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Conserved domains on  [gi|568961680|ref|XP_006511327|]
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centrosomal protein of 162 kDa isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
607-734 3.04e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 3.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680 607 EKELLMLKRAQDAEEKWTGAQALMEQMKmTFCEKEKELENTVESLkRQQERELFRLNQENYILQAKLSSFEETSRKQRWL 686
Cdd:COG4717  115 REELEKLEKLLQLLPLYQELEALEAELA-ELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEE 192

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 568961680 687 QFGETSdpltgEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQ 734
Cdd:COG4717  193 ELQDLA-----EELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
607-734 3.04e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 3.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680 607 EKELLMLKRAQDAEEKWTGAQALMEQMKmTFCEKEKELENTVESLkRQQERELFRLNQENYILQAKLSSFEETSRKQRWL 686
Cdd:COG4717  115 REELEKLEKLLQLLPLYQELEALEAELA-ELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEE 192

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 568961680 687 QFGETSdpltgEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQ 734
Cdd:COG4717  193 ELQDLA-----EELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 627-732 1.01e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 41.89  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680  627 QALMEQMKMTFCEKEKElentvESLKRQQERELFRLNQENYILQAKLSSFEETSRK-QRWLQfgETSDPLTGEKLKQIQK 705
Cdd:pfam02841 197 QALTAKEKAIEAERAKA-----EAAEAEQELLREKQKEEEQMMEAQERSYQEHVKQlIEKME--AEREQLLAEQERMLEH 269

                          90       100
                  ....*....|....*....|....*...
gi 568961680  706 EIQEQETLL-QGYQQENERLYNQVKDLQ 732
Cdd:pfam02841 270 KLQEQEELLkEGFKTEAESLQKEIQDLK 297
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 615-757 6.44e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 6.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680   615 RAQDAEEKWTGAQALMEQMKMTFCEKEKELENTVEslkrqqerELFRLNQENYILQAKLSSFEET-SRKQRWLQFGETSD 693
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALAN--------EISRLEQQKQILRERLANLERQlEELEAQLEELESKL 332

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568961680   694 PLTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLN 757
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
607-734 3.04e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 3.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680 607 EKELLMLKRAQDAEEKWTGAQALMEQMKmTFCEKEKELENTVESLkRQQERELFRLNQENYILQAKLSSFEETSRKQRWL 686
Cdd:COG4717  115 REELEKLEKLLQLLPLYQELEALEAELA-ELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEE 192

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 568961680 687 QFGETSdpltgEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQ 734
Cdd:COG4717  193 ELQDLA-----EELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 627-732 1.01e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 41.89  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680  627 QALMEQMKMTFCEKEKElentvESLKRQQERELFRLNQENYILQAKLSSFEETSRK-QRWLQfgETSDPLTGEKLKQIQK 705
Cdd:pfam02841 197 QALTAKEKAIEAERAKA-----EAAEAEQELLREKQKEEEQMMEAQERSYQEHVKQlIEKME--AEREQLLAEQERMLEH 269

                          90       100
                  ....*....|....*....|....*...
gi 568961680  706 EIQEQETLL-QGYQQENERLYNQVKDLQ 732
Cdd:pfam02841 270 KLQEQEELLkEGFKTEAESLQKEIQDLK 297
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 615-757 6.44e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 6.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961680   615 RAQDAEEKWTGAQALMEQMKMTFCEKEKELENTVEslkrqqerELFRLNQENYILQAKLSSFEET-SRKQRWLQFGETSD 693
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALAN--------EISRLEQQKQILRERLANLERQlEELEAQLEELESKL 332

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568961680   694 PLTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLN 757
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396
FtsB COG2919
Cell division protein FtsB [Cell cycle control, cell division, chromosome partitioning];
699-741 7.83e-03

Cell division protein FtsB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442163 [Multi-domain]  Cd Length: 96  Bit Score: 36.40  E-value: 7.83e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 568961680 699 KLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEER 741
Cdd:COG2919   30 AYRELRQEIAELEAENAKLKARNAELEAEVADLKDGPDYIEER 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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