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Conserved domains on  [gi|755537405|ref|XP_011247047|]
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huntingtin-associated protein 1 isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HAP1_N super family cl25919
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 80-403 7.01e-117

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


The actual alignment was detected with superfamily member pfam04849:

Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 350.48  E-value: 7.01e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405   80 YVFQGPYGPRATGLGTGKAEGIWKTPAAYiGRRPGVSGPERAAFIRELQE--ALCPNPPPTKKITEDDVKVMLYLLEEKE 157
Cdd:pfam04849   1 EEQIPPYKLRADTLGTGYANQDWKIPSPA-GRPPEVSLPLSPEQIRETLNyfLLCSDRVSQMTKTYNDIEAVTRLLEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  158 RDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDDDDDEEDEEDEEEGEEEEReg 237
Cdd:pfam04849  80 RDLELAARIGQSLLKQNSVLTERNEALEEQLGSAREEILQLRHELSKKDDLLQIYSNDAEESETESSCSTPLRRNESF-- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  238 qrdqdqqhdhpygapkphpkaETAHRCPQLETLQQKLRLLEEENDHLREEASHL----DNLEDEEQMLILECVEQFSEAS 313
Cdd:pfam04849 158 ---------------------SSLHGCVQLDALQEKLRGLEEENLKLRSEASHLktetDTYEEKEQQLMSDCVEQLSEAN 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  314 QQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQMLASEKGIHseQSLRagSYMQDYGSRP--- 390
Cdd:pfam04849 217 QQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEELQQHLQASKEAQ--RQLT--SELQELQDRYaec 292

                         330
                  ....*....|....*..
gi 755537405  391 ----RDRQEDGKSHRQR 403
Cdd:pfam04849 293 lgmlHEAQEELKELRKK 309
 
Name Accession Description Interval E-value
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 80-403 7.01e-117

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 350.48  E-value: 7.01e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405   80 YVFQGPYGPRATGLGTGKAEGIWKTPAAYiGRRPGVSGPERAAFIRELQE--ALCPNPPPTKKITEDDVKVMLYLLEEKE 157
Cdd:pfam04849   1 EEQIPPYKLRADTLGTGYANQDWKIPSPA-GRPPEVSLPLSPEQIRETLNyfLLCSDRVSQMTKTYNDIEAVTRLLEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  158 RDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDDDDDEEDEEDEEEGEEEEReg 237
Cdd:pfam04849  80 RDLELAARIGQSLLKQNSVLTERNEALEEQLGSAREEILQLRHELSKKDDLLQIYSNDAEESETESSCSTPLRRNESF-- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  238 qrdqdqqhdhpygapkphpkaETAHRCPQLETLQQKLRLLEEENDHLREEASHL----DNLEDEEQMLILECVEQFSEAS 313
Cdd:pfam04849 158 ---------------------SSLHGCVQLDALQEKLRGLEEENLKLRSEASHLktetDTYEEKEQQLMSDCVEQLSEAN 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  314 QQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQMLASEKGIHseQSLRagSYMQDYGSRP--- 390
Cdd:pfam04849 217 QQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEELQQHLQASKEAQ--RQLT--SELQELQDRYaec 292

                         330
                  ....*....|....*..
gi 755537405  391 ----RDRQEDGKSHRQR 403
Cdd:pfam04849 293 lgmlHEAQEELKELRKK 309
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
266-369 8.39e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 8.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405 266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQMLILECVEQFSEASQQMAELSEVLvlrLEGYERQQKEITQLQAEIT 345
Cdd:COG4717  140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL---AEELEELQQRLAELEEELE 216

                         90       100
                 ....*....|....*....|....
gi 755537405 346 KLQQRCQSYGAQTEKLQQMLASEK 369
Cdd:COG4717  217 EAQEELEELEEELEQLENELEAAA 240
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 266-347 5.06e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 5.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405   266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQ-QKEITQLQAEI 344
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEaRRRLKRLENKI 981


                   ...
gi 755537405   345 TKL 347
Cdd:TIGR02168  982 KEL 984
mukB PRK04863
chromosome partition protein MukB;
266-404 7.59e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 39.56  E-value: 7.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  266 QLETLQQKLRLLEEEndhLREEASHLDNLEDEEQMLIL-----ECVEQF-SEASQQMAELSEVLVLRLEGYERQQKEITQ 339
Cdd:PRK04863  514 QLQQLRMRLSELEQR---LRQQQRAERLLAEFCKRLGKnlddeDELEQLqEELEARLESLSESVSEARERRMALRQQLEQ 590

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755537405  340 LQAEITKLQQRCQSYGAQTEKLQQmLASEKGIHSEQSLRAGSYMQDYGSRPRD--RQEDGKSHRQRS 404
Cdd:PRK04863  591 LQARIQRLAARAPAWLAAQDALAR-LREQSGEEFEDSQDVTEYMQQLLEREREltVERDELAARKQA 656
 
Name Accession Description Interval E-value
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 80-403 7.01e-117

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 350.48  E-value: 7.01e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405   80 YVFQGPYGPRATGLGTGKAEGIWKTPAAYiGRRPGVSGPERAAFIRELQE--ALCPNPPPTKKITEDDVKVMLYLLEEKE 157
Cdd:pfam04849   1 EEQIPPYKLRADTLGTGYANQDWKIPSPA-GRPPEVSLPLSPEQIRETLNyfLLCSDRVSQMTKTYNDIEAVTRLLEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  158 RDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDDDDDEEDEEDEEEGEEEEReg 237
Cdd:pfam04849  80 RDLELAARIGQSLLKQNSVLTERNEALEEQLGSAREEILQLRHELSKKDDLLQIYSNDAEESETESSCSTPLRRNESF-- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  238 qrdqdqqhdhpygapkphpkaETAHRCPQLETLQQKLRLLEEENDHLREEASHL----DNLEDEEQMLILECVEQFSEAS 313
Cdd:pfam04849 158 ---------------------SSLHGCVQLDALQEKLRGLEEENLKLRSEASHLktetDTYEEKEQQLMSDCVEQLSEAN 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  314 QQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQMLASEKGIHseQSLRagSYMQDYGSRP--- 390
Cdd:pfam04849 217 QQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEELQQHLQASKEAQ--RQLT--SELQELQDRYaec 292

                         330
                  ....*....|....*..
gi 755537405  391 ----RDRQEDGKSHRQR 403
Cdd:pfam04849 293 lgmlHEAQEELKELRKK 309
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
266-369 8.39e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 8.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405 266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQMLILECVEQFSEASQQMAELSEVLvlrLEGYERQQKEITQLQAEIT 345
Cdd:COG4717  140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL---AEELEELQQRLAELEEELE 216

                         90       100
                 ....*....|....*....|....
gi 755537405 346 KLQQRCQSYGAQTEKLQQMLASEK 369
Cdd:COG4717  217 EAQEELEELEEELEQLENELEAAA 240
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 145-379 2.16e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 2.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405 145 DVKVMLYLLEEKERDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRddLLQLYSDSDDDDDEEDE 224
Cdd:COG1196  226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA--QAEEYELLAELARLEQD 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405 225 EDEEEGEEEEREGQRDQDQQhdhpygapkphpkaetahrcpQLETLQQKLRLLEEENDHLREEASHLDNLEDEEQMLILE 304
Cdd:COG1196  304 IARLEERRRELEERLEELEE---------------------ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755537405 305 CVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQsygaQTEKLQQMLASEKGIHSEQSLRA 379
Cdd:COG1196  363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE----ALLERLERLEEELEELEEALAEL 433
FlgN pfam05130
FlgN protein; This family includes the FlgN protein and export chaperone involved in flagellar ...
 266-352 5.80e-04

FlgN protein; This family includes the FlgN protein and export chaperone involved in flagellar synthesis.


Pssm-ID: 428323 [Multi-domain]  Cd Length: 140  Bit Score: 40.43  E-value: 5.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  266 QLETLQQKLRLLEEENDHLRE-EASHLDNLEDEEQmlilECVEQFSEASQQMAELSEVLVLRLEG--------YERQQKE 336
Cdd:pfam05130  10 ELELLEELLELLEEEQEALKAgDIEALEELTEEKQ----ELLQKLAQLEKERRELLAELGLSPEEatlsellaKEEEDPE 85

                          90
                  ....*....|....*.
gi 755537405  337 ITQLQAEITKLQQRCQ 352
Cdd:pfam05130  86 LRELWQELLELLERLK 101
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
266-371 7.37e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 7.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  266 QLETLQQKLRLLEEENDHLREEASHLDNL-----------EDEEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQ 334
Cdd:COG4913   339 RLEQLEREIERLERELEERERRRARLEALlaalglplpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 755537405  335 KEITQLQAEITKLQQRCQSYGAQTEKLQQMLASEKGI 371
Cdd:COG4913   419 RELRELEAEIASLERRKSNIPARLLALRDALAEALGL 455
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
266-379 3.76e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.28  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQmlilECVEQFSEASQQMAELsevlvlrlegyerqQKEITQLQAEIT 345
Cdd:COG4913   669 EIAELEAELERLDASSDDLAALEEQLEELEAELE----ELEEELDELKGEIGRL--------------EKELEQAEEELD 730

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 755537405  346 KLQQRCQSYG-----AQTEKLQQMLASEKGIHSEQSLRA 379
Cdd:COG4913   731 ELQDRLEAAEdlarlELRALLEERFAAALGDAVERELRE 769
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 266-347 5.06e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 5.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405   266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQ-QKEITQLQAEI 344
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEaRRRLKRLENKI 981


                   ...
gi 755537405   345 TKL 347
Cdd:TIGR02168  982 KEL 984
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
266-369 7.55e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.12  E-value: 7.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405 266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQMLILECVEQFSEASQQMAELSEVLVLRLE-------GYERQQKEIT 338
Cdd:COG4372   39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEeleslqeEAEELQEELE 118

                         90       100       110
                 ....*....|....*....|....*....|.
gi 755537405 339 QLQAEITKLQQRCQSYGAQTEKLQQMLASEK 369
Cdd:COG4372  119 ELQKERQDLEQQRKQLEAQIAELQSEIAERE 149
mukB PRK04863
chromosome partition protein MukB;
266-404 7.59e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 39.56  E-value: 7.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405  266 QLETLQQKLRLLEEEndhLREEASHLDNLEDEEQMLIL-----ECVEQF-SEASQQMAELSEVLVLRLEGYERQQKEITQ 339
Cdd:PRK04863  514 QLQQLRMRLSELEQR---LRQQQRAERLLAEFCKRLGKnlddeDELEQLqEELEARLESLSESVSEARERRMALRQQLEQ 590

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755537405  340 LQAEITKLQQRCQSYGAQTEKLQQmLASEKGIHSEQSLRAGSYMQDYGSRPRD--RQEDGKSHRQRS 404
Cdd:PRK04863  591 LQARIQRLAARAPAWLAAQDALAR-LREQSGEEFEDSQDVTEYMQQLLEREREltVERDELAARKQA 656
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 266-366 7.82e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 7.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405   266 QLETLQQKLRLLEEEndhlreeashLDNLEDEEQML---ILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQA 342
Cdd:TIGR02168  324 QLEELESKLDELAEE----------LAELEEKLEELkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                           90       100
                   ....*....|....*....|....
gi 755537405   343 EITKLQQRCQSYGAQTEKLQQMLA 366
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRE 417
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
266-385 9.77e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.98  E-value: 9.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755537405 266 QLETLQQKLRLLEEENDHLREEASHLDNLEDEEQML---------ILECVEQFSEASQQMAELSEvLVLRLEGYERQQKE 336
Cdd:COG4717   72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELeaeleelreELEKLEKLLQLLPLYQELEA-LEAELAELPERLEE 150

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 755537405 337 ITQLQAEITKLQQRCQSYGAQTEKLQQMLASEKGIHSEQSLRAGSYMQD 385
Cdd:COG4717  151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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