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Conserved domains on  [gi|2031835747|ref|NP_001381643|]
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protein GPR108 isoform 2 [Homo sapiens]

Protein Classification

lung seven transmembrane receptor family protein( domain architecture ID 10536224)

lung seven transmembrane receptor (LU7TM) family protein similar to mammalian orphan G-protein coupled receptor GPR107/108 and transmembrane protein 87A/B

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lung_7-TM_R pfam06814
Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic ...
 1-261 8.73e-90

Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.


:

Pssm-ID: 369089  Cd Length: 294  Bit Score: 269.19  E-value: 8.73e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747   1 MIREKNPDGFLSAAEMPLFKLYMVMSACFLAAGIFWVSILCRNTYSVFKIHWLMAALAFTKSISLLFHSINYYFINSQGH 80
Cdd:pfam06814  29 TVVWKNPYGYLSASEAPLMPFYGIMSLAYVLLGILWSFILFKYWHDILPIQKYIAAVIALGMAELAFHYIDYAFINSKGS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747  81 PIEGLAVMYYIAHLLKGALLFITIALIGSGWAFIKYVLSDKEKKVFGIVIPMQVLANVAYIIIESREEGASDYVLWKEIL 160
Cdd:pfam06814 109 SIEVLAVFASILSAAKKTLSRILLLIISLGYGIVKPTLGDTLSKVCGIGLLYFVAACVLFIVRESGEEGDSSYKLWLVLF 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747 161 FLVDLicCGAILFPVVWSIRHLQDaSGTDGKVAVNLAKLKLFRHYYVMVICYVYFTRIIAILLQVAV--------PFQWQ 232
Cdd:pfam06814 189 FLLPL--ALLDLFFVVWIFRSLQK-TLRDLRLRRNLVKLSLYRHFTNMLACSVVASFIIILVEKIYFvgtdmcnkYWKTL 265

                         250       260
                  ....*....|....*....|....*....
gi 2031835747 233 WLYQLLVEGSTLAFFVLTGYKFQPTGNNP 261
Cdd:pfam06814 266 WLITAFWDLLTLVLLVVICYLWRPSQNNP 294
 
Name Accession Description Interval E-value
Lung_7-TM_R pfam06814
Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic ...
 1-261 8.73e-90

Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.


Pssm-ID: 369089  Cd Length: 294  Bit Score: 269.19  E-value: 8.73e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747   1 MIREKNPDGFLSAAEMPLFKLYMVMSACFLAAGIFWVSILCRNTYSVFKIHWLMAALAFTKSISLLFHSINYYFINSQGH 80
Cdd:pfam06814  29 TVVWKNPYGYLSASEAPLMPFYGIMSLAYVLLGILWSFILFKYWHDILPIQKYIAAVIALGMAELAFHYIDYAFINSKGS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747  81 PIEGLAVMYYIAHLLKGALLFITIALIGSGWAFIKYVLSDKEKKVFGIVIPMQVLANVAYIIIESREEGASDYVLWKEIL 160
Cdd:pfam06814 109 SIEVLAVFASILSAAKKTLSRILLLIISLGYGIVKPTLGDTLSKVCGIGLLYFVAACVLFIVRESGEEGDSSYKLWLVLF 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747 161 FLVDLicCGAILFPVVWSIRHLQDaSGTDGKVAVNLAKLKLFRHYYVMVICYVYFTRIIAILLQVAV--------PFQWQ 232
Cdd:pfam06814 189 FLLPL--ALLDLFFVVWIFRSLQK-TLRDLRLRRNLVKLSLYRHFTNMLACSVVASFIIILVEKIYFvgtdmcnkYWKTL 265

                         250       260
                  ....*....|....*....|....*....
gi 2031835747 233 WLYQLLVEGSTLAFFVLTGYKFQPTGNNP 261
Cdd:pfam06814 266 WLITAFWDLLTLVLLVVICYLWRPSQNNP 294
 
Name Accession Description Interval E-value
Lung_7-TM_R pfam06814
Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic ...
 1-261 8.73e-90

Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.


Pssm-ID: 369089  Cd Length: 294  Bit Score: 269.19  E-value: 8.73e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747   1 MIREKNPDGFLSAAEMPLFKLYMVMSACFLAAGIFWVSILCRNTYSVFKIHWLMAALAFTKSISLLFHSINYYFINSQGH 80
Cdd:pfam06814  29 TVVWKNPYGYLSASEAPLMPFYGIMSLAYVLLGILWSFILFKYWHDILPIQKYIAAVIALGMAELAFHYIDYAFINSKGS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747  81 PIEGLAVMYYIAHLLKGALLFITIALIGSGWAFIKYVLSDKEKKVFGIVIPMQVLANVAYIIIESREEGASDYVLWKEIL 160
Cdd:pfam06814 109 SIEVLAVFASILSAAKKTLSRILLLIISLGYGIVKPTLGDTLSKVCGIGLLYFVAACVLFIVRESGEEGDSSYKLWLVLF 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2031835747 161 FLVDLicCGAILFPVVWSIRHLQDaSGTDGKVAVNLAKLKLFRHYYVMVICYVYFTRIIAILLQVAV--------PFQWQ 232
Cdd:pfam06814 189 FLLPL--ALLDLFFVVWIFRSLQK-TLRDLRLRRNLVKLSLYRHFTNMLACSVVASFIIILVEKIYFvgtdmcnkYWKTL 265

                         250       260
                  ....*....|....*....|....*....
gi 2031835747 233 WLYQLLVEGSTLAFFVLTGYKFQPTGNNP 261
Cdd:pfam06814 266 WLITAFWDLLTLVLLVVICYLWRPSQNNP 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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