NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|37622349|ref|NP_006622|]
View 

zinc finger protein 266 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
210-549 4.66e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 4.66e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 210 KPYKCKECGKGFRYSAYLNIHMGTHTGDNPYEC--KECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQ-H 286
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlS 111
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 287 MKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPykckdCGKAFTQNSD 366
Cdd:COG5048 112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 367 LTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTgEKPFECVKCGKAFAISSNLSGHLRIHTGEKPFECLEC----- 441
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESprssl 265
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 442 GKAFTHSSSLNNH-MRTHSAK-KPFTCMECGKAFKFPTCVNLHMR--IHTGE--KPYKC--KQCGKSFSYSNSFQLHERT 513
Cdd:COG5048 266 PTASSQSSSPNESdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345
                       330       340       350
                ....*....|....*....|....*....|....*...
gi 37622349 514 HTGEKPYECK--ECGKAFSSSSSFRNHERRHADERLSA 549
Cdd:COG5048 346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKN 383
KRAB super family cl42959
krueppel associated box;
1-28 5.82e-08

krueppel associated box;


The actual alignment was detected with superfamily member smart00349:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 49.51  E-value: 5.82e-08
                           10        20
                   ....*....|....*....|....*...
gi 37622349      1 MLENYKNLATVGYQLFKPSLISWLEQEE 28
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGE 57
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
210-549 4.66e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 4.66e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 210 KPYKCKECGKGFRYSAYLNIHMGTHTGDNPYEC--KECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQ-H 286
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlS 111
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 287 MKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPykckdCGKAFTQNSD 366
Cdd:COG5048 112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 367 LTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTgEKPFECVKCGKAFAISSNLSGHLRIHTGEKPFECLEC----- 441
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESprssl 265
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 442 GKAFTHSSSLNNH-MRTHSAK-KPFTCMECGKAFKFPTCVNLHMR--IHTGE--KPYKC--KQCGKSFSYSNSFQLHERT 513
Cdd:COG5048 266 PTASSQSSSPNESdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345
                       330       340       350
                ....*....|....*....|....*....|....*...
gi 37622349 514 HTGEKPYECK--ECGKAFSSSSSFRNHERRHADERLSA 549
Cdd:COG5048 346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKN 383
KRAB smart00349
krueppel associated box;
1-28 5.82e-08

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 49.51  E-value: 5.82e-08
                           10        20
                   ....*....|....*....|....*...
gi 37622349      1 MLENYKNLATVGYQLFKPSLISWLEQEE 28
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGE 57
zf-H2C2_2 pfam13465
Zinc-finger double domain;
482-503 1.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.17e-04
                          10        20
                  ....*....|....*....|..
gi 37622349   482 HMRIHTGEKPYKCKQCGKSFSY 503
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
295-342 9.27e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 9.27e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 37622349  295 PYECKECGIAFTRSSQLTEHLK--THTAKdpfeCKICGKSFRNSSCLSDH 342
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRytEHSKV----CPVCGKEFRNTDSTLDH 118
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
210-549 4.66e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 4.66e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 210 KPYKCKECGKGFRYSAYLNIHMGTHTGDNPYEC--KECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQ-H 286
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlS 111
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 287 MKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPykckdCGKAFTQNSD 366
Cdd:COG5048 112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 367 LTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTgEKPFECVKCGKAFAISSNLSGHLRIHTGEKPFECLEC----- 441
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESprssl 265
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 442 GKAFTHSSSLNNH-MRTHSAK-KPFTCMECGKAFKFPTCVNLHMR--IHTGE--KPYKC--KQCGKSFSYSNSFQLHERT 513
Cdd:COG5048 266 PTASSQSSSPNESdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345
                       330       340       350
                ....*....|....*....|....*....|....*...
gi 37622349 514 HTGEKPYECK--ECGKAFSSSSSFRNHERRHADERLSA 549
Cdd:COG5048 346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKN 383
KRAB smart00349
krueppel associated box;
1-28 5.82e-08

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 49.51  E-value: 5.82e-08
                           10        20
                   ....*....|....*....|....*...
gi 37622349      1 MLENYKNLATVGYQLFKPSLISWLEQEE 28
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGE 57
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
164-359 2.47e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 2.47e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 164 SFINHSHLQGHLRTHNGESlHEWKECGRGFIHSTDLAVRIQTH----------RSEKPYKCKECGKGFRYSAYLNIHMGT 233
Cdd:COG5048 233 SQLSPKSLLSQSPSSLSSS-DSSSSASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRS 311
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 234 --HTGDN--PYECKE--CGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCL-------SQHMKIHVGEKPYEC-- 298
Cdd:COG5048 312 vnHSGESlkPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLnneppqsLQQYKDLKNDKKSETls 391
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 37622349 299 KECGIAFTRSSQLTEHLKTHTAKDP--FECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGK 359
Cdd:COG5048 392 NSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
294-480 4.35e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.39  E-value: 4.35e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 294 KPYECKECGIAFTRSSQLTEHLKT--HTAKD--PFECKI--CGKSFRNSSCLSDHFRIHTGIKPYKCK--DCGKAFTQNS 365
Cdd:COG5048 288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGESlkPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLL 367
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 366 DLTKHARTH-----SGERPYEC--KECGKAFARSSRLSEHTRTHTGEKPfecvkcgkafaissnlsghlrihtgeKPFEC 438
Cdd:COG5048 368 NNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRP--------------------------YNCKN 421
                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 37622349 439 LECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVN 480
Cdd:COG5048 422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSN 463
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
335-538 1.97e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 1.97e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 335 NSSCLSDHFRIhtgIKPYKCKDCGKAFTQNSDLTKHART--HSGE--RPYECKE--CGKAFARSSRLSEHTRTHTGEKPF 408
Cdd:COG5048 276 NESDSSSEKGF---SLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPA 352
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 409 ECV--KCGKAFAISSNLSGHLRIH-----TGEKPFECLecgkaftHSSSLNNHMRTHSAKKPFTCmecgkafkfptcvNL 481
Cdd:COG5048 353 KEKllNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETL-------SNSCIRNFKRDSNLSLHIIT-------------HL 412
                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 37622349 482 HMRIHtgekPYKCKQCGKSFSYSNSFQLHERTHTGEKPYECkECGKAFSSSSSFRNH 538
Cdd:COG5048 413 SFRPY----NCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNH 464
zf-H2C2_2 pfam13465
Zinc-finger double domain;
482-503 1.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.17e-04
                          10        20
                  ....*....|....*....|..
gi 37622349   482 HMRIHTGEKPYKCKQCGKSFSY 503
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
506-531 4.30e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 4.30e-04
                          10        20
                  ....*....|....*....|....*.
gi 37622349   506 SFQLHERTHTGEKPYECKECGKAFSS 531
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
422-447 8.71e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 8.71e-04
                          10        20
                  ....*....|....*....|....*.
gi 37622349   422 NLSGHLRIHTGEKPFECLECGKAFTH 447
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
339-363 1.24e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.24e-03
                          10        20
                  ....*....|....*....|....*
gi 37622349   339 LSDHFRIHTGIKPYKCKDCGKAFTQ 363
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
352-374 1.45e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.12  E-value: 1.45e-03
                          10        20
                  ....*....|....*....|...
gi 37622349   352 YKCKDCGKAFTQNSDLTKHARTH 374
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
366-391 1.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.51e-03
                          10        20
                  ....*....|....*....|....*.
gi 37622349   366 DLTKHARTHSGERPYECKECGKAFAR 391
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
450-474 1.57e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.57e-03
                          10        20
                  ....*....|....*....|....*
gi 37622349   450 SLNNHMRTHSAKKPFTCMECGKAFK 474
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
255-278 2.26e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.26e-03
                          10        20
                  ....*....|....*....|....
gi 37622349   255 LTQHRKTHTGEKPYKCKDCGRAFT 278
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
432-515 2.76e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 2.76e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37622349 432 GEKPFEC--LECGKAFTHSSSLNNHMRtHSAKKPFTcmecgkafkFPTCVNLHMRIHTGE-KPYKCKQCGKSFSYSNSFQ 508
Cdd:COG5189 346 DGKPYKCpvEGCNKKYKNQNGLKYHML-HGHQNQKL---------HENPSPEKMNIFSAKdKPYRCEVCDKRYKNLNGLK 415

                ....*..
gi 37622349 509 LHeRTHT 515
Cdd:COG5189 416 YH-RKHS 421
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
436-458 2.96e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 2.96e-03
                          10        20
                  ....*....|....*....|...
gi 37622349   436 FECLECGKAFTHSSSLNNHMRTH 458
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
283-307 3.06e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.06e-03
                          10        20
                  ....*....|....*....|....*
gi 37622349   283 LSQHMKIHVGEKPYECKECGIAFTR 307
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
226-251 3.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.51e-03
                          10        20
                  ....*....|....*....|....*.
gi 37622349   226 YLNIHMGTHTGDNPYECKECGKAFTR 251
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
295-342 9.27e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 9.27e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 37622349  295 PYECKECGIAFTRSSQLTEHLK--THTAKdpfeCKICGKSFRNSSCLSDH 342
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRytEHSKV----CPVCGKEFRNTDSTLDH 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH