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Conserved domains on  [gi|568923496|ref|XP_006501878.1|]
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PREDICTED: transcription factor SPT20 homolog isoform X9 [Mus musculus]

Protein Classification

Spt20 domain-containing protein (domain architecture ID 10572640)

Spt20 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Spt20 pfam12090
Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. ...
76-216 4.48e-30

Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains.


:

Pssm-ID: 314896  Cd Length: 199  Bit Score: 117.56  E-value: 4.48e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923496   76 LVVNLYPGNEGYslmlrgKNGSDSETIRLPYEE--GELLEYLDAEELPPILVDLLEKSQVnIFHCGCVIAEIRDYRQSS- 152
Cdd:pfam12090  16 LELHIHPNHFRF------KKNNNSDDIIFPYNSemKEFLEYVERGTIPHEMVELLRDFNI-RFYDGCLIVQVIDHRNSPs 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923496  153 -------------------------NMKSPGYQSR-------------HILLRPTMQTLVCDVHSITSDNHKWTQEDKLL 194
Cdd:pfam12090  89 qsqltqqqnqqqqqngkdstttqeqDQKAPSPNNSgtsktpttkpkvyRTLLRPTPLSLYADLLYLTDTPMRFSDEDYLE 168
                         170       180
                  ....*....|....*....|..
gi 568923496  195 LESQLILATAEPLCLDPSVAVA 216
Cdd:pfam12090 169 LESEILLATNPPLCLDPSPNPY 190
 
Name Accession Description Interval E-value
Spt20 pfam12090
Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. ...
76-216 4.48e-30

Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains.


Pssm-ID: 314896  Cd Length: 199  Bit Score: 117.56  E-value: 4.48e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923496   76 LVVNLYPGNEGYslmlrgKNGSDSETIRLPYEE--GELLEYLDAEELPPILVDLLEKSQVnIFHCGCVIAEIRDYRQSS- 152
Cdd:pfam12090  16 LELHIHPNHFRF------KKNNNSDDIIFPYNSemKEFLEYVERGTIPHEMVELLRDFNI-RFYDGCLIVQVIDHRNSPs 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923496  153 -------------------------NMKSPGYQSR-------------HILLRPTMQTLVCDVHSITSDNHKWTQEDKLL 194
Cdd:pfam12090  89 qsqltqqqnqqqqqngkdstttqeqDQKAPSPNNSgtsktpttkpkvyRTLLRPTPLSLYADLLYLTDTPMRFSDEDYLE 168
                         170       180
                  ....*....|....*....|..
gi 568923496  195 LESQLILATAEPLCLDPSVAVA 216
Cdd:pfam12090 169 LESEILLATNPPLCLDPSPNPY 190
 
Name Accession Description Interval E-value
Spt20 pfam12090
Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. ...
76-216 4.48e-30

Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains.


Pssm-ID: 314896  Cd Length: 199  Bit Score: 117.56  E-value: 4.48e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923496   76 LVVNLYPGNEGYslmlrgKNGSDSETIRLPYEE--GELLEYLDAEELPPILVDLLEKSQVnIFHCGCVIAEIRDYRQSS- 152
Cdd:pfam12090  16 LELHIHPNHFRF------KKNNNSDDIIFPYNSemKEFLEYVERGTIPHEMVELLRDFNI-RFYDGCLIVQVIDHRNSPs 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923496  153 -------------------------NMKSPGYQSR-------------HILLRPTMQTLVCDVHSITSDNHKWTQEDKLL 194
Cdd:pfam12090  89 qsqltqqqnqqqqqngkdstttqeqDQKAPSPNNSgtsktpttkpkvyRTLLRPTPLSLYADLLYLTDTPMRFSDEDYLE 168
                         170       180
                  ....*....|....*....|..
gi 568923496  195 LESQLILATAEPLCLDPSVAVA 216
Cdd:pfam12090 169 LESEILLATNPPLCLDPSPNPY 190
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.17
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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