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Conserved domains on  [gi|45269152|ref|NP_032398.3|]
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interleukin-7 receptor subunit alpha precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
fn3 pfam00041
Fibronectin type III domain;
131-219 2.46e-05

Fibronectin type III domain;


:

Pssm-ID: 306538  Cd Length: 85  Bit Score: 43.56  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45269152   131 APSDLKVVYRKEaNDFLVTFNAPHLKKKYLKKvkHDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIph 210
Cdd:pfam00041   2 APSNLTVTDVTS-TSLTVSWTPPPDGNGPITG--YEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV-- 76

                  ....*....
gi 45269152   211 NDYFKGFWS 219
Cdd:pfam00041  77 NGGGEGPPS 85
 
Name Accession Description Interval E-value
fn3 pfam00041
Fibronectin type III domain;
131-219 2.46e-05

Fibronectin type III domain;


Pssm-ID: 306538  Cd Length: 85  Bit Score: 43.56  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45269152   131 APSDLKVVYRKEaNDFLVTFNAPHLKKKYLKKvkHDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIph 210
Cdd:pfam00041   2 APSNLTVTDVTS-TSLTVSWTPPPDGNGPITG--YEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV-- 76

                  ....*....
gi 45269152   211 NDYFKGFWS 219
Cdd:pfam00041  77 NGGGEGPPS 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
130-229 7.60e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020  Cd Length: 93  Bit Score: 35.94  E-value: 7.60e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45269152 130 EAPSDLKVVYRkEANDFLVTFNAPHLKKKYLKKVKhdVAYRPArGESNWTHVSL-FHTRTTIPQRKLRPKAMYEIKVRSi 208
Cdd:cd00063   2 SPPTNLRVTDV-TSTSVTLSWTPPEDDGGPITGYV--VEYREK-GSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRA- 76
                        90       100
                ....*....|....*....|.
gi 45269152 209 phndYFKGFWSEWSPSSTFET 229
Cdd:cd00063  77 ----VNGGGESPPSESVTVTT 93
 
Name Accession Description Interval E-value
fn3 pfam00041
Fibronectin type III domain;
131-219 2.46e-05

Fibronectin type III domain;


Pssm-ID: 306538  Cd Length: 85  Bit Score: 43.56  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45269152   131 APSDLKVVYRKEaNDFLVTFNAPHLKKKYLKKvkHDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIph 210
Cdd:pfam00041   2 APSNLTVTDVTS-TSLTVSWTPPPDGNGPITG--YEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV-- 76

                  ....*....
gi 45269152   211 NDYFKGFWS 219
Cdd:pfam00041  77 NGGGEGPPS 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
130-229 7.60e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020  Cd Length: 93  Bit Score: 35.94  E-value: 7.60e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45269152 130 EAPSDLKVVYRkEANDFLVTFNAPHLKKKYLKKVKhdVAYRPArGESNWTHVSL-FHTRTTIPQRKLRPKAMYEIKVRSi 208
Cdd:cd00063   2 SPPTNLRVTDV-TSTSVTLSWTPPEDDGGPITGYV--VEYREK-GSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRA- 76
                        90       100
                ....*....|....*....|.
gi 45269152 209 phndYFKGFWSEWSPSSTFET 229
Cdd:cd00063  77 ----VNGGGESPPSESVTVTT 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.16
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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