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Conserved domains on  [gi|564396735|ref|XP_006256037|]
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1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
66-252 3.72e-58

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


:

Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 184.01  E-value: 3.72e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  66 LRLLLlhvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFID 145
Cdd:cd07989    1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGR 225
Cdd:cd07989   77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR 155
                        170       180
                 ....*....|....*....|....*....
gi 564396735 226 CQVRVLPPVPTEGL--TPDDVPALADRVR 252
Cdd:cd07989  156 VTVRIGEPIPPEGLelAEEDRKELREKVR 184
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
66-252 3.72e-58

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 184.01  E-value: 3.72e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  66 LRLLLlhvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFID 145
Cdd:cd07989    1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGR 225
Cdd:cd07989   77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR 155
                        170       180
                 ....*....|....*....|....*....
gi 564396735 226 CQVRVLPPVPTEGL--TPDDVPALADRVR 252
Cdd:cd07989  156 VTVRIGEPIPPEGLelAEEDRKELREKVR 184
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
80-208 6.45e-44

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 145.50  E-value: 6.45e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735   80 RVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVM 156
Cdd:pfam01553   1 RIEVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTL 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 564396735  157 SEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:pfam01553  81 EYLVE-LLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
78-208 2.98e-41

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 138.63  E-value: 2.98e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735   78 GIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTgDAISVMS 157
Cdd:TIGR00530   1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENI-RAIATAL 79
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564396735  158 EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:TIGR00530  80 KAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism];
41-265 6.86e-41

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism];


Pssm-ID: 223282 [Multi-domain]  Cd Length: 255  Bit Score: 141.97  E-value: 6.86e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  41 WILFLAILAIPVCAVRGRNVENM--KILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDR- 117
Cdd:COG0204   10 VILFLLLPLPLALIALFRLRRPVlrRWLRFLVLLLLLLFGLRVEVEGLENLPKGGPALVVANHQSFLDPLLLSLALPRRg 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 118 -CVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAisVMSEVAQTLLTQDVRVWVFPEGTR-NHNGSMLPFKRGAFHLA 195
Cdd:COG0204   90 pVRFVAKKELFKVPLLGWLLRLLGAIPVDRENPDDE--TLRAAVARLKAGGRSLVIFPEGTRsRGGEELLPFKRGAARLA 167
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 196 VQAQVPIVPIVMSSYQDFYckkeRRFTSGRCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTIFREISTD 265
Cdd:COG0204  168 LEAGVPIVPVAIVGAEELF----PSLKKGKVKVRIGPPIDISALPEPLLPELAEAVEQLARPILLELLPR 233
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
95-208 5.58e-36

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 124.77  E-value: 5.58e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735    95 YVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQtLLTQDVRVW 171
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVE-LLKEGEWLL 79
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 564396735   172 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
31-255 1.79e-28

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 109.33  E-value: 1.79e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  31 YFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGM 110
Cdd:PRK15018   3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 111 MEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG 190
Cdd:PRK15018  83 SNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTG 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564396735 191 AFHLAVQAQVPIVPIVMSSYQDFYckKERRFTSGRCQVRVLPPVPTEGLTPDDVPALADRVRHSM 255
Cdd:PRK15018 163 AFHAAIAAGVPIIPVCVSTTSNKI--NLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
66-252 3.72e-58

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 184.01  E-value: 3.72e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  66 LRLLLlhvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFID 145
Cdd:cd07989    1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGR 225
Cdd:cd07989   77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR 155
                        170       180
                 ....*....|....*....|....*....
gi 564396735 226 CQVRVLPPVPTEGL--TPDDVPALADRVR 252
Cdd:cd07989  156 VTVRIGEPIPPEGLelAEEDRKELREKVR 184
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
80-208 6.45e-44

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 145.50  E-value: 6.45e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735   80 RVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVM 156
Cdd:pfam01553   1 RIEVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTL 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 564396735  157 SEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:pfam01553  81 EYLVE-LLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
78-208 2.98e-41

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 138.63  E-value: 2.98e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735   78 GIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTgDAISVMS 157
Cdd:TIGR00530   1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENI-RAIATAL 79
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564396735  158 EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:TIGR00530  80 KAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism];
41-265 6.86e-41

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism];


Pssm-ID: 223282 [Multi-domain]  Cd Length: 255  Bit Score: 141.97  E-value: 6.86e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  41 WILFLAILAIPVCAVRGRNVENM--KILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDR- 117
Cdd:COG0204   10 VILFLLLPLPLALIALFRLRRPVlrRWLRFLVLLLLLLFGLRVEVEGLENLPKGGPALVVANHQSFLDPLLLSLALPRRg 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 118 -CVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAisVMSEVAQTLLTQDVRVWVFPEGTR-NHNGSMLPFKRGAFHLA 195
Cdd:COG0204   90 pVRFVAKKELFKVPLLGWLLRLLGAIPVDRENPDDE--TLRAAVARLKAGGRSLVIFPEGTRsRGGEELLPFKRGAARLA 167
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 196 VQAQVPIVPIVMSSYQDFYckkeRRFTSGRCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTIFREISTD 265
Cdd:COG0204  168 LEAGVPIVPVAIVGAEELF----PSLKKGKVKVRIGPPIDISALPEPLLPELAEAVEQLARPILLELLPR 233
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
95-208 5.58e-36

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 124.77  E-value: 5.58e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735    95 YVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQtLLTQDVRVW 171
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVE-LLKEGEWLL 79
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 564396735   172 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
31-255 1.79e-28

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 109.33  E-value: 1.79e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  31 YFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGM 110
Cdd:PRK15018   3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 111 MEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG 190
Cdd:PRK15018  83 SNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTG 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564396735 191 AFHLAVQAQVPIVPIVMSSYQDFYckKERRFTSGRCQVRVLPPVPTEGLTPDDVPALADRVRHSM 255
Cdd:PRK15018 163 AFHAAIAAGVPIIPVCVSTTSNKI--NLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
67-208 6.19e-20

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 84.77  E-value: 6.19e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  67 RLLLLHvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLgMMEVLPDRcvpIAKRELLWAGSA--GLACWL---AGV 141
Cdd:cd06551    2 RYLLLN--FFGFVRLEVKGPPPPPGGGPVLFVSNHSSWWDGL-ILFLLLER---GLRRDVYGLMDEelLERYPFftrLGA 75
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564396735 142 IFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGS-MLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:cd06551   76 FSVDRDSPRSAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVALR 143
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
80-252 1.20e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 79.39  E-value: 1.20e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  80 RVEVRGAQHFP-PTQPYVVVSNHQSSLDLLGMMEVlpDRCVP-IAKRELLWAGSAGLACWLAGVIFIdrKRTgDAISVMS 157
Cdd:PLN02901  36 KIEVEGLENLPsPDEPAVYVSNHQSFLDIYTLFHL--GRPFKfISKTSIFLIPIIGWAMYMTGHIPL--KRM-DRRSQLE 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 158 EVAQT--LLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIV-MSSYQDFYCKKERRFTSGRCQVRVLPPV 234
Cdd:PLN02901 111 CLKRCmeLLKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITlVGTGKIMPNGKEGILNPGSVKVVIHPPI 190
                        170
                 ....*....|....*...
gi 564396735 235 ptEGLTPDDvpaLADRVR 252
Cdd:PLN02901 191 --EGSDADE---LCNEAR 203
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
78-255 8.50e-15

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 71.48  E-value: 8.50e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  78 GIRVEVRGAQHfPPTQPYVVVSNHQSSLDLLGMMEVLPdrCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMS 157
Cdd:cd07991   10 FYVIKVHGKPD-PPEAPRIIVANHTSFIDPLILFSDLF--PSIVAKKELGKLPFIGTILRALGCIFVDRSEPKDRKKVVE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 158 EVAQTLLTQDVR-VWVFPEGTRNHNGSMLPFKRGAFhlavQAQVPIVPIVM----------------SSYQDFYckkeRR 220
Cdd:cd07991   87 EIKERATDPNWPpILIFPEGTTTNGKALIMFKKGAF----EPGVPVQPVAIrypnkfvdafwnssgySSLMYLF----RL 158
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 564396735 221 FTS--GRCQVRVLPPV--PTEGLTPDdvpALADRVRHSM 255
Cdd:cd07991  159 LTQpaNVLEVEFLPVYtpSEEGEDPK---EFANRVRLIM 194
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
75-178 9.43e-13

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 65.34  E-value: 9.43e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  75 YLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLD-LLGMMEVLPDRCVP----IAKRELLWAGSAGLACWLAGVIFIDRKRT 149
Cdd:cd07990    6 WLSGVKVVVYGDEPKLPKERALIISNHRSEVDwLVLWMLADRFGRLGrlkiVLKDSLKYPPLGGWGWQLGEFIFLKRKWE 85
                         90       100       110
                 ....*....|....*....|....*....|.
gi 564396735 150 GDAIsVMSEVAQTLLTQDVRVWV--FPEGTR 178
Cdd:cd07990   86 KDEK-TIKRQLKRLKDSPEPFWLliFPEGTR 115
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
66-257 4.81e-10

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 58.04  E-value: 4.81e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  66 LRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSL-DLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFI 144
Cdd:cd07992    1 VRLLSRVILRIYFRRITVVGRENVPKDGPVIFLGNHPNALiDPLLLAATLRRPVRFLAKADLFKNPLIGWLLESFGAIPV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 145 DRKR----TGDAIS----VMSEVAQTLLTQDvRVWVFPEGTrNHNGS-MLPFKRGAFHLAVQA------QVPIVPIVMss 209
Cdd:cd07992   81 YRPKdlarGGIGKIsnaaVFDAVGEALKAGG-AIGIFPEGG-SHDRPrLLPLKAGAARMALEAleagqkDVKIVPVGL-- 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 564396735 210 yqdFYCKKErRFTSgRCQVRVLPPVPTEGLTPDDVPALADRVRHSMLT 257
Cdd:cd07992  157 ---NYEDKS-RFRS-RVLVEFGKPISVSAFEEAEASRDVEKKLINQLE 199
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
42-204 2.37e-09

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 58.01  E-value: 2.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735   42 ILFLAILAIPVCAVRGRNVEN--MKILRLLLLHVKYlygiRVEVRGAQHFPPTQPYVVVSNHQSSLD--LLGMMEVLPDR 117
Cdd:PRK08633  392 FYLIALVTLIGTLYTLLLLPDslLRFLLLLLMHTRY----RLRVEGRENIPAKGGALLLGNHVSWIDwaLLQAASPRPIR 467
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  118 CV---PIAKRELLwagsaglaCWLA---GVIFIDRKRTGDAISVMSEvaqtLLTQDVRVWVFPEGTRNHNGSMLPFKRGa 191
Cdd:PRK08633  468 FVmerSIYEKWYL--------KWFFklfGVIPISSGGSKESLEFIRK----ALDDGEVVCIFPEGAITRNGQLNEFKRG- 534
                         170
                  ....*....|....
gi 564396735  192 FHLAVQ-AQVPIVP 204
Cdd:PRK08633  535 FELIVKgTDVPIIP 548
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
90-252 1.40e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 49.91  E-value: 1.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  90 PPTQP-YVV-VSNHQSSLDLLGMMEVLPDRCVPI---AKRELLWAGSAGLACWLaGVIFIDRKRTGDAISVMSEVAQTll 164
Cdd:cd07988   16 PPNKPkFVViGAPHTSNWDFVLGLLAAFALGLKIsflGKHSLFKPPLGPFMRWL-GGIPVDRSRAGGLVEQVVEEFRR-- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 165 tQDVRVWVF-PEGTRNHNGsmlPFKRGAFHLAVQAQVPIVPivmsSYQDFYCKkerrftsgrcQVRVLPPVPTEGLTPDD 243
Cdd:cd07988   93 -REEFVLAIaPEGTRSKVD---KWKTGFYHIARGAGVPILL----VYLDYKRK----------TVGIGPLFEPSGDIEAD 154

                 ....*....
gi 564396735 244 VPALADRVR 252
Cdd:cd07988  155 LAAIRAFYR 163
LPLAT_DHAPAT-like cd07993
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ...
139-229 3.79e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.


Pssm-ID: 153255 [Multi-domain]  Cd Length: 205  Bit Score: 49.49  E-value: 3.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 139 AGVIFIDRKRTGDAI--SVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG-------AFHLAVQAQVPIVPIVMsS 209
Cdd:cd07993   71 LGAFFIRRSFGKDPLyrAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGllsvvveAYLKGSVPDVLIVPVSI-S 149
                         90       100       110
                 ....*....|....*....|....*....|.
gi 564396735 210 Y-----QDFYC------KKERRFTSGRCQVR 229
Cdd:cd07993  150 YdrvleEELYAeellgpPKPKESLSGLLGAS 180
PRK14014 PRK14014
putative acyltransferase; Provisional
74-146 4.42e-07

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 50.24  E-value: 4.42e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564396735  74 KYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRcVPI----AKRELLWAGSAGLACWLAGVIFIDR 146
Cdd:PRK14014  68 RLLPRTQWDVEGLEGLSKKGWYLVISNHQSWVDILVLQYVFNRR-IPMlkffLKQELIWVPFLGLAWWALDFPFMKR 143
PRK06814 PRK06814
acyl-[ACP]--phospholipid O-acyltransferase;
33-254 3.65e-06

acyl-[ACP]--phospholipid O-acyltransferase;


Pssm-ID: 235865 [Multi-domain]  Cd Length: 1140  Bit Score: 48.04  E-value: 3.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735   33 FKMAFYNGWILFL-----AILAIPVCAVRGRNVenMK-ILRLLLlhvKYLYgiRVEVRGAQHFPPTQP-YVVVSNHQSSL 105
Cdd:PRK06814  394 QALGFSIPWIILFialanLIVAILILRLLPTNL--LRdIFSILF---RAFY--RVEVKGLENLQKAGKkAVIAANHVSFL 466
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  106 DLLGMMEVLPDRCV-----PIAKRellWagsaglacWLAGVIFIDRKRTGDAISVMSevAQTL---LTQDVRVWVFPEGT 177
Cdd:PRK06814  467 DGPLLAAYLPEEPTfaidtDIAKA---W--------WVKPFLKLAKALPVDPTNPMA--TRTLikeVQKGEKLVIFPEGR 533
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  178 RNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYC----KKERRFTSGRCQVRVLPPVpteglTPDDVPALADRVRH 253
Cdd:PRK06814  534 ITVTGSLMKIYDGPGMIADKAGAMVVPVRIDGLQFTHFsrlkNQVRRKWFPKVTVTILPPV-----KLAVDPELKGRERR 608

                  .
gi 564396735  254 S 254
Cdd:PRK06814  609 S 609
LPLAT_ACT14924-like cd07986
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
79-205 4.34e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Pectobacterium carotovorum subsp. carotovorum PC1 locus ACT14924 putative acyltransferase, and similar proteins.


Pssm-ID: 153248 [Multi-domain]  Cd Length: 210  Bit Score: 46.47  E-value: 4.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  79 IRVEVRGAQHFPPTQPYVVVSNHQ-SSLDLLGMMEVL----PDrcVPIAKRELLWAGSAgLACWLAGVIFIDRKRTGD-A 152
Cdd:cd07986    8 LEVDVSGLENIPKDGPVVIVANHPfGILDGLILADLLgsvrPD--VRILANQLLSKIPE-LRDLFIPVDPLEGRAALAkN 84
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564396735 153 ISVMSEvAQTLLTQDVRVWVFPEGT-----RNHNGSM-LPFKRGAFHLAVQAQVPIVPI 205
Cdd:cd07986   85 RESLRE-ALRHLKNGGALIIFPAGRvstasPPFGRVSdRPWNPFVARLARKAKAPVVPV 142
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
82-204 2.61e-04

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 41.12  E-value: 2.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  82 EVRGAQHFPPTQPYVVVSNHqssldllGMMevLPDRCVPIAKRELLWAGsagLACWLAGVIFI-------DRKRTGDAIS 154
Cdd:cd07987    9 EVRGLENIPDEGPALLVHPH-------GGL--PIDGALLAAAFLLLFPG---RLPRALADHFLfplpglrDLLRRLGAVP 76
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564396735 155 VMSEVAQTLLTQDVRVWVFPEGTR-------NHNGSMLPFKRGAFHLAVQAQVPIVP 204
Cdd:cd07987   77 GSRENCVRLLREGELVLIFPGGARealkskrEEYYLLWKKRKGFARLALRAGAPIVP 133
PlsB COG2937
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism];
94-198 2.43e-03

Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism];


Pssm-ID: 225488 [Multi-domain]  Cd Length: 810  Bit Score: 39.32  E-value: 2.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  94 PYVVVSNHQSSLDLLGMMEVLPD-RCVPIakrelLWAGSAGLACWLAG-------VIFIDRKRTGDAI--SVMSEVAQTL 163
Cdd:COG2937  297 EIVYVPCHRSHIDYLLLSYVLYHnGLVPP-----HIAAGINLNFWPMGpifrrggAFFIRRTFKGNPLysTVFREYLGEL 371
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 564396735 164 LTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQA 198
Cdd:COG2937  372 FSRGYSLEYFIEGGRSRTGRLLPPKTGMLSMTLQA 406
PLN02833 PLN02833
glycerol acyltransferase family protein
22-252 4.72e-03

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 37.83  E-value: 4.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  22 LWFCSSSAKYF--FKMAF---YNGWILFLAiLAIPVCAVRGRNVENMKILRLLLLH------------VKYlYGIRVEVR 84
Cdd:PLN02833  85 LWCVGVVIRYGilFPVRVlllAIGWIIFLS-AFIPVHFLLKGHKLRKKIERKLVELicsafvaswtgvIKY-HGPRPSRR 162
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735  85 GAQhfpptqpyVVVSNHQSSLDLLGMMEVLPdrCVPIAKRELLWAG---SAGLACwlAGVIFIDRKRTGDaisvmSEVAQ 161
Cdd:PLN02833 163 PKQ--------VFVANHTSMIDFIVLEQMTP--FAVIMQKHPGWVGflqNTILES--VGCIWFNRTEAKD-----REVVA 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564396735 162 TLLTQDVR------VWVFPEGTRNHNGSMLPFKRGAFHLAVQaqvpIVPIVM------------SSYQDFYCKKERRFTS 223
Cdd:PLN02833 226 KKLRDHVQdpdrnpLLIFPEGTCVNNEYTVMFKKGAFELGCT----VCPIAIkynkifvdafwnSRKQSFTMHLLRLMTS 301
                        250       260       270
                 ....*....|....*....|....*....|..
gi 564396735 224 GR--CQVRVLPPvptEGLTPDDVP-ALADRVR 252
Cdd:PLN02833 302 WAvvCDVWYLEP---QTLRPGETPiEFAERVR 330
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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