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Conserved domains on  [gi|767912548|ref|XP_011542539|]
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formin-2 isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FH2 super family cl19758
Formin Homology 2 Domain;
1287-1359 1.78e-12

Formin Homology 2 Domain;


The actual alignment was detected with superfamily member pfam02181:

Pssm-ID: 418645  Cd Length: 372  Bit Score: 70.76  E-value: 1.78e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767912548  1287 RKQPIEPCRPMKPLYWTRIqlhsKRDSSTSLIWEKIEEPS----IDCHEFEELFSKTAVKERKKPISDTISKTKAKQ 1359
Cdd:pfam02181    1 PKKTPKPKKKLKPLHWDKV----RPSQDRGTVWDKLDDESfeldGDLSELEELFSAKAKTKKNKKSEDKSSSKKKPK 73
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 229-395 4.50e-07

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLP 308
Cdd:PRK07764  622 AAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  309 AAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGD----TDEEGEEDAFEDAPRGSPGEEW--APEVGEDAPQRLGEEP 382
Cdd:PRK07764  702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDpvplPPEPDDPPDPAGAPAQPPPPPApaPAAAPAAAPPPSPPSE 781

                         170
                  ....*....|...
gi 767912548  383 EEEAQGPDAPAAA 395
Cdd:PRK07764  782 EEEMAEDDAPSMD 794
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 228-678 2.35e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 2.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA----PGSPdteqalsalsdlPESlaAEPREPQQPPSPGGLPVSE 303
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSrarrPDAP------------PQS--ARPRAPVDDRGDPRGPAPP 2614

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  304 APSLPAaqPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE-------DAFEDAPRGS-PGEEWAPEVGEDAP 375
Cdd:PHA03247 2615 SPLPPD--THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRvsrprraRRLGRAAQASsPPQRPRRRAARPTV 2692

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  376 QRLGE--EPEEEAQGPDAPAAASLPGSPAP----SQRCFKPYPLITPcyiktttrqLSSPNHSPSQSPNQSPRIKRRPEP 449
Cdd:PHA03247 2693 GSLTSlaDPPPPPPTPEPAPHALVSATPLPpgpaAARQASPALPAAP---------APPAVPAGPATPGGPARPARPPTT 2763

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  450 SLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAA 529
Cdd:PHA03247 2764 AGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP 2843

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  530 adgfqnvftgrtlleklfsqqenGPPEEAEKFCsriiamGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWA--AVSQP 607
Cdd:PHA03247 2844 -----------------------GPPPPSLPLG------GSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLArpAVSRS 2894

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  608 THSldysegqFPRRVPSMGPPSKPPDEEHRLEDAETEDDGESQSAvsETPQKRSDAVQKEVVDMKSEGQAT 678
Cdd:PHA03247 2895 TES-------FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP--PPPPPRPQPPLAPTTDPAGAGEPS 2956
 
Name Accession Description Interval E-value
FH2 pfam02181
Formin Homology 2 Domain;
1287-1359 1.78e-12

Formin Homology 2 Domain;


Pssm-ID: 396655  Cd Length: 372  Bit Score: 70.76  E-value: 1.78e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767912548  1287 RKQPIEPCRPMKPLYWTRIqlhsKRDSSTSLIWEKIEEPS----IDCHEFEELFSKTAVKERKKPISDTISKTKAKQ 1359
Cdd:pfam02181    1 PKKTPKPKKKLKPLHWDKV----RPSQDRGTVWDKLDDESfeldGDLSELEELFSAKAKTKKNKKSEDKSSSKKKPK 73
FH2 smart00498
Formin Homology 2 Domain; FH proteins control rearrangements of the actin cytoskeleton, ...
 1288-1359 1.06e-07

Formin Homology 2 Domain; FH proteins control rearrangements of the actin cytoskeleton, especially in the context of cytokinesis and cell polarisation. Members of this family have been found to interact with Rho-GTPases, profilin and other actin-assoziated proteins. These interactions are mediated by the proline-rich FH1 domain, usually located in front of FH2 (but not listed in SMART). Despite this cytosolic function, vertebrate formins have been assigned functions within the nucleus. A set of Formin-Binding Proteins (FBPs) has been shown to bind FH1 with their WW domain.


Pssm-ID: 214697 [Multi-domain]  Cd Length: 392  Bit Score: 55.82  E-value: 1.06e-07
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767912548   1288 KQPIEPCRPMKPLYWTRIQLHSKRDSstslIWEKIEEPSI-DCHEFEELFS-KTAVKERKKPISD--TISKTKAKQ 1359
Cdd:smart00498    1 KKEPKPKKKLKPLHWDKLNPSDLSGT----VWDKIDEESEgDLDELEELFSaKEKTKSASKDVSEkkSILKKKASQ 72
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 229-395 4.50e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLP 308
Cdd:PRK07764  622 AAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  309 AAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGD----TDEEGEEDAFEDAPRGSPGEEW--APEVGEDAPQRLGEEP 382
Cdd:PRK07764  702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDpvplPPEPDDPPDPAGAPAQPPPPPApaPAAAPAAAPPPSPPSE 781

                         170
                  ....*....|...
gi 767912548  383 EEEAQGPDAPAAA 395
Cdd:PRK07764  782 EEEMAEDDAPSMD 794
PHA03247 PHA03247
large tegument protein UL36; Provisional
 228-678 2.35e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 2.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA----PGSPdteqalsalsdlPESlaAEPREPQQPPSPGGLPVSE 303
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSrarrPDAP------------PQS--ARPRAPVDDRGDPRGPAPP 2614

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  304 APSLPAaqPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE-------DAFEDAPRGS-PGEEWAPEVGEDAP 375
Cdd:PHA03247 2615 SPLPPD--THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRvsrprraRRLGRAAQASsPPQRPRRRAARPTV 2692

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  376 QRLGE--EPEEEAQGPDAPAAASLPGSPAP----SQRCFKPYPLITPcyiktttrqLSSPNHSPSQSPNQSPRIKRRPEP 449
Cdd:PHA03247 2693 GSLTSlaDPPPPPPTPEPAPHALVSATPLPpgpaAARQASPALPAAP---------APPAVPAGPATPGGPARPARPPTT 2763

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  450 SLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAA 529
Cdd:PHA03247 2764 AGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP 2843

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  530 adgfqnvftgrtlleklfsqqenGPPEEAEKFCsriiamGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWA--AVSQP 607
Cdd:PHA03247 2844 -----------------------GPPPPSLPLG------GSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLArpAVSRS 2894

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  608 THSldysegqFPRRVPSMGPPSKPPDEEHRLEDAETEDDGESQSAvsETPQKRSDAVQKEVVDMKSEGQAT 678
Cdd:PHA03247 2895 TES-------FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP--PPPPPRPQPPLAPTTDPAGAGEPS 2956
SPS1 COG0515
Serine/threonine protein kinase [Signal transduction mechanisms];
186-406 4.00e-03

Serine/threonine protein kinase [Signal transduction mechanisms];


Pssm-ID: 440281 [Multi-domain]  Cd Length: 482  Bit Score: 41.54  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  186 FHSATEqedLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG 265
Cdd:COG0515   255 YQSAAE---LAAALRAVLRSLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAA 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  266 SPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345
Cdd:COG0515   332 AAAALAAAAAAAAAAAAAALLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAA 411

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406
Cdd:COG0515   412 AAAAAAAALAAAAAAAAAAAAAAAAAAAAAARLLAAAAAAAAAAAAAPLLAALLAAAALAA 472
 
Name Accession Description Interval E-value
FH2 pfam02181
Formin Homology 2 Domain;
1287-1359 1.78e-12

Formin Homology 2 Domain;


Pssm-ID: 396655  Cd Length: 372  Bit Score: 70.76  E-value: 1.78e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767912548  1287 RKQPIEPCRPMKPLYWTRIqlhsKRDSSTSLIWEKIEEPS----IDCHEFEELFSKTAVKERKKPISDTISKTKAKQ 1359
Cdd:pfam02181    1 PKKTPKPKKKLKPLHWDKV----RPSQDRGTVWDKLDDESfeldGDLSELEELFSAKAKTKKNKKSEDKSSSKKKPK 73
FH2 smart00498
Formin Homology 2 Domain; FH proteins control rearrangements of the actin cytoskeleton, ...
 1288-1359 1.06e-07

Formin Homology 2 Domain; FH proteins control rearrangements of the actin cytoskeleton, especially in the context of cytokinesis and cell polarisation. Members of this family have been found to interact with Rho-GTPases, profilin and other actin-assoziated proteins. These interactions are mediated by the proline-rich FH1 domain, usually located in front of FH2 (but not listed in SMART). Despite this cytosolic function, vertebrate formins have been assigned functions within the nucleus. A set of Formin-Binding Proteins (FBPs) has been shown to bind FH1 with their WW domain.


Pssm-ID: 214697 [Multi-domain]  Cd Length: 392  Bit Score: 55.82  E-value: 1.06e-07
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767912548   1288 KQPIEPCRPMKPLYWTRIQLHSKRDSstslIWEKIEEPSI-DCHEFEELFS-KTAVKERKKPISD--TISKTKAKQ 1359
Cdd:smart00498    1 KKEPKPKKKLKPLHWDKLNPSDLSGT----VWDKIDEESEgDLDELEELFSaKEKTKSASKDVSEkkSILKKKASQ 72
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 229-395 4.50e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLP 308
Cdd:PRK07764  622 AAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  309 AAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGD----TDEEGEEDAFEDAPRGSPGEEW--APEVGEDAPQRLGEEP 382
Cdd:PRK07764  702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDpvplPPEPDDPPDPAGAPAQPPPPPApaPAAAPAAAPPPSPPSE 781

                         170
                  ....*....|...
gi 767912548  383 EEEAQGPDAPAAA 395
Cdd:PRK07764  782 EEEMAEDDAPSMD 794
PHA03247 PHA03247
large tegument protein UL36; Provisional
 233-467 1.71e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.02  E-value: 1.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  233 AAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALS-------------ALSDLPESLAAEPREPQQPPSPGGL 299
Cdd:PHA03247 2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPApgrvsrprrarrlGRAAQASSPPQRPRRRAARPTVGSL 2695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  300 PVSEAPSLPAAQPAAKDSPSSTAFPFP--EAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQR 377
Cdd:PHA03247 2696 TSLADPPPPPPTPEPAPHALVSATPLPpgPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  378 LGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS-PNQSPRIKRRPEPSLSRG-- 454
Cdd:PHA03247 2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqPTAPPPPPGPPPPSLPLGgs 2855

                         250       260
                  ....*....|....*....|....*
gi 767912548  455 ------------SRTALASVAAPAK 467
Cdd:PHA03247 2856 vapggdvrrrppSRSPAAKPAAPAR 2880
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 263-406 2.06e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 52.30  E-value: 2.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  263 APGSPDTEQALSALSDLPES---LAAEPREPQQPPsPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPV 339
Cdd:PRK07764  364 LPSASDDERGLLARLERLERrlgVAGGAGAPAAAA-PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPP 442

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767912548  340 rGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPA-----AASLPGSPAPSQR 406
Cdd:PRK07764  443 -SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAapaapAAPAGADDAATLR 513
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
232-412 2.14e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 52.19  E-value: 2.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  232 PAAPPTAVSPQPGAFLGldrfllGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPA-A 310
Cdd:PRK12323  388 AAAAPAAAAPAPAAPPA------APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAaA 461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  311 QPAAKDSPSSTAFPFPEAGPGEEAAGAPVrgAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDA-----PQRLGEEPEEE 385
Cdd:PRK12323  462 ARPAAAGPRPVAAAAAAAPARAAPAAAPA--PADDDPPPWEELPPEFASPAPAQPDAAPAGWVAesipdPATADPDDAFE 539

                         170       180
                  ....*....|....*....|....*..
gi 767912548  386 AQGPdAPAAASLPGSPAPSQRCFKPYP 412
Cdd:PRK12323  540 TLAP-APAAAPAPRAAAATEPVVAPRP 565
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 230-513 4.69e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 51.33  E-value: 4.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  230 EEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPES-----LAAEPREPQQPPSPGG--LPVS 302
Cdd:PHA03307  117 PPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSrqaalPLSSPEETARAPSSPPaePPPS 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  303 EAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT----DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRL 378
Cdd:PHA03307  197 TPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSssseSSGCGWGPENECPLPRPAPITLPTRIWEASGWN 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  379 GEEPEEEAQGPDAPAAASLPgSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTA 458
Cdd:PHA03307  277 GPSSRPGPASSSSSPRERSP-SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR 355

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767912548  459 LASVAAPAKKHRADGGLAAGLSRSADwteelGARTPRVGGSAHLLERGVASDSGG 513
Cdd:PHA03307  356 PPPPADPSSPRKRPRPSRAPSSPAAS-----AGRPTRRRARAAVAGRARRRDATG 405
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
228-402 6.93e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 50.62  E-value: 6.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  228 GAEEPAAPPTAV-SPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSdlPESLAAEPREPQQPPSpgGLPVSEAPS 306
Cdd:PRK07003  369 GGGVPARVAGAVpAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAA--ATRAEAPPAAPAPPAT--ADRGDDAAD 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  307 LPAAQPAAKDSPSSTAFPFPEAGPgeEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEA 386
Cdd:PRK07003  445 GDAPVPAKANARASADSRCDERDA--QPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAP 522

                         170
                  ....*....|....*.
gi 767912548  387 QGPDAPAAASLPGSPA 402
Cdd:PRK07003  523 AAAAPPAPEARPPTPA 538
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 293-406 9.82e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.98  E-value: 9.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  293 PPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGE 372
Cdd:PRK07764  596 GGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767912548  373 DAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406
Cdd:PRK07764  676 AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP 709
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
229-402 1.56e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 49.49  E-value: 1.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPdteqalsalsdlpeSLAAEPREPQQPPSPGGLPVSEAPSLP 308
Cdd:PRK12323  416 ARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAP--------------AAAPAAAARPAAAGPRPVAAAAAAAPA 481

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  309 AAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRG----AGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEE 384
Cdd:PRK12323  482 RAAPAAAPAPADDDPPPWEELPPEFASPAPAQPdaapAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561

                         170
                  ....*....|....*...
gi 767912548  385 EAQGPDAPAAASLPGSPA 402
Cdd:PRK12323  562 APRPPRASASGLPDMFDG 579
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 136-385 2.00e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.21  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  136 ADPFEVTGPGGPGPAEArvGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSAteqedllsdiqQAIRLQQQQQQQLQL 215
Cdd:PRK07764  595 AGGEGPPAPASSGPPEE--AARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPG-----------VAAPEHHPKHVAVPD 661

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  216 QLQQQQQQQQLQGAEEPAAPPTAVSPQPgaflgldrfllgPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQ--- 292
Cdd:PRK07764  662 ASDGGDGWPAKAGGAAPAAPPPAPAPAA------------PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQgas 729

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  293 PPSPGGLPVSEAPSLPAAQPAAKDSPSSTAfpfPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGE 372
Cdd:PRK07764  730 APSPAADDPVPLPPEPDDPPDPAGAPAQPP---PPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAM 806

                         250
                  ....*....|....
gi 767912548  373 DAPQR-LGEEPEEE 385
Cdd:PRK07764  807 ELLEEeLGAKKIEE 820
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
228-441 2.35e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 49.08  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  228 GAEEPAAPPTAVSP-QPGAFLGLDRFLLGPSGGAGEAPGSPDT-------------EQALSALSDLPESLAAEPREPQQP 293
Cdd:PRK07003  419 AATRAEAPPAAPAPpATADRGDDAADGDAPVPAKANARASADSrcderdaqppadsGSASAPASDAPPDAAFEPAPRAAA 498

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  294 PSPGGLPVSEAPSLPAAQPAAkDSPSSTAFPFPEAGPGEEAAGAPVRGAGdtdeegeedafedaprgspGEEWAPEVGED 373
Cdd:PRK07003  499 PSAATPAAVPDARAPAAASRE-DAPAAAAPPAPEARPPTPAAAAPAARAG-------------------GAAAALDVLRN 558

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767912548  374 APQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYP-LITPCYIKTTTRQLSSPNHSPSQSPNQSP 441
Cdd:PRK07003  559 AGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPtPRARAATGDAPPNGAARAEQAAESRGAPP 627
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 258-483 2.86e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 48.63  E-value: 2.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  258 GGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPfpeAGPGEEAAGA 337
Cdd:PHA03307  109 PGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LSSPEETARA 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  338 PVRGAGDTDEEGEEDAFEDAPRGsPGEEWAPEVGEDAPqRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPC 417
Cdd:PHA03307  186 PSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAP-APGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPI 263

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  418 YIKTTTRQLSSPNH----SPSQSPNQSPRIKR-RPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSA 483
Cdd:PHA03307  264 TLPTRIWEASGWNGpssrPGPASSSSSPRERSpSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSE 334
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
254-491 6.82e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 47.18  E-value: 6.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  254 LGPSGGAGEA-PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGE 332
Cdd:PRK12323  363 FRPGQSGGGAgPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASAR 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  333 EAAGAPVRGAGDTDEEGEEdafedAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPG---SPAPSQRCFK 409
Cdd:PRK12323  443 GPGGAPAPAPAPAAAPAAA-----ARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPefaSPAPAQPDAA 517

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  410 PYPLITPCYIKTTTRQLSSPNHSPSQSPNQS--PRIKRRPEPSLSRGSRTALASVAAPAKKHRADG--------GLAAGL 479
Cdd:PRK12323  518 PAGWVAESIPDPATADPDDAFETLAPAPAAApaPRAAAATEPVVAPRPPRASASGLPDMFDGDWPAlaarlpvrGLAQQL 597

                         250
                  ....*....|..
gi 767912548  480 SRSADWTEELGA 491
Cdd:PRK12323  598 ARQSELAGVEGD 609
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 252-342 5.65e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 44.50  E-value: 5.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  252 FLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGglPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPG 331
Cdd:PRK12270   32 FFADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAA--AAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPA 109

                          90
                  ....*....|....
gi 767912548  332 EEAAGA---PVRGA 342
Cdd:PRK12270  110 AAAVEDevtPLRGA 123
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
256-477 6.71e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.07  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  256 PSGGAGEAPG---SPDTEQALSALSDLPESLAAEPREPQQPPSPGglPVSEAPSLPAAQPAAkdspsSTAFPFPEAGPGE 332
Cdd:PRK07003  360 PAVTGGGAPGggvPARVAGAVPAPGARAAAAVGASAVPAVTAVTG--AAGAALAPKAAAAAA-----ATRAEAPPAAPAP 432

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  333 EAAGapvrgagdtdEEGEEDAFEDAPRGSPGEewAPEVGEDAPQRLGEEPeeeaqgPDAPAAASLPGSPAPSQRCFKPYP 412
Cdd:PRK07003  433 PATA----------DRGDDAADGDAPVPAKAN--ARASADSRCDERDAQP------PADSGSASAPASDAPPDAAFEPAP 494

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767912548  413 LITPCYIKTttrqlsSPNHSPSQSPNQSPRIKrRPEPSLSRGSRTALASVAAPAKKHRADGGLAA 477
Cdd:PRK07003  495 RAAAPSAAT------PAAVPDARAPAAASRED-APAAAAPPAPEARPPTPAAAAPAARAGGAAAA 552
PHA03247 PHA03247
large tegument protein UL36; Provisional
 228-678 2.35e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 2.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA----PGSPdteqalsalsdlPESlaAEPREPQQPPSPGGLPVSE 303
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSrarrPDAP------------PQS--ARPRAPVDDRGDPRGPAPP 2614

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  304 APSLPAaqPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE-------DAFEDAPRGS-PGEEWAPEVGEDAP 375
Cdd:PHA03247 2615 SPLPPD--THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRvsrprraRRLGRAAQASsPPQRPRRRAARPTV 2692

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  376 QRLGE--EPEEEAQGPDAPAAASLPGSPAP----SQRCFKPYPLITPcyiktttrqLSSPNHSPSQSPNQSPRIKRRPEP 449
Cdd:PHA03247 2693 GSLTSlaDPPPPPPTPEPAPHALVSATPLPpgpaAARQASPALPAAP---------APPAVPAGPATPGGPARPARPPTT 2763

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  450 SLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAA 529
Cdd:PHA03247 2764 AGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP 2843

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  530 adgfqnvftgrtlleklfsqqenGPPEEAEKFCsriiamGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWA--AVSQP 607
Cdd:PHA03247 2844 -----------------------GPPPPSLPLG------GSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLArpAVSRS 2894

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  608 THSldysegqFPRRVPSMGPPSKPPDEEHRLEDAETEDDGESQSAvsETPQKRSDAVQKEVVDMKSEGQAT 678
Cdd:PHA03247 2895 TES-------FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP--PPPPPRPQPPLAPTTDPAGAGEPS 2956
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 256-406 2.61e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.01  E-value: 2.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  256 PSGGAGEAPGSPdteqalsalsdlPESLAaepREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTafPFPEAGPGEEAA 335
Cdd:PRK14951  366 PAAAAEAAAPAE------------KKTPA---RPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAA--PPAAAPPAPVAA 428

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  336 GAPVRGAGdtdeegeedAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406
Cdd:PRK14951  429 PAAAAPAA---------APAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 232-514 2.89e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 2.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  232 PAAPPTAVSPQPGAflgldrflLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLP--VSEAPSLPA 309
Cdd:PRK07764  402 AAAAPAAAPAPAAA--------APAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPsaQPAPAPAAA 473

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  310 AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTD------------------------------------------- 346
Cdd:PRK07764  474 PEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAtlrerwpeilaavpkrsrktwaillpeatvlgvrgdtlvlgfs 553

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  347 ---------EEGEEDAFEDAPRGSPGEEWAPE--VGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFkPYPLIT 415
Cdd:PRK07764  554 tgglarrfaSPGNAEVLVTALAEELGGDWQVEavVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA-PAPAGA 632

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  416 PcyikTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKK--------HRADGGLAAGLSRSADWTE 487
Cdd:PRK07764  633 A----AAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPppapapaaPAAPAGAAPAQPAPAPAAT 708

                         330       340
                  ....*....|....*....|....*..
gi 767912548  488 ELGARTPRVGGSAHLLERGVASDSGGG 514
Cdd:PRK07764  709 PPAGQADDPAAQPPQAAQGASAPSPAA 735
PHA03247 PHA03247
large tegument protein UL36; Provisional
 228-467 3.08e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 3.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  228 GAEEPAAPPTAVSPQPGAFlgldrfllgpsggAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL 307
Cdd:PHA03247 2502 GPPDPDAPPAPSRLAPAIL-------------PDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSV 2568

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  308 PAAQPAAKdsPSSTAFPFPEAGPGEEAAGAPVRGAGDtdeegeedafedaPRGSPGEEWAPEVGEDAPQRLGEEPeeeaq 387
Cdd:PHA03247 2569 PPPRPAPR--PSEPAVTSRARRPDAPPQSARPRAPVD-------------DRGDPRGPAPPSPLPPDTHAPDPPP----- 2628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  388 gPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQsPNQSPRIKRRPEPSLSRGSRTALASVAAPAK 467
Cdd:PHA03247 2629 -PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQ-ASSPPQRPRRRAARPTVGSLTSLADPPPPPP 2706
SPS1 COG0515
Serine/threonine protein kinase [Signal transduction mechanisms];
186-406 4.00e-03

Serine/threonine protein kinase [Signal transduction mechanisms];


Pssm-ID: 440281 [Multi-domain]  Cd Length: 482  Bit Score: 41.54  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  186 FHSATEqedLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG 265
Cdd:COG0515   255 YQSAAE---LAAALRAVLRSLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAA 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  266 SPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345
Cdd:COG0515   332 AAAALAAAAAAAAAAAAAALLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAA 411

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767912548  346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406
Cdd:COG0515   412 AAAAAAAALAAAAAAAAAAAAAAAAAAAAAARLLAAAAAAAAAAAAAPLLAALLAAAALAA 472
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 255-403 5.99e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 5.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  255 GPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPS-PGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEE 333
Cdd:PRK07764  594 AAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAaPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKA 673

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912548  334 AAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPeEEAQGPDAPAAASLPGSPAP 403
Cdd:PRK07764  674 GGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPP-QAAQGASAPSPAADDPVPLP 742
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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