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Conserved domains on  [gi|755542723|ref|XP_011242422|]
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kelch domain-containing protein 1 isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-282 2.45e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.70  E-value: 2.45e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  18 GELPPSMSGSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRdgtyTWEKITKFdgqPPTPRDKLSCWVYKDRLIYFGGY 97
Cdd:COG3055    7 PDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN----TWSELAPL---PGPPRHHAAAVAQDGKLYVFGGF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  98 GYRRHSelqecfdvhdasweeqifWGWHNDVHVFDTKTRTWSqpeiKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMN 177
Cdd:COG3055   80 TGANPS------------------STPLNDVYVYDPATNTWT----KLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 178 DLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAITDDKLFLFGGLNADniplsdgwihnITTNCWKQLRHLPYtrPRLWH 257
Cdd:COG3055  138 WVEVYDPATGTW----TQLAPLPTPRDHLAAAVLPDGKILVIGGRNGS-----------GFSNTWTTLAPLPT--ARAGH 200

                        250       260
                 ....*....|....*....|....*...
gi 755542723 258 TACLGKeNEIMVFGGSK---DNLLFLDT 282
Cdd:COG3055  201 AAAVLG-GKILVFGGESgfsDEVEAYDP 227
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-282 2.45e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.70  E-value: 2.45e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  18 GELPPSMSGSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRdgtyTWEKITKFdgqPPTPRDKLSCWVYKDRLIYFGGY 97
Cdd:COG3055    7 PDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN----TWSELAPL---PGPPRHHAAAVAQDGKLYVFGGF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  98 GYRRHSelqecfdvhdasweeqifWGWHNDVHVFDTKTRTWSqpeiKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMN 177
Cdd:COG3055   80 TGANPS------------------STPLNDVYVYDPATNTWT----KLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 178 DLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAITDDKLFLFGGLNADniplsdgwihnITTNCWKQLRHLPYtrPRLWH 257
Cdd:COG3055  138 WVEVYDPATGTW----TQLAPLPTPRDHLAAAVLPDGKILVIGGRNGS-----------GFSNTWTTLAPLPT--ARAGH 200

                        250       260
                 ....*....|....*....|....*...
gi 755542723 258 TACLGKeNEIMVFGGSK---DNLLFLDT 282
Cdd:COG3055  201 AAAVLG-GKILVFGGESgfsDEVEAYDP 227
PLN02153 PLN02153
epithiospecifier protein
 138-278 3.14e-12

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 66.93  E-value: 3.14e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 138 WSQPEIKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRM--NDLHYLNLDTWVWSgRISVNGESPKHRSWHTLTAITDDK 215
Cdd:PLN02153   9 WIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGELKPNEHidKDLYVFDFNTHTWS-IAPANGDVPRISCLGVRMVAVGTK 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755542723 216 LFLFGGLNAdNIPLSDGWIHNITTNCWKQLRHLPYT---RPRLWHTAClGKENEIMVFGG-SKDNLL 278
Cdd:PLN02153  88 LYIFGGRDE-KREFSDFYSYDTVKNEWTFLTKLDEEggpEARTFHSMA-SDENHVYVFGGvSKGGLM 152
Kelch_4 pfam13418
Galactose oxidase, central domain;
202-250 1.43e-09

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 53.00  E-value: 1.43e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755542723  202 HRSWHTLTAITDDKLFLFGGLNADNIPLSDGWIHNITTNCWKQLRHLPY 250
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-282 2.45e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.70  E-value: 2.45e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  18 GELPPSMSGSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRdgtyTWEKITKFdgqPPTPRDKLSCWVYKDRLIYFGGY 97
Cdd:COG3055    7 PDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN----TWSELAPL---PGPPRHHAAAVAQDGKLYVFGGF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  98 GYRRHSelqecfdvhdasweeqifWGWHNDVHVFDTKTRTWSqpeiKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMN 177
Cdd:COG3055   80 TGANPS------------------STPLNDVYVYDPATNTWT----KLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 178 DLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAITDDKLFLFGGLNADniplsdgwihnITTNCWKQLRHLPYtrPRLWH 257
Cdd:COG3055  138 WVEVYDPATGTW----TQLAPLPTPRDHLAAAVLPDGKILVIGGRNGS-----------GFSNTWTTLAPLPT--ARAGH 200

                        250       260
                 ....*....|....*....|....*...
gi 755542723 258 TACLGKeNEIMVFGGSK---DNLLFLDT 282
Cdd:COG3055  201 AAAVLG-GKILVFGGESgfsDEVEAYDP 227
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
137-276 3.02e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 86.36  E-value: 3.02e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 137 TWSQpeikGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAITDDKL 216
Cdd:COG3055    2 TWSS----LPDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTW----SELAPLPGPPRHHAAAVAQDGKL 73

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755542723 217 FLFGGLNADN---IPLSDGWIHNITTNCWKQLRHLPytRPRLWHTACLgKENEIMVFGGSKDN 276
Cdd:COG3055   74 YVFGGFTGANpssTPLNDVYVYDPATNTWTKLAPMP--TPRGGATALL-LDGKIYVVGGWDDG 133
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
2-169 1.94e-15

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 75.58  E-value: 1.94e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723   2 WTYDIDSGLWKMHlmeGELPPSMSGSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRdgtyTWEKITKFdgqpPTPRDK 81
Cdd:COG3055   93 YVYDPATNTWTKL---APMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATG----TWTQLAPL----PTPRDH 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  82 LSCWV-YKDRLIYFGGYGYRRHSE--------LQECFDVHDASWEEQIF-----WGWHNDVHVFDTKTRTWSQpeikGGV 147
Cdd:COG3055  162 LAAAVlPDGKILVIGGRNGSGFSNtwttlaplPTARAGHAAAVLGGKILvfggeSGFSDEVEAYDPATNTWTA----LGE 237

                        170       180
                 ....*....|....*....|..
gi 755542723 148 PPQPRAAHSCAVLGNKGYVFGG 169
Cdd:COG3055  238 LPTPRHGHAAVLTDGKVYVIGG 259
PLN02153 PLN02153
epithiospecifier protein
 138-278 3.14e-12

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 66.93  E-value: 3.14e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 138 WSQPEIKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRM--NDLHYLNLDTWVWSgRISVNGESPKHRSWHTLTAITDDK 215
Cdd:PLN02153   9 WIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGELKPNEHidKDLYVFDFNTHTWS-IAPANGDVPRISCLGVRMVAVGTK 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755542723 216 LFLFGGLNAdNIPLSDGWIHNITTNCWKQLRHLPYT---RPRLWHTAClGKENEIMVFGG-SKDNLL 278
Cdd:PLN02153  88 LYIFGGRDE-KREFSDFYSYDTVKNEWTFLTKLDEEggpEARTFHSMA-SDENHVYVFGGvSKGGLM 152
PLN02193 PLN02193
nitrile-specifier protein
 1-237 4.68e-12

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 66.90  E-value: 4.68e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723   1 MWTYDIDSGLWKMHLMEGELPP-SMSGSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRDgtytWEKITKFDgQPPTPR 79
Cdd:PLN02193 195 LYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGRDASRQYNGFYSFDTTTNE----WKLLTPVE-EGPTPR 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  80 DKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASW-----------------------EEQIFWGWH----NDVHVFD 132
Cdd:PLN02193 270 SFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKWfhcstpgdsfsirggaglevvqgKVWVVYGFNgcevDDVHYYD 349

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 133 TKTRTWSQPEiKGGVPPQPRAAHSCAVLGNKGYVFGGRVlqtRMNDLHYLN----------LDT----WVWSGRISVNGE 198
Cdd:PLN02193 350 PVQDKWTQVE-TFGVRPSERSVFASAAVGKHIVIFGGEI---AMDPLAHVGpgqltdgtfaLDTetlqWERLDKFGEEEE 425

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 755542723 199 SPKHRSWHTLTAITDD---KLFLFGGLNADNIPLSDGWIHNI 237
Cdd:PLN02193 426 TPSSRGWTASTTGTIDgkkGLVMHGGKAPTNDRFDDLFFYGI 467
PLN02153 PLN02153
epithiospecifier protein
 65-245 8.49e-10

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 59.61  E-value: 8.49e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  65 WEKITKFDGQPPTPRDKLSCWVYKDRLIYFGGygyrrhsELQEcfdvhdaswEEQIfwgwHNDVHVFDTKTRTWSQPEIK 144
Cdd:PLN02153   9 WIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGG-------ELKP---------NEHI----DKDLYVFDFNTHTWSIAPAN 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 145 GGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHylNLDT----WVWSGRISVNGeSPKHRSWHTLTAiTDDKLFLFG 220
Cdd:PLN02153  69 GDVPRISCLGVRMVAVGTKLYIFGGRDEKREFSDFY--SYDTvkneWTFLTKLDEEG-GPEARTFHSMAS-DENHVYVFG 144

                        170       180       190
                 ....*....|....*....|....*....|
gi 755542723 221 GLNAD---NIPLSDGWI--HNITTNCWKQL 245
Cdd:PLN02153 145 GVSKGglmKTPERFRTIeaYNIADGKWVQL 174
Kelch_4 pfam13418
Galactose oxidase, central domain;
202-250 1.43e-09

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 53.00  E-value: 1.43e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755542723  202 HRSWHTLTAITDDKLFLFGGLNADNIPLSDGWIHNITTNCWKQLRHLPY 250
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
PLN02193 PLN02193
nitrile-specifier protein
 31-272 1.59e-07

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 52.65  E-value: 1.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  31 CIHG------RLYVFGG--YDDKGYSNRLYFVNLRTRdgtyTWEkITKFDGQPPTprdkLSCwvYKDRLIYFGGYGYrrh 102
Cdd:PLN02193 167 CSHGiaqvgnKIYSFGGefTPNQPIDKHLYVFDLETR----TWS-ISPATGDVPH----LSC--LGVRMVSIGSTLY--- 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 103 selqeCFDVHDASWEeqifwgwHNDVHVFDTKTRTWS--QPEIKGgvpPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLH 180
Cdd:PLN02193 233 -----VFGGRDASRQ-------YNGFYSFDTTTNEWKllTPVEEG---PTPRSFHSMAADEENVYVFGGVSATARLKTLD 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 181 YLNL--DTWVwsgRISVNGESPKHRSWHTLtAITDDKLFLFGGLNADNIplSDGWIHNITTNCWKQLRHL---PYTRpRL 255
Cdd:PLN02193 298 SYNIvdKKWF---HCSTPGDSFSIRGGAGL-EVVQGKVWVVYGFNGCEV--DDVHYYDPVQDKWTQVETFgvrPSER-SV 370

                        250
                 ....*....|....*..
gi 755542723 256 WHTACLGKenEIMVFGG 272
Cdd:PLN02193 371 FASAAVGK--HIVIFGG 385
PLN02193 PLN02193
nitrile-specifier protein
 138-272 4.85e-07

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 51.49  E-value: 4.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 138 WSQPEIKGGvPPQPRAAHSCAVLGNKGYVFGGRVLQTRMND--LHYLNLDTWVWSgrIS-VNGESPKHRSWHTLTAITDD 214
Cdd:PLN02193 153 WIKVEQKGE-GPGLRCSHGIAQVGNKIYSFGGEFTPNQPIDkhLYVFDLETRTWS--ISpATGDVPHLSCLGVRMVSIGS 229

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 755542723 215 KLFLFGGLNADNiPLSDGWIHNITTNCWKQLRHLPY-TRPRLWHTACLGKENeIMVFGG 272
Cdd:PLN02193 230 TLYVFGGRDASR-QYNGFYSFDTTTNEWKLLTPVEEgPTPRSFHSMAADEEN-VYVFGG 286
PLN02153 PLN02153
epithiospecifier protein
 1-221 5.46e-06

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 47.67  E-value: 5.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723   1 MWTYDIDSGLWKMHLMEGElPPSMS--GSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRDgtytWEKITKFDGQP-PT 77
Cdd:PLN02153  52 LYVFDFNTHTWSIAPANGD-VPRISclGVRMVAVGTKLYIFGGRDEKREFSDFYSYDTVKNE----WTFLTKLDEEGgPE 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  78 PRDKLSCWVYKDRLIYFGGYGY-------RRHSELqECFDVHDASWEE-------------------------------Q 119
Cdd:PLN02153 127 ARTFHSMASDENHVYVFGGVSKgglmktpERFRTI-EAYNIADGKWVQlpdpgenfekrggagfavvqgkiwvvygfatS 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 120 IFWGWHND-----VHVFDTKTRTWSQPEIKGGvPPQPRAAHSCAVLGNKGYVFGGRVLQ---------TRMNDLHYLNLD 185
Cdd:PLN02153 206 ILPGGKSDyesnaVQFFDPASGKWTEVETTGA-KPSARSVFAHAVVGKYIIIFGGEVWPdlkghlgpgTLSNEGYALDTE 284

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 755542723 186 TWVWSgRISVNGESPKHRSWHTLTAIT---DDKLFLFGG 221
Cdd:PLN02153 285 TLVWE-KLGECGEPAMPRGWTAYTTATvygKNGLLMHGG 322
PRK14131 PRK14131
N-acetylneuraminate epimerase;
19-169 1.39e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 46.55  E-value: 1.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  19 ELPPSMSGSCGACIHGRLYV-FGGYDDKGYSnrlyfvnLRTRDGTYTWEKITKFDGQPptpRDKLSCWVYKDRLIYFGGY 97
Cdd:PRK14131  24 DLPVPFKNGTGAIDNNTVYVgLGSAGTSWYK-------LDLNAPSKGWTKIAAFPGGP---REQAVAAFIDGKLYVFGGI 93

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755542723  98 GYRRHSElqecfdvhdaswEEQIFwgwhNDVHVFDTKTRTWSQPEIKggvPPQPRAAHSCAVL-GNKGYVFGG 169
Cdd:PRK14131  94 GKTNSEG------------SPQVF----DDVYKYDPKTNSWQKLDTR---SPVGLAGHVAVSLhNGKAYITGG 147
Kelch_3 pfam13415
Galactose oxidase, central domain;
213-261 2.72e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 41.12  E-value: 2.72e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 755542723  213 DDKLFLFGGLNAD-NIPLSDGWIHNITTNCWKQLRHLPytRPRLWHTACL 261
Cdd:pfam13415   1 GDKLYIFGGLGFDgQTRLNDLYVYDLDTNTWTQIGDLP--PPRSGHSATY 48
PHA03098 PHA03098
kelch-like protein; Provisional
 4-117 3.33e-05

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 45.53  E-value: 3.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723   4 YDIDSGLWKMHLMegeLPPSMSGSCGACIHGRLYVFGGY---DDKGYSNRLYFVNLRTrdGTYTWEKITKFdgqpptPRD 80
Cdd:PHA03098 411 FSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGIsyiDNIKVYNIVESYNPVT--NKWTELSSLNF------PRI 479

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 755542723  81 KLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASWE 117
Cdd:PHA03098 480 NASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTNTWT 516
PHA03098 PHA03098
kelch-like protein; Provisional
 125-250 7.47e-05

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 44.37  E-value: 7.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 125 HNDVHVFDTKTRTW-SQPEIKggvppQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWsgRISVNGESPKHR 203
Cdd:PHA03098 310 VNSVVSYDTKTKSWnKVPELI-----YPRKNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKW--REEPPLIFPRYN 382

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 755542723 204 SwhtLTAITDDKLFLFGGLNADNIPLSDGWIHNITTNCWKQLRHLPY 250
Cdd:PHA03098 383 P---CVVNVNNLIYVIGGISKNDELLKTVECFSLNTNKWSKGSPLPI 426
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 151-190 1.33e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 1.33e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 755542723  151 PRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWS 190
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWS 40
PHA03098 PHA03098
kelch-like protein; Provisional
 36-276 4.09e-04

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 42.06  E-value: 4.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723  36 LYVFGGYDDKGYSNRLYF-VNLRTRDgtytWEKITKFDgqppTPRDKLSCWVYKDRLIYFGGYGYRrhselqecfdvhda 114
Cdd:PHA03098 297 IYFIGGMNKNNLSVNSVVsYDTKTKS----WNKVPELI----YPRKNPGVTVFNNRIYVIGGIYNS-------------- 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 115 sweeqifwGWHNDVHVFDTKTRTWSQ-PEIKggvppQPRAAHSCAVLGNKGYVFGGRVL-QTRMNDLHYLNLDTWVWSGR 192
Cdd:PHA03098 355 --------ISLNTVESWKPGESKWREePPLI-----FPRYNPCVVNVNNLIYVIGGISKnDELLKTVECFSLNTNKWSKG 421

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 193 IsvngESPKHRSWHTlTAITDDKLFLFGGLNADNIPLSDGWI--HNITTNCWKQLRhlPYTRPRLWHTACLgKENEIMVF 270
Cdd:PHA03098 422 S----PLPISHYGGC-AIYHDGKIYVIGGISYIDNIKVYNIVesYNPVTNKWTELS--SLNFPRINASLCI-FNNKIYVV 493


                 ....*.
gi 755542723 271 GGSKDN 276
Cdd:PHA03098 494 GGDKYE 499
Kelch_3 pfam13415
Galactose oxidase, central domain;
161-211 6.28e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 37.27  E-value: 6.28e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 755542723  161 GNKGYVFGGRVL--QTRMNDLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAI 211
Cdd:pfam13415   1 GDKLYIFGGLGFdgQTRLNDLYVYDLDTNTW----TQIGDLPPPRSGHSATYI 49
Kelch_6 pfam13964
Kelch motif;
30-79 3.71e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 35.00  E-value: 3.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 755542723   30 ACIHGRLYVFGGYDDKG-YSNRLYFVNLRTRdgtyTWEKItkfdGQPPTPR 79
Cdd:pfam13964   8 VSVGGYIYVFGGYTNASpALNKLEVYNPLTK----SWEEL----PPLPTPR 50
Kelch_6 pfam13964
Kelch motif;
151-190 4.22e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 35.00  E-value: 4.22e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 755542723  151 PRAAHSCAVLGNKGYVFGGRVLQ-TRMNDLHYLNLDTWVWS 190
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNAsPALNKLEVYNPLTKSWE 41
PLN02772 PLN02772
guanylate kinase
 127-200 4.67e-03

guanylate kinase


Pssm-ID: 215414 [Multi-domain]  Cd Length: 398  Bit Score: 38.67  E-value: 4.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755542723 127 DVHVFDTKTRTWSQPEIKgGVPPQPRAAHSCAVLgNKGYVFGGRVLQTRMNDLHYLNLDTW--------------VWSGR 192
Cdd:PLN02772  52 GVQILDKITNNWVSPIVL-GTGPKPCKGYSAVVL-NKDRILVIKKGSAPDDSIWFLEVDTPfvreqkkllgtevvAWSKG 129


                 ....*...
gi 755542723 193 ISVNGESP 200
Cdd:PLN02772 130 VRGNAEKP 137
Kelch_6 pfam13964
Kelch motif;
209-252 5.90e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 34.62  E-value: 5.90e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 755542723  209 TAITDDKLFLFGGLNADNIPLSDGWIHNITTNCWKQLRHLPYTR 252
Cdd:pfam13964   7 VVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_4 pfam13418
Galactose oxidase, central domain;
22-77 7.95e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.12  E-value: 7.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 755542723   22 PSMSGSCGACIHGRLYVFGGYDDKG-YSNRLYFVNLRTRdgtyTWEKItkfdGQPPT 77
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGtLLSDLWVFDLSTN----EWTRL----GSLPS 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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