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034640801 497 ARAPVVPYGVDLHYWGQELpTAGKIVKSDSQ-HRFWKPSEVEEeVVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGR 575
Cdd:pfam09740   1 AKAPVVPFGLDLYYWGEEQ-EAGKVPKNNSGlHRFWGPSDVEE-VISAEKLAELNQRQITFAGKFEPVKHPCRAPLPNGG 78

                          90       100
                  ....*....|....*....|....*...
gi 1034640801 576 LCERQDRLKCPFHGKIVPRDDEGRPLDP 603
Cdd:pfam09740  79 LCPRRDRLKCPFHGKIIPRDDEGRPINP 106
 
Name Accession Description Interval E-value
DUF2043 pfam09740
Uncharacterized conserved protein (DUF2043); This is a 100 residue conserved region of a ...
 497-603 4.74e-59

Uncharacterized conserved protein (DUF2043); This is a 100 residue conserved region of a family of proteins found from fungi to humans. This region contains three conserved Cysteines and a motif of {CP}{y/l}{HG}.


Pssm-ID: 462871  Cd Length: 106  Bit Score: 194.35  E-value: 4.74e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034640801 497 ARAPVVPYGVDLHYWGQELpTAGKIVKSDSQ-HRFWKPSEVEEeVVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGR 575
Cdd:pfam09740   1 AKAPVVPFGLDLYYWGEEQ-EAGKVPKNNSGlHRFWGPSDVEE-VISAEKLAELNQRQITFAGKFEPVKHPCRAPLPNGG 78

                          90       100
                  ....*....|....*....|....*...
gi 1034640801 576 LCERQDRLKCPFHGKIVPRDDEGRPLDP 603
Cdd:pfam09740  79 LCPRRDRLKCPFHGKIIPRDDEGRPINP 106
 
Name Accession Description Interval E-value
DUF2043 pfam09740
Uncharacterized conserved protein (DUF2043); This is a 100 residue conserved region of a ...
 497-603 4.74e-59

Uncharacterized conserved protein (DUF2043); This is a 100 residue conserved region of a family of proteins found from fungi to humans. This region contains three conserved Cysteines and a motif of {CP}{y/l}{HG}.


Pssm-ID: 462871  Cd Length: 106  Bit Score: 194.35  E-value: 4.74e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034640801 497 ARAPVVPYGVDLHYWGQELpTAGKIVKSDSQ-HRFWKPSEVEEeVVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGR 575
Cdd:pfam09740   1 AKAPVVPFGLDLYYWGEEQ-EAGKVPKNNSGlHRFWGPSDVEE-VISAEKLAELNQRQITFAGKFEPVKHPCRAPLPNGG 78

                          90       100
                  ....*....|....*....|....*...
gi 1034640801 576 LCERQDRLKCPFHGKIVPRDDEGRPLDP 603
Cdd:pfam09740  79 LCPRRDRLKCPFHGKIIPRDDEGRPINP 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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