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Conserved domains on  [gi|767968061|ref|XP_011543289|]
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ankyrin repeat domain-containing protein 13D isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GPCR_chapero_1 pfam11904
GPCR-chaperone; This domain, and the associated ANK family repeat pfam00023 domain, together ...
68-431 2.54e-133

GPCR-chaperone; This domain, and the associated ANK family repeat pfam00023 domain, together act as a chaperone for biogenesis and folding of the DP receptor for prostaglandin D2.


:

Pssm-ID: 432178  Cd Length: 298  Bit Score: 390.07  E-value: 2.54e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061   68 RVDTSLLGFEHMTWQRGRRSFIFKGQ-EAGALVMEVDHDRQVVHVETLGLTLQEPEtllaamrpSEEHVASRLTSPIVST 146
Cdd:pfam11904   1 RADTTLLGFDGMKWQRGDQSFLFLGDgDSPGSLLELDHDDKEVQLEGAGAEASEEE--------VEEEVAARLQTPIVRT 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  147 HLDTRNVAFERNKCGiWGwRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKA-------GKTPFQSFLGMA 219
Cdd:pfam11904  73 GIDVTKISFERNKSG-WR-RQEKTETVGGYKAKVYDASNVVLSTKTRTEHLSEEEKKKLKSaleppegSRTPLQSFLGIV 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  220 QQHSSH-TGAPVQQAASPTNPTAISPEEYFDPnfslesrnigrPIEMSSKVQrpdelvrnpqepqpgpreegslghvart 298
Cdd:pfam11904 151 EEEKGWfGGKTRESTAPPTNPTAITPEEYFDP-----------PKEESEKKK---------------------------- 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  299 papggggqrhlsraghsrpgrRFKATLWLSEEHPLSLgDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFH 378
Cdd:pfam11904 192 ---------------------GFKATLWLSEDFPLSL-EQLLPILDLLANKVKHFRRLREFITLKLPPGFPVKIEIPVFP 249
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767968061  379 VLNARITFSNLCGCDePLSSVWVPAPSSavaASGNPFPCEVDPTVFEVPNGYS 431
Cdd:pfam11904 250 TVNARITFTKFEELE-PVEEFSTPIKSP---ERGSPSSCEIDDDPFEIPSGYT 298
 
Name Accession Description Interval E-value
GPCR_chapero_1 pfam11904
GPCR-chaperone; This domain, and the associated ANK family repeat pfam00023 domain, together ...
68-431 2.54e-133

GPCR-chaperone; This domain, and the associated ANK family repeat pfam00023 domain, together act as a chaperone for biogenesis and folding of the DP receptor for prostaglandin D2.


Pssm-ID: 432178  Cd Length: 298  Bit Score: 390.07  E-value: 2.54e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061   68 RVDTSLLGFEHMTWQRGRRSFIFKGQ-EAGALVMEVDHDRQVVHVETLGLTLQEPEtllaamrpSEEHVASRLTSPIVST 146
Cdd:pfam11904   1 RADTTLLGFDGMKWQRGDQSFLFLGDgDSPGSLLELDHDDKEVQLEGAGAEASEEE--------VEEEVAARLQTPIVRT 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  147 HLDTRNVAFERNKCGiWGwRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKA-------GKTPFQSFLGMA 219
Cdd:pfam11904  73 GIDVTKISFERNKSG-WR-RQEKTETVGGYKAKVYDASNVVLSTKTRTEHLSEEEKKKLKSaleppegSRTPLQSFLGIV 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  220 QQHSSH-TGAPVQQAASPTNPTAISPEEYFDPnfslesrnigrPIEMSSKVQrpdelvrnpqepqpgpreegslghvart 298
Cdd:pfam11904 151 EEEKGWfGGKTRESTAPPTNPTAITPEEYFDP-----------PKEESEKKK---------------------------- 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  299 papggggqrhlsraghsrpgrRFKATLWLSEEHPLSLgDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFH 378
Cdd:pfam11904 192 ---------------------GFKATLWLSEDFPLSL-EQLLPILDLLANKVKHFRRLREFITLKLPPGFPVKIEIPVFP 249
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767968061  379 VLNARITFSNLCGCDePLSSVWVPAPSSavaASGNPFPCEVDPTVFEVPNGYS 431
Cdd:pfam11904 250 TVNARITFTKFEELE-PVEEFSTPIKSP---ERGSPSSCEIDDDPFEIPSGYT 298
 
Name Accession Description Interval E-value
GPCR_chapero_1 pfam11904
GPCR-chaperone; This domain, and the associated ANK family repeat pfam00023 domain, together ...
68-431 2.54e-133

GPCR-chaperone; This domain, and the associated ANK family repeat pfam00023 domain, together act as a chaperone for biogenesis and folding of the DP receptor for prostaglandin D2.


Pssm-ID: 432178  Cd Length: 298  Bit Score: 390.07  E-value: 2.54e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061   68 RVDTSLLGFEHMTWQRGRRSFIFKGQ-EAGALVMEVDHDRQVVHVETLGLTLQEPEtllaamrpSEEHVASRLTSPIVST 146
Cdd:pfam11904   1 RADTTLLGFDGMKWQRGDQSFLFLGDgDSPGSLLELDHDDKEVQLEGAGAEASEEE--------VEEEVAARLQTPIVRT 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  147 HLDTRNVAFERNKCGiWGwRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKA-------GKTPFQSFLGMA 219
Cdd:pfam11904  73 GIDVTKISFERNKSG-WR-RQEKTETVGGYKAKVYDASNVVLSTKTRTEHLSEEEKKKLKSaleppegSRTPLQSFLGIV 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  220 QQHSSH-TGAPVQQAASPTNPTAISPEEYFDPnfslesrnigrPIEMSSKVQrpdelvrnpqepqpgpreegslghvart 298
Cdd:pfam11904 151 EEEKGWfGGKTRESTAPPTNPTAITPEEYFDP-----------PKEESEKKK---------------------------- 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968061  299 papggggqrhlsraghsrpgrRFKATLWLSEEHPLSLgDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFH 378
Cdd:pfam11904 192 ---------------------GFKATLWLSEDFPLSL-EQLLPILDLLANKVKHFRRLREFITLKLPPGFPVKIEIPVFP 249
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767968061  379 VLNARITFSNLCGCDePLSSVWVPAPSSavaASGNPFPCEVDPTVFEVPNGYS 431
Cdd:pfam11904 250 TVNARITFTKFEELE-PVEEFSTPIKSP---ERGSPSSCEIDDDPFEIPSGYT 298
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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