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Conserved domains on  [gi|290491128|ref|NP_443749|]
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PALM2-AKAP2 fusion protein isoform 1 (PALM2) [Homo sapiens]

Protein Classification

Paralemmin domain-containing protein( domain architecture ID 10505538)

Paralemmin domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Paralemmin pfam03285
Paralemmin;
15-368 8.72e-124

Paralemmin;


:

Pssm-ID: 460875  Cd Length: 301  Bit Score: 360.21  E-value: 8.72e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   15 AEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTL 94
Cdd:pfam03285   1 AEKRKRQTEIENKRRQLEDDRRQLQHLKSKALRERWLLEGPPSSASEEDEARRRQEEEDEQKKKLLEEIIRRLEEEIELL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   95 ESEESQISAKEQIILEKLketeksfkdfqkgfsstdgdavnyissqlpdlpilcsrtaepspgqdgtsraaavyamEINV 174
Cdd:pfam03285  81 EEESSISAKKENLAEKLL----------------------------------------------------------EITV 102

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  175 EKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHV---S 251
Cdd:pfam03285 103 EKDKVTGETRVLSSTTLLPDDVQPQGVKVYDDETKVVHEVSGGDGTEENGVHPLSSSEVEELIHKADEVTLGEGGStaaP 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  252 ERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPSAAGP--EANLDQPVTMIFMGYQNIEDEEETKKV 329
Cdd:pfam03285 183 EVRGTADGGDVSPKEEMTPKRAKLEMVHKPRKDHEITGVEAQPGETTSEPPgaAASAEPPVTMIFMGYQNVEDEEETKKV 262

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 290491128  330 LGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAE 368
Cdd:pfam03285 263 LGLETTIKAELVVIEDDEEKLREKTVTDDSTIPNGAAAE 301
 
Name Accession Description Interval E-value
Paralemmin pfam03285
Paralemmin;
15-368 8.72e-124

Paralemmin;


Pssm-ID: 460875  Cd Length: 301  Bit Score: 360.21  E-value: 8.72e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   15 AEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTL 94
Cdd:pfam03285   1 AEKRKRQTEIENKRRQLEDDRRQLQHLKSKALRERWLLEGPPSSASEEDEARRRQEEEDEQKKKLLEEIIRRLEEEIELL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   95 ESEESQISAKEQIILEKLketeksfkdfqkgfsstdgdavnyissqlpdlpilcsrtaepspgqdgtsraaavyamEINV 174
Cdd:pfam03285  81 EEESSISAKKENLAEKLL----------------------------------------------------------EITV 102

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  175 EKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHV---S 251
Cdd:pfam03285 103 EKDKVTGETRVLSSTTLLPDDVQPQGVKVYDDETKVVHEVSGGDGTEENGVHPLSSSEVEELIHKADEVTLGEGGStaaP 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  252 ERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPSAAGP--EANLDQPVTMIFMGYQNIEDEEETKKV 329
Cdd:pfam03285 183 EVRGTADGGDVSPKEEMTPKRAKLEMVHKPRKDHEITGVEAQPGETTSEPPgaAASAEPPVTMIFMGYQNVEDEEETKKV 262

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 290491128  330 LGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAE 368
Cdd:pfam03285 263 LGLETTIKAELVVIEDDEEKLREKTVTDDSTIPNGAAAE 301
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-124 5.77e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 5.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   4 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKwllqgipAGTAEEEEARRRQSEedefRVKQLEDN 83
Cdd:COG1196  249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL-------AELARLEQDIARLEE----RRRELEER 317

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 290491128  84 IQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:COG1196  318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-124 2.68e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 2.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128     2 AEAELHkERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLE 81
Cdd:TIGR02168  237 LREELE-ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 290491128    82 DNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358
PRK12704 PRK12704
phosphodiesterase; Provisional
 17-124 2.82e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 39.76  E-value: 2.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  17 KRKRQTEIEGKRQQLdEQILLLQHSKSKVLREKWLLQgipagtAEEEEARRRQSEEDEFRVK--QLEDNIQRLEQEIQTL 94
Cdd:PRK12704  26 KKIAEAKIKEAEEEA-KRILEEAKKEAEAIKKEALLE------AKEEIHKLRNEFEKELRERrnELQKLEKRLLQKEENL 98

                         90       100       110
                 ....*....|....*....|....*....|
gi 290491128  95 ESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:PRK12704  99 DRKLELLEKREEELEKKEKELEQKQQELEK 128
 
Name Accession Description Interval E-value
Paralemmin pfam03285
Paralemmin;
15-368 8.72e-124

Paralemmin;


Pssm-ID: 460875  Cd Length: 301  Bit Score: 360.21  E-value: 8.72e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   15 AEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTL 94
Cdd:pfam03285   1 AEKRKRQTEIENKRRQLEDDRRQLQHLKSKALRERWLLEGPPSSASEEDEARRRQEEEDEQKKKLLEEIIRRLEEEIELL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   95 ESEESQISAKEQIILEKLketeksfkdfqkgfsstdgdavnyissqlpdlpilcsrtaepspgqdgtsraaavyamEINV 174
Cdd:pfam03285  81 EEESSISAKKENLAEKLL----------------------------------------------------------EITV 102

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  175 EKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHV---S 251
Cdd:pfam03285 103 EKDKVTGETRVLSSTTLLPDDVQPQGVKVYDDETKVVHEVSGGDGTEENGVHPLSSSEVEELIHKADEVTLGEGGStaaP 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  252 ERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPSAAGP--EANLDQPVTMIFMGYQNIEDEEETKKV 329
Cdd:pfam03285 183 EVRGTADGGDVSPKEEMTPKRAKLEMVHKPRKDHEITGVEAQPGETTSEPPgaAASAEPPVTMIFMGYQNVEDEEETKKV 262

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 290491128  330 LGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAE 368
Cdd:pfam03285 263 LGLETTIKAELVVIEDDEEKLREKTVTDDSTIPNGAAAE 301
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-124 5.77e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 5.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   4 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKwllqgipAGTAEEEEARRRQSEedefRVKQLEDN 83
Cdd:COG1196  249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL-------AELARLEQDIARLEE----RRRELEER 317

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 290491128  84 IQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:COG1196  318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
8-114 1.66e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128    8 KERLQA-IAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEF----RVKQLED 82
Cdd:COG4913   340 LEQLEReIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAeaeaALRDLRR 419

                          90       100       110
                  ....*....|....*....|....*....|..
gi 290491128   83 NIQRLEQEIQTLESEESQISAKEQIILEKLKE 114
Cdd:COG4913   420 ELRELEAEIASLERRKSNIPARLLALRDALAE 451
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
9-117 1.27e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   9 ERLQAIAEKRKRQTEIEGKRQQLDEQILLLqhsksKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLE 88
Cdd:COG4717  385 EELRAALEQAEEYQELKEELEELEEQLEEL-----LGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELE 459

                         90       100       110
                 ....*....|....*....|....*....|.
gi 290491128  89 QEIQTLESEE--SQISAKEQIILEKLKETEK 117
Cdd:COG4717  460 AELEQLEEDGelAELLQELEELKAELRELAE 490
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3-123 1.87e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 1.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128    3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQillLQHSKSKVLREKWLLQGIPA-----GTAEEEEARRRQSEEDEFRV 77
Cdd:pfam17380 469 EEERKRKKLELEKEKRDRKRAEEQRRKILEKE---LEERKQAMIEEERKRKLLEKemeerQKAIYEEERRREAEEERRKQ 545

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 290491128   78 KQLEDNiQRLEQEIQTLESEESQISA--KEQIILEKLKETEKSFKDFQ 123
Cdd:pfam17380 546 QEMEER-RRIQEQMRKATEERSRLEAmeREREMMRQIVESEKARAEYE 592
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1-124 1.92e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQL 80
Cdd:COG4717  118 LEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL 197

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 290491128  81 EDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:COG4717  198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL 241
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-124 2.25e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 2.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEAR----------RRQSE 71
Cdd:COG1196  317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELeelaeelleaLRAAA 396

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 290491128  72 EDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:COG1196  397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 5-104 2.48e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   5 ELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNI 84
Cdd:COG4942  143 YLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEA 222

                         90       100
                 ....*....|....*....|
gi 290491128  85 QRLEQEIQTLESEESQISAK 104
Cdd:COG4942  223 EELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
4-141 4.34e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128    4 AELHKERLQA---IAEKRKRQTEIEGKRQQLDEQILLLQhsksKVLREKWLLQGIPAgtAEEE----EARRRQSEEDEFR 76
Cdd:COG4913   613 AALEAELAELeeeLAEAEERLEALEAELDALQERREALQ----RLAEYSWDEIDVAS--AEREiaelEAELERLDASSDD 686

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 290491128   77 VKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQL 141
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-95 1.02e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLE 81
Cdd:COG1196  687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766

                         90
                 ....*....|....
gi 290491128  82 DNIQRLEQEIQTLE 95
Cdd:COG1196  767 RELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-124 2.65e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.92  E-value: 2.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   2 AEAELHKERLQaIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKwllqgipAGTAEEEEARRRQSEEDEFRVKQLE 81
Cdd:COG1196  272 LRLELEELELE-LEEAQAEEYELLAELARLEQDIARLEERRRELEERL-------EELEEELAELEEELEELEEELEELE 343

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 290491128  82 DNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:COG1196  344 EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-124 2.68e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 2.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128     2 AEAELHkERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLE 81
Cdd:TIGR02168  237 LREELE-ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 290491128    82 DNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358
PRK12704 PRK12704
phosphodiesterase; Provisional
 17-124 2.82e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 39.76  E-value: 2.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128  17 KRKRQTEIEGKRQQLdEQILLLQHSKSKVLREKWLLQgipagtAEEEEARRRQSEEDEFRVK--QLEDNIQRLEQEIQTL 94
Cdd:PRK12704  26 KKIAEAKIKEAEEEA-KRILEEAKKEAEAIKKEALLE------AKEEIHKLRNEFEKELRERrnELQKLEKRLLQKEENL 98

                         90       100       110
                 ....*....|....*....|....*....|
gi 290491128  95 ESEESQISAKEQIILEKLKETEKSFKDFQK 124
Cdd:PRK12704  99 DRKLELLEKREEELEKKEKELEQKQQELEK 128
ARGLU pfam15346
Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ...
 1-111 3.14e-03

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.


Pssm-ID: 405931 [Multi-domain]  Cd Length: 151  Bit Score: 38.11  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128    1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEqiLLLQHSKskvlrekwllqgipagtaEEEEARRRQSEEdefRVKQL 80
Cdd:pfam15346  53 QVLEELEREREAELEEERRKEEEERKKREELER--ILEENNR------------------KIEEAQRKEAEE---RLAML 109

                          90       100       110
                  ....*....|....*....|....*....|..
gi 290491128   81 EDnIQRLEQEIQTLESEESQISAKEQ-IILEK 111
Cdd:pfam15346 110 EE-QRRMKEERQRREKEEEEREKREQqKILNK 140
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 4-132 3.39e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 39.49  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128    4 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQI-----------LLLQHSKSKV--LREKWL-LQGIPAGTAEEEEARRRQ 69
Cdd:pfam07888  44 AELLQAQEAANRQREKEKERYKRDREQWERQRrelesrvaelkEELRQSREKHeeLEEKYKeLSASSEELSEEKDALLAQ 123

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 290491128   70 SEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGD 132
Cdd:pfam07888 124 RAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEE 186
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
8-128 6.75e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.60  E-value: 6.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   8 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIpagtAEEEEARRRQSEEDEfRVKQLEDNIQRL 87
Cdd:COG4717   84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY----QELEALEAELAELPE-RLEELEERLEEL 158

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 290491128  88 EQEIQTLESEESQISAKEQIILEKLK----ETEKSFKDFQKGFSS 128
Cdd:COG4717  159 RELEEELEELEAELAELQEELEELLEqlslATEEELQDLAEELEE 203
mukB PRK04863
chromosome partition protein MukB;
12-106 9.12e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 38.40  E-value: 9.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290491128   12 QAIAEKRKRQTEIEGKRQQLDEQILLlQHSKSKVLREKWLL--QGIP----------AGTAEEEEARRRQSEEDEFRVKQ 79
Cdd:PRK04863  837 AELRQLNRRRVELERALADHESQEQQ-QRSQLEQAKEGLSAlnRLLPrlnlladetlADRVEEIREQLDEAEEAKRFVQQ 915

                          90       100
                  ....*....|....*....|....*..
gi 290491128   80 LEDNIQRLEQEIQTLESEESQISAKEQ 106
Cdd:PRK04863  916 HGNALAQLEPIVSVLQSDPEQFEQLKQ 942
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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